3E043GNIntroduction of Blood Brain Barrier Disruption Substance into Central Vein, Percutaneous Approach

Administration›Physiological Systems and Anatomical Regions›Introduction

Billable / Specific Code

ICD-10-PCS 3E043GN

CMS Source: FY 2026 ICD-10-PCS dataset. Effective Oct 1, 2025 – Sep 30, 2026.

3E043GN is a billable ICD-10-PCS procedure code for Introduction of Blood Brain Barrier Disruption Substance into Central Vein, Percutaneous Approach. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

Code Identity

ICD-10-PCS Code

3E043GN

Billable Status

Yes — Valid for Submission

Code Describes

Introduction of Blood Brain Barrier Disruption Substance into Central Vein, Percutaneous Approach

Parent Code

3E0

Short Description

Introduce of BBBD Substance into Central Vein, Perc Approac

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

Position	Designation	Value	Meaning
1	Section	3	Administration
2	Body System	E	Physiological Systems and Anatomical Regions
3	Operation	0	Introduction
4	BodySystem/Region	4	Central Vein
5	Approach	3	Percutaneous
6	Substance	G	Other Therapeutic Substance
7	Qualifier	N	Blood Brain Barrier Disruption

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for 3E043GN under the General Equivalence Mappings.

Approximate match.

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Questions About 3E043GN

Is 3E043GN a billable code?

Yes. 3E043GN is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of Blood Brain Barrier Disruption Substance into Central Vein, Percutaneous Approach on inpatient claims from October 1, 2025 through September 30, 2026.

What do the characters in 3E043GN mean?

3E043GN breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character 4 is the BodySystem/Region (Central Vein); the 5th character 3 is the Approach (Percutaneous); the 6th character G is the Substance (Other Therapeutic Substance); the 7th character N is the Qualifier (Blood Brain Barrier Disruption).

What is the ICD-9-PCS equivalent of 3E043GN?

Under the General Equivalence Mappings, Introduction of Blood Brain Barrier Disruption Substance into Central Vein, Percutaneous Approach crosswalks to ICD-9-PCS 19. The mapping is approximate, so confirm it fits the documentation.