2026 ICD-10-CM Diagnosis Code E75Disorders of sphingolipid metabolism and other lipid storage disorders

ICD-10-CM Codes›E00–E89›E70-E88›E75

ICD-10-CM E75
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E75 is a non-billable ICD-10-CM category code for disorders of sphingolipid metabolism and other lipid storage disorders, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E75.00, E75.01, E75.02, and E75.09.

Code Identity

ICD-10-CM Code
E75
Billable Status
No — Non-Billable Category
Code Describes
Disorders of sphingolipid metabolism and other lipid storage disorders
Chapter
E70-E88
Metabolic disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE75Disorders of sphingolipid metabolism and other lipid storage disorders
This CodeE75Disorders of sphingolipid metabolism and other lipid storage disorders

Specific Coding for Disord of sphingolipid metab and oth lipid storage disordersOverview

Non-specific codes like E75 require more characters. Use one of these billable codes instead:

  • E75.0 for GM2 gangliosidosis

  • Use E75.00 for GM2 gangliosidosis, unspecified

  • Use E75.01 for Sandhoff disease

  • Use E75.02 for Tay-Sachs disease

  • Use E75.09 for Other GM2 gangliosidosis

  • E75.1 for Other and unspecified gangliosidosis

  • Use E75.10 for Unspecified gangliosidosis

  • Use E75.11 for Mucolipidosis IV

  • Use E75.19 for Other gangliosidosis

  • E75.2 for Other sphingolipidosis

  • Use E75.21 for Fabry (-Anderson) disease

  • Use E75.22 for Gaucher disease

  • Use E75.23 for Krabbe disease

  • E75.24 for Niemann-Pick disease

  • Use E75.25 for Metachromatic leukodystrophy

  • Use E75.26 for Sulfatase deficiency

  • Use E75.27 for Pelizaeus-Merzbacher disease

  • Use E75.28 for Canavan disease

  • Use E75.29 for Other sphingolipidosis

  • Use E75.3 for Sphingolipidosis, unspecified

  • Use E75.4 for Neuronal ceroid lipofuscinosis

  • Use E75.5 for Other lipid storage disorders

  • Use E75.6 for Lipid storage disorder, unspecified

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

Patient EducationClinical

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Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E75Overview

Is E75 a billable code?

No. This is a category header that groups the codes for disorders of sphingolipid metabolism and other lipid storage disorders, and headers cannot be submitted on claims. Claims for disorders of sphingolipid metabolism and other lipid storage disorders need a more specific code from this category, such as E75.00, E75.01, and E75.02.