2026 ICD-10-CM Diagnosis Code C41.1Malignant neoplasm of mandible
ICD-10-CM Codes›C00–D49›C40-C41›C41
- Billable — Valid for Submission
- CC — Complication or Comorbidity
- Risk Adjusts — HCC 21
- Chronic Condition
C41.1 is a billable ICD-10-CM diagnosis code for malignant neoplasm of mandible. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 11 through 13, 542 through 544. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 9 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Bone cancer.
For Medicare Advantage risk adjustment, C41.1 maps to CMS-HCC Category 21 (Lymphoma and Other Cancers) under the V28 model, adding a risk factor of about 0.671 for a community, non-dual, aged beneficiary in payment year 2026.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
C41.1 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2026.
Source: CMS Payment Year 2026 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Carcinoma of mandible
- Chondrosarcoma of mandible
- Malignant ameloblastoma of mandible
- Malignant dedifferentiated adamantinoma of bone
- Malignant neoplasm of alveolus of mandible
- Malignant neoplasm of mandible
- Malignant odontogenic neoplasm of lower jaw
- Odontogenic ghost cell carcinoma
- Osteosarcoma of bone of head
- Periosteal osteosarcoma
- Periosteal osteosarcoma of jaw
- Primary ameloblastic carcinoma
- Primary chondrosarcoma of mandible
- Primary malignant ameloblastoma of mandible
- Primary malignant neoplasm of jaw
- Primary malignant neoplasm of mandible
- Primary malignant odontogenic neoplasm of lower jaw
- Primary odontogenic ghost cell carcinoma
- Primary osteosarcoma of articular cartilage of jaw
- Primary osteosarcoma of bone of head
- Primary osteosarcoma of bone of jaw
- Primary osteosarcoma of mandible
- Primary periosteal osteosarcoma of jaw
- Sarcoma of mandible
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Malignant neoplasm of inferior maxilla
- Malignant neoplasm of lower jaw bone
Type 2 Excludes
- carcinoma, any type except intraosseous or odontogenic of:
- jaw NOS C03.9
- lower C03.1
- malignant neoplasm of upper jaw bone C41.0
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Adamantinoma See Also: Cyst, calcifying odontogenic;
malignant C41.1
jaw (bone) (lower) C41.1
Ameloblastoma See Also: Cyst, calcifying odontogenic;
malignant C41.1
jaw (bone) (lower) C41.1
Carcinoma (malignant) See Also: Neoplasm, by site, malignant;
ameloblastic C41.1
intraosseous C41.1
odontogenic C41.1
Fibrosarcoma See Also: Neoplasm, connective tissue, malignant;
ameloblastic C41.1
odontogenic C41.1
Sarcoma (of) See Also: Neoplasm, connective tissue, malignant;
ameloblastic C41.1
odontogenic C41.1
Tumor See Also: Neoplasm, unspecified behavior, by site;
odontogenic (adenomatoid) (benign) (calcifying epithelial) (keratocystic) (squamous) See: Cyst, calcifying odontogenic;
malignant C41.1
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Cementoma
an odontogenic fibroma in which cells have developed into cementoblasts and which consists largely of cementum.Mandible
the largest and strongest bone of the face constituting the lower jaw. it supports the lower teeth.
Table of NeoplasmsClinical
Anatomical sites in the Table of Neoplasms that reference this code family.
| Site | Malig. Primary | Malig. Secondary | Ca in situ | Benign | Uncertain | Unspec. |
|---|---|---|---|---|---|---|
| alveolar › ridge or process | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| alveolar › ridge or process › lower | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| bone (periosteum) › jaw (lower) | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| bone (periosteum) › mandible | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| bone (periosteum) › maxilla, maxillary (superior) › inferior | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| jaw › bone | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| jaw › bone › lower | C41.1 | C79.51 | – | D16.5 | – | – |
| joint NEC [See Also: Neoplasm, bone] › temporomandibular | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| mandible | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| mandible › alveolar › ridge or process | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
Patient EducationClinical
Bone Cancer
Cancer that starts in a bone is uncommon. Cancer that has spread to the bone from another part of the body is more common.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert C41.1 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About C41.1Overview
What is the ICD-10 code for malignant neoplasm of mandible?
The ICD-10-CM code for malignant neoplasm of mandible is C41.1 (sometimes written as C411). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Is C41.1 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of mandible on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does C41.1 group to?
When malignant neoplasm of mandible is the principal diagnosis on an inpatient stay, it groups to MS-DRG 11, 12, 13, 542, 543, 544, with relative weights from 0.7546 to 5.4541 depending on complications. Higher weights mean higher Medicare reimbursement.
Is C41.1 a CC or MCC?
CMS lists C41.1 as a CC (complication or comorbidity) for FY 2026. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 9 closely related codes in its exclusion list.
What is the ICD-9 equivalent of C41.1?
Under the General Equivalence Mappings, malignant neoplasm of mandible converts to ICD-9-CM 170.1 (malignant neo mandible). The mapping is a direct match.
What HCC is C41.1?
C41.1 (malignant neoplasm of mandible) maps to CMS-HCC Category 21 (Lymphoma and Other Cancers), commonly written as HCC 21, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2026. It mapped to HCC 10 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 22.
Does C41.1 risk-adjust for Medicare Advantage payment?
Yes. When documented and reported on a Medicare Advantage encounter, C41.1 adds a risk adjustment factor of about 0.671 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.493 to 0.739 depending on the payment segment). A more severe related category (HCC 17, HCC 18, HCC 19, and HCC 20) supersedes it when both are reported. See the full factor table on the HCC 21 category page.
