A22.7 - Anthrax sepsis

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• Sepsis due to Bacillus anthracis

Clinical Information

• Anthrax-. an acute infection caused by the spore-forming bacteria bacillus anthracis. it commonly affects hoofed animals such as sheep and goats. infection in humans often involves the skin (cutaneous anthrax), the lungs (inhalation anthrax), or the gastrointestinal tract. anthrax is not contagious and can be treated with antibiotics.
• Anthrax Vaccines-. vaccines or candidate vaccines used to prevent anthrax.
• Bacillus anthracis-. a species of bacteria that causes anthrax in humans and animals.
• Anthrax-. an infection caused by bacillus anthracis bacteria. it may affect the lungs, gastrointestinal tract, or skin. patients with lung infection present with fever, headaches, cough, chest pain and shortness of breath. patients with gastrointestinal infection present with nausea, vomiting and bloody diarrhea. patients with skin infection develop blisters and ulcers.
• Anthrax Toxin Receptor 1|ANTXR1|Tumor Endothelial Marker 8-. anthrax toxin receptor 1 (564 aa, ~63 kda) is encoded by the human antxr1 gene. this protein plays a role in the regulation of both cell adhesion and cellular motility.
• ANTXR1 Gene|ANTXR1|ANTXR1|Anthrax Toxin Receptor 1 Gene-. this gene plays a role in cell-matrix adhesion.
• ANTXR1 wt Allele|ATR|Anthrax Toxin Receptor 1 wt Allele|FLJ10601|FLJ21776|TEM8-. human antxr1 wild-type allele is located in the vicinity of 2p13.1 and is approximately 236 kb in length. this allele, which encodes anthrax toxin receptor 1 protein, is involved in the modulation of cytoskeletal rearrangement, cellular adhesion and cell migration. mutation of the gene is associated with hemangioma capillary infantile.

Diagnostic Related Groups - MS-DRG Mapping

The is diagnosis code is grouped in the following groups for version MS-DRG V40.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC). applicable from 10/01/2022 through 09/30/2023.

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Patient Education

Anthrax

Anthrax is a disease caused by Bacillus anthracis, a germ that lives in soil. Many people know about it from the 2001 bioterror attacks. In the attacks, someone purposely spread anthrax through the U.S. mail. This killed five people and made 22 sick.

Anthrax is rare. It affects animals such as cattle, sheep, and goats more often than people. People can get anthrax from contact with infected animals, wool, meat, or hides. It can cause three forms of disease in people. They are:

• Cutaneous, which affects the skin. People with cuts or open sores can get it if they touch the bacteria.
• Inhalation, which affects the lungs. You can get this if you breathe in spores of the bacteria.
• Gastrointestinal, which affects the digestive system. You can get it by eating infected meat.

Antibiotics often cure anthrax if it is diagnosed early. But many people don't know they have anthrax until it is too late to treat. A vaccine to prevent anthrax is available for people in the military and others at high risk.

Sepsis

What is sepsis?

Sepsis is your body's overactive and extreme response to an infection. Sepsis is a life-threatening medical emergency. Without quick treatment, it can lead to tissue damage, organ failure, and even death.

What causes sepsis?

Sepsis happens when an infection you already have triggers a chain reaction throughout your body. Bacterial infections are the most common cause, but other types of infections can also cause it.

The infections are often in the lungs, stomach, kidneys, or bladder. It's possible for sepsis to begin with a small cut that gets infected or with an infection that develops after surgery. Sometimes, sepsis can occur in people who didn't even know that they had an infection.

Who is at risk for sepsis?

Anyone with an infection could get sepsis. But certain people are at higher risk:

• Adults 65 or older
• People with chronic conditions, such as diabetes, lung disease, cancer, and kidney disease
• People with weakened immune systems
• Pregnant women
• Children younger than one

What are the symptoms of sepsis?

Sepsis can cause one or more of these symptoms:

• Rapid breathing and heart rate
• Shortness of breath
• Confusion or disorientation
• Extreme pain or discomfort
• Fever, shivering, or feeling very cold
• Clammy or sweaty skin

It's important to get medical care right away if you think you might have sepsis or if your infection is not getting better or is getting worse.

What other problems can sepsis cause?

Severe cases of sepsis can lead to septic shock, where your blood pressure drops to a dangerous level and multiple organs can fail.

How is sepsis diagnosed?

Your health care provider may use many tools to make a diagnosis:

• A medical history, which includes asking about your symptoms
• A physical exam, including checking vital signs (your temperature, blood pressure, heart rate, and breathing)
• Lab tests that check for signs of infection or organ damage
• Imaging tests such as an x-ray or a CT scan to find the location of the infection

Many of the signs and symptoms of sepsis can also be caused by other medical conditions. This may make sepsis hard to diagnose in its early stages.

What are the treatments for sepsis?

It is very important to get treatment right away. Treatment usually includes:

• Antibiotics
• Maintaining blood flow to organs. This may involve getting oxygen and intravenous (IV) fluids.
• Treating the source of the infection
• If needed, medicines to increase blood pressure

In serious cases, you might need kidney dialysis or a breathing tube. Some people need surgery to remove tissue damaged by the infection.

Can sepsis be prevented?

To prevent sepsis, you should try to prevent getting an infection:

• Take good care of any chronic health conditions that you have
• Get recommended vaccines
• Practice good hygiene, such as handwashing
• Keep cuts clean and covered until healed

NIH: National Institute of General Medical SciencesCenters for Disease Control and Prevention

Code History

• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)