ICD-10 Diagnosis Code M46.21

Osteomyelitis of vertebra, occipito-atlanto-axial region

Diagnosis Code M46.21

ICD-10: M46.21
Short Description: Osteomyelitis of vertebra, occipito-atlanto-axial region
Long Description: Osteomyelitis of vertebra, occipito-atlanto-axial region
This is the 2017 version of the ICD-10-CM diagnosis code M46.21

Valid for Submission
The code M46.21 is valid for submission for HIPAA-covered transactions.

Code Classification
  • Diseases of the musculoskeletal system and connective tissue (M00–M99)
    • Spondylopathies (M45-M49)
      • Other inflammatory spondylopathies (M46)

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code M46.21 is grouped in the following Diagnostic Related Group(s) (MS-DRG v33.0)

  • SPINAL FUSION EXCEPT CERVICAL WITH SPINAL CURVATURE OR MALIGNANCY OR INFECTION OR EXTENSIVE FUSIONS WITH MCC 456
  • SPINAL FUSION EXCEPT CERVICAL WITH SPINAL CURVATURE OR MALIGNANCY OR INFECTION OR EXTENSIVE FUSIONS WITH CC 457
  • SPINAL FUSION EXCEPT CERVICAL WITH SPINAL CURVATURE OR MALIGNANCY OR INFECTION OR EXTENSIVE FUSIONS WITHOUT CC/MCC 458

Convert to ICD-9 Additional informationCallout TooltipGeneral Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

Information for Patients


Bone Infections

Like other parts of the body, bones can get infected. The infections are usually bacterial, but can also be fungal. They may spread to the bone from nearby skin or muscles, or from another part of the body through the bloodstream. People who are at risk for bone infections include those with diabetes, poor circulation, or recent injury to the bone. You may also be at risk if you are having hemodialysis.

Symptoms of bone infections include

  • Pain in the infected area
  • Chills and fever
  • Swelling, warmth, and redness

A blood test or imaging test such as an x-ray can tell if you have a bone infection. Treatment includes antibiotics and often surgery.

  • Bone lesion biopsy
  • Bone pain or tenderness
  • Disseminated tuberculosis
  • Osteomyelitis
  • Osteomyelitis - discharge


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