3E00XTZIntroduction of Destructive Agent into Skin and Mucous Membranes, External Approach

  • Billable / Specific Code
ICD-10-PCS 3E00XTZ
CMS Source: FY 2027 ICD-10-PCS dataset. Effective Oct 1, 2026 – Sep 30, 2027.FacebookXLinkedInPrint

3E00XTZ is a billable ICD-10-PCS procedure code for Introduction of Destructive Agent into Skin and Mucous Membranes, External Approach. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027). The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products. In AHRQ's Clinical Classifications Software (CCSR), this procedure falls under Administration of therapeutic substances, NEC.

Code Identity

ICD-10-PCS Code
3E00XTZ
Billable Status
Yes — Valid for Submission
Code Describes
Introduction of Destructive Agent into Skin and Mucous Membranes, External Approach
Short Description
Introduce Destr Agent in Skin/Mucous Mem, Extern
Parent Code

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

PositionDesignationValueMeaning
1Section3Administration
2Body SystemEPhysiological Systems and Anatomical Regions
3Operation0Introduction
4BodySystem/Region0Skin and Mucous Membranes
5ApproachXExternal
6SubstanceTDestructive Agent
7QualifierZNo Qualifier

In the ICD-10-PCS Alphabetic Index

These FY 2027 ICD-10-PCS Alphabetic Index entries lead to this code:

Chemosurgery, Skin
Direct entry for this code
Introduction of substance in or on, Skin, Destructive Agent
Direct entry for this code
Introduction of substance in or on, Mucous Membrane, Destructive Agent
Direct entry for this code
Tattooing, Skin
Leads to this code's table
Sclerotherapy, via injection of sclerosing agent
Anatomy or device term that leads here

To code chemosurgery of the skin, open the FY 2027 ICD-10-PCS Alphabetic Index at Chemosurgery, then the subterm Skin. The entry lists 3E00XTZ directly as a complete, billable code.

Browse the full ICD-10-PCS Alphabetic Index →

Clinical Classification (CCSR)

AHRQ groups this procedure code into these clinical categories.

ADM021
Administration of therapeutic substances, NEC
Clinical domain: Administration of Therapeutic Substances

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for this code under the General Equivalence Mappings.

86.24
Chemosurgery of skin
Approximate match.

Similar Procedure Codes

Questions About 3E00XTZ

Is 3E00XTZ a billable code?

Yes. This is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of Destructive Agent into Skin and Mucous Membranes, External Approach on inpatient claims from October 1, 2026 through September 30, 2027.

What is the ICD-10-PCS code for chemosurgery of the skin?

The FY 2027 ICD-10-PCS Alphabetic Index entry Chemosurgery, Skin is a direct entry for 3E00XTZ, Introduction of Destructive Agent into Skin and Mucous Membranes, External Approach, billable on inpatient claims from October 1, 2026 through September 30, 2027.

What do the characters in 3E00XTZ mean?

The code breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character 0 is the BodySystem/Region (Skin and Mucous Membranes); the 5th character X is the Approach (External); the 6th character T is the Substance (Destructive Agent); the 7th character Z is the Qualifier (No Qualifier).

What is the ICD-9-PCS equivalent of 3E00XTZ?

Under the General Equivalence Mappings, Introduction of Destructive Agent into Skin and Mucous Membranes, External Approach crosswalks to ICD-9-PCS 86.24 (Chemosurgery of skin). The mapping is approximate, so confirm it fits the documentation.