3E043GRIntroduction of Other Therapeutic Monoclonal Antibody into Central Vein, Percutaneous Approach

Administration›Physiological Systems and Anatomical Regions›Introduction

Billable / Specific Code

ICD-10-PCS 3E043GR

CMS Source: FY 2026 ICD-10-PCS dataset. Effective Oct 1, 2025 – Sep 30, 2026.

3E043GR is a billable ICD-10-PCS procedure code for Introduction of Other Therapeutic Monoclonal Antibody into Central Vein, Percutaneous Approach. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

Code Identity

ICD-10-PCS Code

3E043GR

Billable Status

Yes — Valid for Submission

Code Describes

Introduction of Other Therapeutic Monoclonal Antibody into Central Vein, Percutaneous Approach

Parent Code

3E0

Short Description

Introduce Oth Rx Moncln Ab in Central Vein, Perc

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

Position	Designation	Value	Meaning
1	Section	3	Administration
2	Body System	E	Physiological Systems and Anatomical Regions
3	Operation	0	Introduction
4	BodySystem/Region	4	Central Vein
5	Approach	3	Percutaneous
6	Substance	G	Other Therapeutic Substance
7	Qualifier	R	Other Therapeutic Monoclonal Antibody

Code History

Replaces previously assigned code(s):

XW043A3 — Introduce Bezlotoxumab in Central Vein, Perc, New Tech 3

Replaced in the FY 2026 code set by:

XW043MA — Introduce Emapalumab-lzsg in Central Vein, Perc, New Tech 1

Similar Procedure Codes

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Questions About 3E043GR

Is 3E043GR a billable code?

Yes. 3E043GR is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of Other Therapeutic Monoclonal Antibody into Central Vein, Percutaneous Approach on inpatient claims from October 1, 2025 through September 30, 2026.

What do the characters in 3E043GR mean?

3E043GR breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character 4 is the BodySystem/Region (Central Vein); the 5th character 3 is the Approach (Percutaneous); the 6th character G is the Substance (Other Therapeutic Substance); the 7th character R is the Qualifier (Other Therapeutic Monoclonal Antibody).