3E04002Introduction of High-dose Interleukin-2 into Central Vein, Open Approach

  • Billable / Specific Code
ICD-10-PCS 3E04002
CMS Source: FY 2026 ICD-10-PCS dataset. Effective Oct 1, 2025 – Sep 30, 2026.FacebookXLinkedInPrint

3E04002 is a billable ICD-10-PCS procedure code for Introduction of High-dose Interleukin-2 into Central Vein, Open Approach. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRGs 837, 838. The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

Code Identity

ICD-10-PCS Code
3E04002
Billable Status
Yes — Valid for Submission
Code Describes
Introduction of High-dose Interleukin-2 into Central Vein, Open Approach
Parent Code
Short Description
Introduce of High dose IL-2 into Central Vein, Open Approac

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

PositionDesignationValueMeaning
1Section3Administration
2Body SystemEPhysiological Systems and Anatomical Regions
3Operation0Introduction
4BodySystem/Region4Central Vein
5Approach0Open
6Substance0Antineoplastic
7Qualifier2High-dose Interleukin-2

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for 3E04002 under the General Equivalence Mappings.

15
Approximate match.

Similar Procedure Codes

Questions About 3E04002

Is 3E04002 a billable code?

Yes. 3E04002 is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of High-dose Interleukin-2 into Central Vein, Open Approach on inpatient claims from October 1, 2025 through September 30, 2026.

What do the characters in 3E04002 mean?

3E04002 breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character 4 is the BodySystem/Region (Central Vein); the 5th character 0 is the Approach (Open); the 6th character 0 is the Substance (Antineoplastic); the 7th character 2 is the Qualifier (High-dose Interleukin-2).

What MS-DRG does 3E04002 group to?

On an inpatient stay, Introduction of High-dose Interleukin-2 into Central Vein, Open Approach maps to MS-DRGs 837, 838, with relative weights from 2.0874 to 4.8043. The MS-DRG sets the fixed Medicare payment for the stay.

What is the ICD-9-PCS equivalent of 3E04002?

Under the General Equivalence Mappings, Introduction of High-dose Interleukin-2 into Central Vein, Open Approach crosswalks to ICD-9-PCS 15. The mapping is approximate, so confirm it fits the documentation.