1. Home
  2. ICD-10-CM Codes
  3. Z00–Z99
  4. Z40-Z53
  5. Z40
  6. 2026 ICD-10-CM Code Z40.81

2026 ICD-10-CM Diagnosis Code Z40.81

Encounter for prophylactic surgery for removal of ovary(s) for persons without known genetic/familial risk factors

ICD-10-CM Code:
Z40.81
ICD-10 Code for:
Enc for proph surg for remov ovary(s) w/o gen/fam risk fctrs
Is Billable?
Yes - Valid for Submission
Code Navigator:

Z40.81 is a billable diagnosis code used to specify a medical diagnosis of encounter for prophylactic surgery for removal of ovary(s) for persons without known genetic/familial risk factors. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.

Code Classification

  • Factors influencing health status and contact with health services
    Z00–Z99
    • Encounters for other specific health care
      Z40-Z53
      • Encounter for prophylactic surgery
        Z40

New 2026 ICD-10-CM Code

Z40.81 is new to ICD-10-CM code set for the FY 2026, effective October 1, 2025. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2025. This is a new and revised code for the FY 2026 (October 1, 2025 - September 30, 2026).

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Encounter for prophylactic oophorectomy for persons without known genetic/ familial risk factors

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Index of External Cause of Injuries

References found for this diagnosis code in the External Cause of Injuries Index:

    • Admission(for)
      • prophylactic (measure)
        • oophorectomy for persons without known genetic/ familial risk factors
    • Admission(for)
      • prophylactic (measure)
        • organ removal
          • ovary (s)
            • for persons without known genetic/familial risk factors

Present on Admission (POA)

Z40.81 is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.

CMS POA Indicator Options and Definitions

POA Indicator: Y

Reason: Diagnosis was present at time of inpatient admission.

CMS Pays CC/MCC DRG? YES

POA Indicator: N

Reason: Diagnosis was not present at time of inpatient admission.

CMS Pays CC/MCC DRG? NO

POA Indicator: U

Reason: Documentation insufficient to determine if the condition was present at the time of inpatient admission.

CMS Pays CC/MCC DRG? NO

POA Indicator: W

Reason: Clinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.

CMS Pays CC/MCC DRG? YES

POA Indicator: 1

Reason: Unreported/Not used - Exempt from POA reporting.

CMS Pays CC/MCC DRG? NO

Replacement Code

Z4081 replaces the following previously assigned ICD-10-CM code(s):

  • Z40.8 - Encounter for other prophylactic surgery

Code History

  • FY 2026 - Code Added, effective from 10/1/2025 through 9/30/2026