2025 ICD-10-CM Diagnosis Code C41.2

Malignant neoplasm of vertebral column

ICD-10-CM Code:
C41.2
ICD-10 Code for:
Malignant neoplasm of vertebral column
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Chronic
Code Navigator:

C41.2 is a billable diagnosis code used to specify a medical diagnosis of malignant neoplasm of vertebral column. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2024 through September 30, 2025.

The following anatomical sites found in the Table of Neoplasms reference this diagnosis code given the correct histological behavior: Neoplasm, neoplastic atlas ; Neoplasm, neoplastic bone (periosteum) atlas ; Neoplasm, neoplastic bone (periosteum) axis ; Neoplasm, neoplastic bone (periosteum) back NEC ; Neoplasm, neoplastic bone (periosteum) intervertebral cartilage or disc ; Neoplasm, neoplastic bone (periosteum) spine, spinal (column) ; Neoplasm, neoplastic bone (periosteum) vertebra (column) ; etc

Code Classification

  • Neoplasms
    C00–D49
    • Malignant neoplasms of bone and articular cartilage
      C40-C41
      • Malignant neoplasm of bone and articular cartilage of other and unspecified sites
        C41

Approximate Synonyms

The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.

  • Chondrosarcoma of vertebral column
  • Chordoma
  • Chordoma of cervical spine
  • Chordoma of lumbar spine
  • Chordoma of thoracic spine
  • Chordoma of vertebral column
  • Dedifferentiated chordoma
  • Malignant neoplasm of cervical vertebra
  • Malignant neoplasm of lumbar vertebra
  • Malignant neoplasm of thoracic vertebra
  • Malignant neoplasm of thoracic vertebral column
  • Malignant neoplasm of vertebra
  • Malignant neoplasm of vertebral column
  • Malignant neoplasm of vertebral column region
  • Mass of thoracic vertebrae
  • Neoplasm of cervical vertebra
  • Neoplasm of lumbar vertebra
  • Neoplasm of thoracic vertebra
  • Osteosarcoma of articular cartilage of vertebra
  • Osteosarcoma of bone of vertebra
  • Poorly differentiated chordoma
  • Primary chondrosarcoma of vertebral column
  • Primary chordoma
  • Primary chordoma of cervical spine
  • Primary chordoma of lumbar spine
  • Primary chordoma of thoracic spine
  • Primary chordoma of vertebral column
  • Primary Ewing sarcoma of bone of spine
  • Primary malignant neoplasm of cervical vertebral column
  • Primary malignant neoplasm of lumbar vertebral column
  • Primary malignant neoplasm of thoracic vertebral column
  • Primary malignant neoplasm of vertebral column
  • Primary osteosarcoma of articular cartilage of vertebra
  • Primary osteosarcoma of bone of vertebra
  • Primary osteosarcoma of vertebral column
  • Sarcoma of vertebra

Clinical Classification

Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.

They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.

Bone cancer

CCSR Code: NEO023

Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.

Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.

Clinical Information

  • Nucleus Pulposus

    fibrocartilage inner core of the intervertebral disc. prolapsed or bulged nucleus pulposus leads to intervertebral disc displacement while proliferation of cells in the nucleus pulposus is associated with intervertebral disc degeneration.
  • Chordoma

    a malignant tumor arising from the embryonic remains of the notochord. it is also called chordocarcinoma, chordoepithelioma, and notochordoma. (dorland, 27th ed)
  • Poorly Differentiated Chordoma

    a rare, aggressive type of chordoma characterized by loss of smarcb1 expression. it affects children and occasionally young adults. females are affected twice as frequently as males. it usually arises in the axial skeleton. it is composed of sheets or nests of malignant epithelioid cells with abundant eosinophilic cytoplasm. the prognosis is poor.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • malignant neoplasm of sacrum and coccyx C41.4

Convert C41.2 to ICD-9-CM

Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.

Malig neo vertebrae

ICD-9-CM: 170.2

This is a direct match with no additional mapping qualifiers. The absence of a flag generally means the mapping is considered exact or precise. In other words, the ICD-10 code maps cleanly to the ICD-9 code without qualification, approximation, or needing multiple codes.

Table of Neoplasms

This code is referenced in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Neoplasm, neoplastic Malignant
Primary
Malignant
Secondary
CaInSitu Benign Uncertain
Behavior
Unspecified
Behavior
»Neoplasm, neoplastic
  »atlas
C41.2C79.51 D16.6D48.0D49.2
»Neoplasm, neoplastic
  »bone (periosteum)
    »atlas
C41.2C79.51 D16.6D48.0D49.2
»Neoplasm, neoplastic
  »bone (periosteum)
    »axis
C41.2C79.51 D16.6D48.0D49.2
»Neoplasm, neoplastic
  »bone (periosteum)
    »back NEC
C41.2C79.51 D16.6D48.0D49.2
»Neoplasm, neoplastic
  »bone (periosteum)
    »intervertebral cartilage or disc
C41.2C79.51 D16.6D48.0D49.2
»Neoplasm, neoplastic
  »bone (periosteum)
    »spine, spinal (column)
C41.2C79.51 D16.6D48.0D49.2
»Neoplasm, neoplastic
  »bone (periosteum)
    »vertebra (column)
C41.2C79.51 D16.6D48.0D49.2
»Neoplasm, neoplastic
  »cartilage (articular) (joint) NEC [See Also: Neoplasm, bone]
    »intervertebral
C41.2C79.51 D16.6D48.0D49.2
»Neoplasm, neoplastic
  »disc, intervertebral
C41.2C79.51 D16.6D48.0D49.2
»Neoplasm, neoplastic
  »intervertebral cartilage or disc
C41.2C79.51 D16.6D48.0D49.2
»Neoplasm, neoplastic
  »nucleus pulposus
C41.2C79.51 D16.6D48.0D49.2
»Neoplasm, neoplastic
  »spine, spinal (column)
C41.2C79.51 D16.6D48.0D49.2
»Neoplasm, neoplastic
  »spine, spinal (column)
    »lumbosacral
C41.2C79.51 D16.6D48.0D49.2
»Neoplasm, neoplastic
  »vertebra (column)
C41.2C79.51 D16.6D48.0D49.2

Patient Education


Bone Cancer

Cancer that starts in a bone is uncommon. Cancer that has spread to the bone from another part of the body is more common.

There are three types of bone cancer:

  • Osteosarcoma - occurs most often between ages 10 and 19. It is more common in the knee and upper arm.
  • Chondrosarcoma - starts in cartilage, usually after age 40
  • Ewing's sarcoma - occurs most often in children and teens under 19. It is more common in boys than girls.

The most common symptom of bone cancer is pain. Other symptoms vary, depending on the location and size of the cancer. Surgery is often the main treatment for bone cancer. Other treatments may include amputation, chemotherapy, and radiation therapy. Because bone cancer can come back after treatment, regular follow-up visits are important.

NIH: National Cancer Institute


[Learn More in MedlinePlus]

Chordoma

A chordoma is a rare type of cancerous tumor that can occur anywhere along the spine, from the base of the skull to the tailbone. Chordomas grow slowly, gradually extending into the bone and soft tissue around them. They often recur after treatment, and in about 40 percent of cases the cancer spreads (metastasizes) to other areas of the body, such as the lungs.

Approximately half of all chordomas occur at the base of the spine (sacrum), about one third occur in the base of the skull (occiput), and the rest occur in the cervical (neck), thoracic (upper back), or lumbar (lower back) vertebrae of the spine. As the chordoma grows, it puts pressure on the adjacent areas of the brain or spinal cord, leading to the signs and symptoms of the disorder. A chordoma anywhere along the spine may cause pain, weakness, or numbness in the back, arms, or legs. A chordoma at the base of the skull (occipital chordoma) may lead to double vision (diplopia) and headaches. A chordoma that occurs in the tailbone (coccygeal chordoma) may result in a lump large enough to be felt through the skin and may cause problems with bladder or bowel function.

Chordomas typically occur in adults between ages 40 and 70. About 5 percent of chordomas are diagnosed in children. For reasons that are unclear, males are affected about twice as often as females.


[Learn More in MedlinePlus]

Primary Bone Cancer

Learn about the types of bone tumors and the methods used to diagnose and treat cancers that form from bone tissue.
[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.