2025 ICD-10-CM Diagnosis Code K22.0

Approximate Synonyms

The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.

Clinical Classification

Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.

They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.

Clinical Information

• Thyroid Hormone Resistance Syndrome

  an inherited autosomal recessive trait, characterized by peripheral resistance to thyroid hormones and the resulting elevation in serum levels of thyroxine and triiodothyronine. this syndrome is caused by mutations of gene thrb encoding the thyroid hormone receptors beta in target cells. hypothyroidism in these patients is partly overcome by the increased thyroid hormone levels.

• Moyamoya Disease

  a noninflammatory, progressive occlusion of the intracranial carotid arteries and the formation of netlike collateral arteries arising from the circle of willis. cerebral angiogram shows the puff-of-smoke (moyamoya) collaterals at the base of the brain. it is characterized by endothelial hyperplasia and fibrosis with thickening of arterial walls. this disease primarily affects children but can also occur in adults.

• AAAS wt Allele|AAA|AAASb|ADRACALA|ADRACALIN|ALADIN|Achalasia, Adrenocortical Insufficiency, Alacrimia (Allgrove, Triple-A) Gene|Achalasia, Adrenocortical Insufficiency, Alacrimia Gene|Aladin WD Repeat Nucleoporin wt Allele|Allgrove, Triple-A Gene|GL003

  human aaas wild-type allele is located in the vicinity of 12q13.13 and is approximately 17 kb in length. this allele, which encodes aladin protein, is involved in peripheral and central nervous system development and mitotic spindle formation. mutations in the gene are associated with achalasia-addisonianism-alacrima syndrome (allgrove or triple-a syndrome).

• Achalasia

  failure of the smooth muscle fibers of the gastrointestinal tract to relax at any one point of junction of one part with another.

• Esophageal Achalasia|Achalasia Cardia|Achalasia of Cardia

  a finding indicating the lack of adequate relaxation of the lower esophageal sphincter resulting in difficulty swallowing food.

• Triple A Syndrome|3A syndrome|Achalasia-Addisonianism-Alacrima Syndrome|Allgrove Syndrome|Allgrove Syndrome|Triple-A syndrome

  an autosomal recessive condition caused by mutation(s) in the aaas gene encoding the protein aladin, and characterized by primary adrenal insufficiency, esophageal dysmotility, and absence of tear production.

• Moyamoya Disease

  a rare inherited vascular disorder characterized by constriction of arteries at the base of the brain, resulting in the formation of collateral circulation in order to compensate for the constriction. the name "moyamoya" in japanese means "puff of smoke" and derives from the characteristic radiographic appearance of the collateral vessels.

• Moyamoya Disease 2|MYMY2

  an autosomally inherited subtype of moyamoya disease often presenting in childhood caused by mutation(s) in the rnf213 gene, encoding e3 ubiquitin-protein ligase rnf213.

• RNF213 wt Allele|ALK Lymphoma Oligomerization Partner on Chromosome 17 Gene|ALO17|C17orf27|Chromosome 17 Open Reading Frame 27 Gene|DKFZp762N1115|FLJ13051|KIAA1554|KIAA1618|MGC46622|MGC9929|MYMY2|MYSTR|Moyamoya Disease 2 Gene|NET57|Ring Finger Protein 213 wt Allele|hCG_1812857

  human rnf213 wild-type allele is located in the vicinity of 17q25.3 and is approximately 135 kb in length. this allele, which encodes e3 ubiquitin-protein ligase rnf213 protein, may play a role in the regulation of protein ubiquitination. a chromosomal translocation t(2;17)(p23;q25) of this gene with the alk gene is associated with anaplastic large cell lymphoma.

• Megaesophagus

  an abnormal dilation of the esophagus not due to obstruction.

• Alacrima, Achalasia, and Impaired Intellectual Development Syndrome|AAMR

  an autosomal recessive condition caused by mutation(s) in the gmppa gene, encoding mannose-1-phosphate guanyltransferase alpha. it is characterized by alacrima, achalasia, and impaired intellectual development.

MS-DRG Mapping for ICD-10-CM Code K22.0

Diagnosis-Related Groups (DRGs) are used to classify hospital cases for billing and healthcare management. They help standardize how hospitals and other providers are reimbursed for inpatient care. Patients are grouped based on their principal diagnosis into broader categories called Major Diagnostic Categories (MDCs).

Once assigned to a DRG, the hospital receives a set payment for the patient’s care, regardless of the actual services provided. This fixed rate is intended to cover the typical cost of treating patients within that group. The payment amount depends on the DRG's relative weight, which reflects the expected complexity and cost of care based on the severity of the patient’s condition.

Diagnostic related groups encourage healthcare providers to focus on quality and efficiency in patient care while managing costs effectively. The diagnosis code is present in the following groups for version MS-DRG V42.0 applicable from 10/01/2024 through 09/30/2025.

Convert K22.0 to ICD-9-CM

Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.

Patient Education

Esophagus Disorders

The esophagus is the muscular tube that carries food and liquids from your mouth to the stomach. You may not be aware of your esophagus until you swallow something too large, too hot, or too cold. You may also notice it when something is wrong. You may feel pain or have trouble swallowing.

The most common problem with the esophagus is GERD (gastroesophageal reflux disease). With GERD, a muscle at the end of your esophagus does not close properly. This allows stomach contents to leak back, or reflux, into the esophagus and irritate it. Over time, GERD can cause damage to the esophagus.

Other problems include heartburn, cancer, and eosinophilic esophagitis. Doctors may use various tests to make a diagnosis. These include imaging tests, an upper endoscopy, and a biopsy.

Treatment depends on the problem. Some problems get better with over-the-counter medicines or changes in diet. Others may need prescription medicines or surgery.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

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Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.