2026 ICD-10-CM Diagnosis Code J98.51Mediastinitis
ICD-10-CM Codes›J00–J99›J96-J99›J98
- Billable — Valid for Submission
- MCC — Major Complication or Comorbidity
- Not Chronic
J98.51 is a billable ICD-10-CM diagnosis code for mediastinitis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 177 through 179, 791, 793. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 1 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Mediastinal disorders.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Acute mediastinitis
- Classical histoplasmosis mediastinal granuloma
- Drug-induced granulomatous mediastinitis
- Familial fibrous mediastinitis
- Fibrous mediastinitis caused by radiation
- Granulomatous mediastinitis
- Hemorrhagic mediastinitis
- Infection of lower respiratory tract and mediastinum
- Infectious fibrous mediastinitis
- Infectious granulomatous mediastinitis
- Infectious mediastinitis
- Inflammatory disorder of mediastinum
- Pulmonary venous hypertension due to compression of pulmonary great vein
- Pulmonary venous hypertension due to compression of pulmonary great vein by sclerosing mediastinitis
- Sclerosing mediastinitis
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Code First
- underlying condition, if applicable, such as postoperative mediastinitis T81
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Mediastinitis
inflammation of the mediastinum, the area between the pleural sacs.Infectious Mediastinitis|Mediastinal infection
an acute or chronic infectious process affecting the mediastinum.Mediastinitis
an inflammatory process affecting the mediastinum.Radiation-Induced Fibrous Mediastinitis
fibrous mediastinitis arising due to radiation therapy.
Convert J98.51 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code History & ChangesHistory
Replacement J98.51 replaces the following previously assigned code(s):
- J98.5 - Diseases of mediastinum, not elsewhere classified
Questions About J98.51Overview
What is the ICD-10 code for mediastinitis?
The ICD-10-CM code for mediastinitis is J98.51 (sometimes written as J9851). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Is J98.51 (Diseases of mediastinum, not elsewhere classified) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report mediastinitis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does J98.51 group to?
When mediastinitis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 177, 178, 179, 791, 793, with relative weights from 0.7550 to 4.1696 depending on complications. Higher weights mean higher Medicare reimbursement.
Is J98.51 a CC or MCC?
CMS lists J98.51 as an MCC (major complication or comorbidity) for FY 2026. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 1 closely related codes in its exclusion list.
What is the ICD-9 equivalent of J98.51?
Under the General Equivalence Mappings, mediastinitis converts to ICD-9-CM 519.2 (mediastinitis). The mapping is a direct match.