2025 ICD-10-CM Diagnosis Code G60.1
Refsum's disease
- ICD-10-CM Code:
- G60.1
- ICD-10 Code for:
- Refsum's disease
- Is Billable?
- Yes - Valid for Submission
- Chronic Condition Indicator: [1]
- Chronic
- Code Navigator:
G60.1 is a billable diagnosis code used to specify a medical diagnosis of refsum's disease. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2024 through September 30, 2025.
Approximate Synonyms
The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.
- Ataxia co-occurrent and due to phytanic acid storage disease
- Autonomic neuropathy due to Refsum Disease
- Cardiomyopathy due to storage disease
- Dilated cardiomyopathy due to metabolic disorder
- Dilated cardiomyopathy due to phytanic acid storage disease
- HSMN IV
- HSMN IV
- Infantile Refsum's disease
- Loss of multiple peroxisomal functions
- Ophthalmoplegia due to neuropathy
- Ophthalmoplegia due to phytanic acid storage disease
- Pseudoinfantile Refsum's disease
Clinical Classification
Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.
They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.
Polyneuropathies
CCSR Code: NVS015
Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.
Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.
Tabular List of Diseases and Injuries
The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.
Inclusion Terms
Inclusion TermsThese terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- Infantile Refsum disease
Index to Diseases and Injuries References
The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).
- - Disease, diseased - See Also: Syndrome;
- - Heredopathia atactica polyneuritiformis - G60.1
- - Neuropathy, neuropathic - G62.9
- - hypertrophic - G60.0
- - Refsum - G60.1
- - hypertrophic - G60.0
- - Polyneuritis, polyneuritic - See Also: Polyneuropathy;
- - hereditary ataxic - G60.1
- - Refsum's disease or syndrome - G60.1
Convert G60.1 to ICD-9-CM
Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.
Refsum's disease
ICD-9-CM: 356.3
This is a direct match with no additional mapping qualifiers. The absence of a flag generally means the mapping is considered exact or precise. In other words, the ICD-10 code maps cleanly to the ICD-9 code without qualification, approximation, or needing multiple codes.
Patient Education
Peripheral Nerve Disorders
What are peripheral nerves?
Nerves are like wires that carry messages back and forth between your brain and your body. Your peripheral nerves branch off from your brain and spinal cord and connect to all parts of your body, including your muscles and organs. Peripheral nerves carry messages from your brain that control your movement, breathing, heartbeat, digestion, and more. They also carry messages from your body to your brain, so you can feel things, such as pain, heat, and cold.
What are peripheral nerve disorders?
Peripheral nerve disorders happen when one or more peripheral nerves are damaged. Damaged nerves may not carry messages correctly, or they may not work at all. As a result, you may have pain, trouble walking, or a variety of other problems, depending on which nerves are involved.
Peripheral nerve disorders are very common. There are more than 100 different types.
What causes peripheral nerve disorders?
Many things can damage nerves and lead to peripheral nerve disorders:
- Diabetes is the most common cause of peripheral nerve disorders. Most people with diabetes will develop diabetic nerve problems.
- Physical injury (trauma) that stretches, crushes, squeezes, cuts, or puts pressure on one or more nerves. Some examples of peripheral nerve disorders from physical injury include complex regional pain syndrome and brachial plexus injuries.
- Health conditions, including:
- Certain cancers and their treatment (chemotherapy and radiation therapy).
- Infections, such as HIV and Lyme disease.
- Problems with blood or blood vessels.
- Autoimmune diseases, such as rheumatoid arthritis and lupus.
- Kidney or liver disease.
- Certain medicines.
- Contact with certain toxic substances, such as lead or mercury.
- Alcohol use disorder (AUD) and smoking.
- Vitamin imbalances, especially a lack of vitamin B12.
- Your genes, including changes in your genes or conditions that you inherit from your parents, such as Charcot-Marie-Tooth disease.
In certain cases, the cause of peripheral nerve disorder is not known.
What are the symptoms of peripheral nerve disorders?
The symptoms of peripheral nerve disorders depend on which nerves are affected, what is causing the damage, and how serious it is:
Types of nerves | Possible symptoms of nerve damage |
---|---|
Motor nerves control your muscles and all your movement, such as walking, talking, and using your hands. |
|
Sensory nerves carry messages to your brain from your senses, including touch, hot and cold, and pain. |
|
Autonomic nerves send messages to your organs to control breathing, digestion, and other body functions that happen without thinking about them. |
|
Symptoms may range from mild to very strong. They may develop quickly over days or slowly over months and years. But they are rarely life-threatening.
How are peripheral nerve disorders diagnosed?
To find out if you have a peripheral nerve disorder, your provider will:
- Ask about your medical history
- Ask about your family health history
- Do a physical exam
- Order tests, which may include:
- Blood tests
- Genetic tests
- Nerve tests that measure:
- Electrical activity in your nerves and muscles
- How well your autonomic nerves are working
- A biopsy of nerve or skin tissue
- CT or MRI scan to see what may be pressing on your nerves
What are the treatments for peripheral nerve disorders?
It's important to treat any conditions that are causing nerve damage. In certain cases, that will allow your nerves to heal over time.
Treatment for symptoms depends on the type of peripheral nerve disorder you have, where it is, and how severe. Treatment options include:
- Braces or splints
- Over-the-counter patches and skin creams
- Prescription medicines
- Non-drug pain management, such as electrical stimulation or relaxation therapy
- Surgery to relieve pressure on a nerve
Can peripheral nerve disorders be prevented?
You can help prevent peripheral nerve disorders by:
- Managing health conditions that may cause nerve damage, especially diabetes
- Preventing falls and accidents
- Avoiding toxic substances
- Being careful to avoid repeated motions and body positions that press on your nerves
- Eating a balanced diet, exercising, limiting alcohol, and not smoking
NIH: National Institute of Neurological Disorders and Stroke
[Learn More in MedlinePlus]
Refsum disease
Refsum disease is an inherited condition that causes vision loss, absence of the sense of smell (anosmia), and a variety of other signs and symptoms.
The vision loss associated with Refsum disease is caused by an eye disorder called retinitis pigmentosa. This disorder affects the retina, the light-sensitive layer at the back of the eye. Vision loss occurs as the light-sensing cells of the retina gradually deteriorate. The first sign of retinitis pigmentosa is usually a loss of night vision, which often becomes apparent in childhood. Over a period of years, the disease disrupts side (peripheral) vision and may eventually lead to blindness.
Vision loss and anosmia are seen in almost everyone with Refsum disease, but other signs and symptoms vary. About one-third of affected individuals are born with bone abnormalities of the hands and feet. Features that appear later in life can include progressive muscle weakness and wasting; poor balance and coordination (ataxia); hearing loss; and dry, scaly skin (ichthyosis). Additionally, some people with Refsum disease develop an abnormal heart rhythm (arrhythmia) and related heart problems that can be life-threatening.
[Learn More in MedlinePlus]
Zellweger spectrum disorder
Zellweger spectrum disorder is a condition that affects many parts of the body. Cases of Zellweger spectrum disorder are often categorizes as severe, intermediate, or mild.
Individuals with severe Zellweger spectrum disorder usually have signs and symptoms at birth, which worsen over time. These infants experience weak muscle tone (hypotonia), feeding problems, hearing and vision loss, and seizures. These problems are caused by reduced myelin, which is the covering that protects nerves and promotes the efficient transmission of nerve impulses. The part of the brain and spinal cord that contains myelin is called white matter. Reduced myelin (demyelination) leads to loss of white matter (leukodystrophy).
Children with severe Zellweger spectrum disorder also develop life-threatening problems in other organs and tissues, such as the liver, heart, and kidneys, and their liver or spleen may be enlarged. They may have skeletal abnormalities, including a large space between the bones of the skull (fontanelles) and characteristic bone spots known as chondrodysplasia punctata that can be seen on x-ray. Affected individuals can have eye abnormalities, including clouding of the lenses of the eyes (cataracts) or involuntary, side-to-side movements of the eyes (nystagmus). Severe Zellweger spectrum disorder involves distinctive facial features, including a flattened face, broad nasal bridge, high forehead, and widely spaced eyes (hypertelorism). Children with severe Zellweger spectrum disorder typically do not survive beyond the first year of life.
People with intermediate or mild Zellweger spectrum disorder have more variable features that progress more slowly than those with the severe form. Affected children usually do not develop signs and symptoms of the disease until late infancy or early childhood. Children with these intermediate and mild forms often have hypotonia, vision problems, hearing loss, liver dysfunction, developmental delay, and some degree of intellectual disability. Most people with the intermediate form survive into childhood, and those with the mild form may reach adulthood. In rare cases, individuals at the mildest end of the condition spectrum have developmental delay in childhood and hearing loss or vision problems beginning in adulthood and do not develop the other features of this disorder.
The severe, intermediate, and mild forms of Zellweger spectrum disorder were once thought to be distinct disorders. The severe form was known as Zellweger syndrome, the intermediate form was neonatal adrenoleukodystrophy (NALD), and the mild form was infantile Refsum disease. These conditions were renamed as a single condition when they were found to be part of the same condition spectrum.
[Learn More in MedlinePlus]
Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.