2026 ICD-10-CM Diagnosis Code C41.1Malignant neoplasm of mandible

ICD-10-CM CodesC00–D49C40-C41C41

ICD-10-CM C41.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C41.1 is a billable ICD-10-CM diagnosis code for malignant neoplasm of mandible. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 542 through 544. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Bone cancer.

Code Identity

ICD-10-CM Code
C41.1
Billable Status
Yes — Valid for Submission
Code Describes
Malignant neoplasm of mandible
Short Description
Malignant neoplasm of mandible
Same as the full description in the CMS dataset.
Parent Code
Malignant neoplasm of bone and articular cartilage of other and unspecified sites

Code Classification

ChapterC00–D49Neoplasms
SectionC40-C41Malignant neoplasms of bone and articular cartilage
CategoryC41Malignant neoplasm of bone and articular cartilage of other and unspecified sites
This CodeC41.1Malignant neoplasm of mandible

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Carcinoma of mandible
  • Chondrosarcoma of mandible
  • Malignant ameloblastoma of mandible
  • Malignant dedifferentiated adamantinoma of bone
  • Malignant neoplasm of alveolus of mandible
  • Malignant neoplasm of mandible
  • Malignant odontogenic neoplasm of lower jaw
  • Odontogenic ghost cell carcinoma
  • Osteosarcoma of bone of head
  • Periosteal osteosarcoma
  • Periosteal osteosarcoma of jaw
  • Primary ameloblastic carcinoma
  • Primary chondrosarcoma of mandible
  • Primary malignant ameloblastoma of mandible
  • Primary malignant neoplasm of jaw
  • Primary malignant neoplasm of mandible
  • Primary malignant odontogenic neoplasm of lower jaw
  • Primary odontogenic ghost cell carcinoma
  • Primary osteosarcoma of articular cartilage of jaw
  • Primary osteosarcoma of bone of head
  • Primary osteosarcoma of bone of jaw
  • Primary osteosarcoma of mandible
  • Primary periosteal osteosarcoma of jaw
  • Sarcoma of mandible

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Malignant neoplasm of inferior maxilla
  • Malignant neoplasm of lower jaw bone

Type 2 Excludes

  • carcinoma, any type except intraosseous or odontogenic of:
  • jaw NOS C03.9
  • lower C03.1
  • malignant neoplasm of upper jaw bone C41.0

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Adamantinoma
      • malignant
    • Adamantinoma
      • malignant
        • jaw (bone) (lower)
    • Ameloblastoma
      • malignant
    • Ameloblastoma
      • malignant
        • jaw (bone) (lower)
    • Carcinoma(malignant)
      • ameloblastic
    • Carcinoma(malignant)
      • intraosseous
    • Carcinoma(malignant)
      • odontogenic
    • Fibrosarcoma
      • ameloblastic
    • Fibrosarcoma
      • odontogenic
    • Odontosarcoma, ameloblastic
    • Sarcoma(of)
      • ameloblastic
    • Sarcoma(of)
      • odontogenic
    • Tumor
      • odontogenic (adenomatoid) (benign) (calcifying epithelial) (keratocystic) (squamous)
        • malignant

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO023
Bone cancer
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Cementoma

    an odontogenic fibroma in which cells have developed into cementoblasts and which consists largely of cementum.
  • Mandible

    the largest and strongest bone of the face constituting the lower jaw. it supports the lower teeth.

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
alveolar ridge or processC41.1C79.51D16.5D48.0D49.2
alveolar ridge or process lowerC41.1C79.51D16.5D48.0D49.2
bone (periosteum) jaw (lower)C41.1C79.51D16.5D48.0D49.2
bone (periosteum) mandibleC41.1C79.51D16.5D48.0D49.2
bone (periosteum) maxilla, maxillary (superior) inferiorC41.1C79.51D16.5D48.0D49.2
jaw boneC41.1C79.51D16.5D48.0D49.2
jaw bone lowerC41.1C79.51D16.5
joint NEC [See Also: Neoplasm, bone] temporomandibularC41.1C79.51D16.5D48.0D49.2
mandibleC41.1C79.51D16.5D48.0D49.2
mandible alveolar ridge or processC41.1C79.51D16.5D48.0D49.2

Patient EducationClinical

Bone Cancer

Cancer that starts in a bone is uncommon. Cancer that has spread to the bone from another part of the body is more common.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C41.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
170.1 Malignant neo mandible
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C41.1Overview

Is C41.1 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of mandible on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C41.1 group to?

When malignant neoplasm of mandible is the principal diagnosis on an inpatient stay, it groups to MS-DRG 542, 543, 544, with relative weights from 0.7546 to 1.7665 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C41.1?

Under the General Equivalence Mappings, malignant neoplasm of mandible converts to ICD-9-CM 170.1 (malignant neo mandible). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.