3E00XGCIntroduction of Other Therapeutic Substance into Skin and Mucous Membranes, External Approach

  • Billable / Specific Code
ICD-10-PCS 3E00XGC
CMS Source: FY 2026 ICD-10-PCS dataset. Effective Oct 1, 2025 – Sep 30, 2026.FacebookXLinkedInPrint

3E00XGC is a billable ICD-10-PCS procedure code for Introduction of Other Therapeutic Substance into Skin and Mucous Membranes, External Approach. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

Code Identity

ICD-10-PCS Code
3E00XGC
Billable Status
Yes — Valid for Submission
Code Describes
Introduction of Other Therapeutic Substance into Skin and Mucous Membranes, External Approach
Parent Code
Short Description
Introduce Oth Therap Subst in Skin/Mucous Mem, Extern

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

PositionDesignationValueMeaning
1Section3Administration
2Body SystemEPhysiological Systems and Anatomical Regions
3Operation0Introduction
4BodySystem/Region0Skin and Mucous Membranes
5ApproachXExternal
6SubstanceGOther Therapeutic Substance
7QualifierCOther Substance

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for 3E00XGC under the General Equivalence Mappings.

85.92
Approximate match.
99.27
Approximate match.
99.86
Approximate match.

Code History

Replaced in the FY 2026 code set by:
  • XW00X27 — Introduce Bromln Proteolyt Enzy in Skin, Extern, New Tech 7

Similar Procedure Codes

Questions About 3E00XGC

Is 3E00XGC a billable code?

Yes. 3E00XGC is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of Other Therapeutic Substance into Skin and Mucous Membranes, External Approach on inpatient claims from October 1, 2025 through September 30, 2026.

What do the characters in 3E00XGC mean?

3E00XGC breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character 0 is the BodySystem/Region (Skin and Mucous Membranes); the 5th character X is the Approach (External); the 6th character G is the Substance (Other Therapeutic Substance); the 7th character C is the Qualifier (Other Substance).

What is the ICD-9-PCS equivalent of 3E00XGC?

Under the General Equivalence Mappings, Introduction of Other Therapeutic Substance into Skin and Mucous Membranes, External Approach crosswalks to ICD-9-PCS 85.92, 99.27, and 99.86. The mapping is approximate, so confirm it fits the documentation.