3E04329Introduction of Other Anti-infective into Central Vein, Percutaneous Approach

Administration›Physiological Systems and Anatomical Regions›Introduction

Billable / Specific Code

ICD-10-PCS 3E04329

CMS Source: FY 2026 ICD-10-PCS dataset. Effective Oct 1, 2025 – Sep 30, 2026.

3E04329 is a billable ICD-10-PCS procedure code for Introduction of Other Anti-infective into Central Vein, Percutaneous Approach. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

Code Identity

ICD-10-PCS Code

3E04329

Billable Status

Yes — Valid for Submission

Code Describes

Introduction of Other Anti-infective into Central Vein, Percutaneous Approach

Parent Code

3E0

Short Description

Introduce Oth Anti-infect in Central Vein, Perc

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

Position	Designation	Value	Meaning
1	Section	3	Administration
2	Body System	E	Physiological Systems and Anatomical Regions
3	Operation	0	Introduction
4	BodySystem/Region	4	Central Vein
5	Approach	3	Percutaneous
6	Substance	2	Anti-infective
7	Qualifier	9	Other Anti-infective

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for 3E04329 under the General Equivalence Mappings.

99.21

Approximate match.

Code History

Replaced in the FY 2026 code set by:

XW0434A — Introduce Cefe-taniborb in Central Vein, Perc, New Tech 10
XW0435A — Introduce Cefto Medocaril in Central Vein, Perc, New Tech 1
XW04366 — Introduce Lefamulin in Central Vein, Perc, New Tech 6
XW04396 — Introduce Ceftoloz/Tazobac in Central Vein, Perc, New Tech 6
XW043A6 — Introduce Cefiderocol in Central Vein, Perc, New Tech 6
XW043B6 — Introduce Omadacycline in Central Vein, Perc, New Tech 6
XW043E5 — Introduce Remdesivir in Central Vein, Perc, New Tech 5
XW043G4 — Introduce Plazomicin in Central Vein, Perc, New Tech 4
XW043K5 — Introduce Fosfomycin in Central Vein, Perc, New Tech 5
XW043K9 — Introduce Sulbac-Durlobac in Central Vein, Perc, New Tech 9
XW043N5 — Introduce Merop-vaborbct in Central Vein, Perc, New Tech 5
XW043PB — Introduce Aztreonm-avbact in Central Vein, Perc, New Tech 1
XW043R9 — Introduce Rezafungin in Central Vein, Perc, New Tech 9
XW043U5 — Introduce IMI/REL in Central Vein, Perc, New Tech 5
XW043WB — Introduce Fosfomycin in Central Vein, Perc, New Tech 11

Similar Procedure Codes

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Questions About 3E04329

Is 3E04329 a billable code?

Yes. 3E04329 is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of Other Anti-infective into Central Vein, Percutaneous Approach on inpatient claims from October 1, 2025 through September 30, 2026.

What do the characters in 3E04329 mean?

3E04329 breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character 4 is the BodySystem/Region (Central Vein); the 5th character 3 is the Approach (Percutaneous); the 6th character 2 is the Substance (Anti-infective); the 7th character 9 is the Qualifier (Other Anti-infective).

What is the ICD-9-PCS equivalent of 3E04329?

Under the General Equivalence Mappings, Introduction of Other Anti-infective into Central Vein, Percutaneous Approach crosswalks to ICD-9-PCS 99.21. The mapping is approximate, so confirm it fits the documentation.