2025 ICD-10-CM Diagnosis Code L81.4

Approximate Synonyms

The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.

Clinical Classification

Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.

They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.

Clinical Information

• Melanosis

  disorders of increased melanin pigmentation that develop without preceding inflammatory disease.

• Becker Nevus|Becker's Nevus|Linear Papular Ectodermal-Mesodermal Hamartoma|Melanosis Neviformis|Pigmented Hairy Epidermal Nevus|Pigmented Hairy Nevus of Becker|Progressive Cribriform and Zosteriform Hyperpigmentation

  a benign lesion that is sometimes congenital and consists of an overgrowth of the epidermis and the presence of melanin-containing cells. it is found mostly in males and typically develops during childhood or adolescence, becoming darker and more hairy after puberty.

• Conjunctival Melanocytic Intraepithelial Lesion|C-MIL|C-MIN|Conjunctival Melanocytic Intraepithelial Neoplasia|Conjunctival Primary Acquired Melanosis with Atypia|PAM with Atypia|Primary Acquired Melanosis with Atypia

  a spectrum of neoplastic changes that occur in the conjunctiva and range from melanocytic hyperplasia through degrees of atypia to melanoma in situ. the lesions are generally unilateral but often multifocal and appear as flat, irregular brown discolorations of the conjunctiva. they usually affect middle-aged and elderly caucasians. (who 2018)

• High Grade Conjunctival Melanocytic Intraepithelial Lesion|High Grade C-MIL|High-Grade C-MIL|High-Grade Conjunctival Melanocytic Intraepithelial Lesion|PAM with Moderate to Severe Atypia|Primary Acquired Melanosis with Moderate to Severe Atypia

  conjunctival melanocytic intraepithelial lesion characterized by the presence of moderate to severe atypia.

• Intraepithelial Melanocytic Hyperplasia|Benign Acquired Melanosis

  a hyperplasia of the intraepithelial melanocytes.

• Low Grade Conjunctival Melanocytic Intraepithelial Lesion|Low Grade C-MIL|Low-Grade C-MIL|Low-Grade Conjunctival Melanocytic Intraepithelial Lesion|PAM with Mild Atypia|Primary Acquired Melanosis with Mild Atypia

  conjunctival melanocytic intraepithelial lesion characterized by the presence of mild atypia.

• Melanoma in Precancerous Melanosis|Malignant Cutaneous (Skin) Melanoma in Precancerous Melanosis|Malignant Melanoma in Precancerous Melanosis|Malignant melanoma in precancerous melanosis

  a melanoma arising from an atypical intraepithelial melanocytic hyperplasia.

• Melanosis

  a benign congenital or acquired lesion that arises from mucosal sites and is characterized by melanin pigment deposition in the basilar keratinocytes. it may be associated with a slight proliferation of junctional melanocytes. it presents as a single or multiple pigmented macules or patches in the external genitalia, anorectal region, distal urinary tract, and oral cavity.

• Meningeal Melanocytosis|Diffuse Melanocytosis|Diffuse Melanosis|Diffuse Meningeal Melanocytosis|Diffuse melanocytosis

  a diffuse or multifocal proliferation of uniform nevoid polygonal cells in the leptomeninges. cells may spread into the virchow-robin spaces without frank invasion of the brain. diffuse melanocytosis carries a poor prognosis even in the absence of histologic malignancy. (who)

• Neurocutaneous Melanosis|NCM|Neurocutaneous Melanocytosis

  a congenital condition characterized by the presence of giant and/or multiple satellite congenital melanocytic nevi in the skin and benign melanocytic pigmentation of the leptomeninges.

• Nevus of Ito|Hypomelanosis of Ito|Ito's Nevus

  a large brown, blue, or gray hamartoma of dermal melanocytes, usually on the shoulder and upper arm that is most commonly found in asian populations and in females. it is sometimes associated with sensory changes in the involved skin area, but very rarely becomes cancerous.

• Ocular Melanocytosis|Melanosis Oculi

  a congenital abnormality characterized by the presence of an increased population of non-proliferating hyperpigmented melanocytes in the sclera, iris, ciliary body, choroid, and orbit. patients present with hyperchromic heterochromia.

• Racial Melanosis|BCEM|Benign Conjunctival Epithelial Melanosis|CAM|Complexion-Associated Melanosis|Conjunctival Hypermelanosis|Primary Conjunctival Hypermelanosis

  a benign conjunctival finding noted especially among darker pigmented individuals. while it is typically found perilimbally and bilaterally, it can also cover the conjunctivae extensively and may present asymmetrically. the flat, non-cystic pigmentation may increase in size with age. it is rare to have this finding evolve into conjunctival melanoma.

• Transient Neonatal Pustular Melanosis

  a benign, self-limited eruption of vesicles, pustules and macules seen in newborns. the fluid-filled lesions typically rupture and resolve within 48 hours while the macular lesions may persist for months.

MS-DRG Mapping for ICD-10-CM Code L81.4

Diagnosis-Related Groups (DRGs) are used to classify hospital cases for billing and healthcare management. They help standardize how hospitals and other providers are reimbursed for inpatient care. Patients are grouped based on their principal diagnosis into broader categories called Major Diagnostic Categories (MDCs).

Once assigned to a DRG, the hospital receives a set payment for the patient’s care, regardless of the actual services provided. This fixed rate is intended to cover the typical cost of treating patients within that group. The payment amount depends on the DRG's relative weight, which reflects the expected complexity and cost of care based on the severity of the patient’s condition.

Diagnostic related groups encourage healthcare providers to focus on quality and efficiency in patient care while managing costs effectively. The diagnosis code is present in the following groups for version MS-DRG V42.0 applicable from 10/01/2024 through 09/30/2025.

Convert L81.4 to ICD-9-CM

Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.

Patient Education

Skin Pigmentation Disorders

Pigmentation means coloring. Skin pigmentation disorders affect the color of your skin. Your skin gets its color from a pigment called melanin. Special cells in the skin make melanin. When these cells become damaged or unhealthy, it affects melanin production. Some pigmentation disorders affect just patches of skin. Others affect your entire body.

If your body makes too much melanin, your skin gets darker. Pregnancy, Addison's disease, and sun exposure all can make your skin darker. If your body makes too little melanin, your skin gets lighter. Vitiligo is a condition that causes patches of light skin. Albinism is a genetic condition affecting a person's skin. A person with albinism may have no color, lighter than normal skin color, or patchy missing skin color. Infections, blisters and burns can also cause lighter skin.

[Learn More in MedlinePlus]

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.