MS-DRG · FY 2026 v43.0

MS-DRG 583 – Mastectomy for Malignancy without CC/MCC

A Surgical DRG in MDC 09 (Diseases & Disorders of the Skin, Subcutaneous Tissue & Breast). Inpatient cases group to DRG 583 when one of the 61 ICD-10-PCS operating-room procedures listed below is reported with a qualifying principal diagnosis. Its FY 2026 relative weight is 1.7244 with a geometric mean length of stay of 1.7 days.

Surgical DRG – assigned by operating-room procedure✓ Official CMS v43.0 dataset
1.7244
Relative Weight
1.7
Geometric Mean LOS (days)
2.1
Arithmetic Mean LOS (days)
74
Diagnosis Codes
61
Procedure Codes

Severity family

DRG 582with CC/MCCWeight 1.9266 · GMLOS 2.6 daysDRG 583without CC/MCCWeight 1.7244 · GMLOS 1.7 days
How a case is assigned to DRG 583

The grouper first assigns the case to MDC 09 from the principal diagnosis, then matches a qualifying operating-room procedure from the ICD-10-PCS list below (this is a Surgical DRG), then applies the severity split from secondary diagnoses: with CC/MCC → 582; without CC/MCC → 583.

ICD-10-PCS

Procedure Codes 61 codes · 16 categories

61 of 61 shown
07T5 Lymphatic and Hemic Systems, Resection1 code
  • 07T50ZZ Resection of Right Axillary Lymphatic, Open Approach
07T6 Lymphatic and Hemic Systems, Resection1 code
  • 07T60ZZ Resection of Left Axillary Lymphatic, Open Approach
0H0V Skin and Breast, Alteration1 code
  • 0H0V0JZ Alteration of Bilateral Breast with Synthetic Substitute, Open Approach
0HBT Skin and Breast, Excision2 codes
  • 0HBT0ZZ Excision of Right Breast, Open Approach
  • 0HBT3ZZ Excision of Right Breast, Percutaneous Approach
0HBU Skin and Breast, Excision2 codes
  • 0HBU0ZZ Excision of Left Breast, Open Approach
  • 0HBU3ZZ Excision of Left Breast, Percutaneous Approach
0HBV Skin and Breast, Excision2 codes
  • 0HBV0ZZ Excision of Bilateral Breast, Open Approach
  • 0HBV3ZZ Excision of Bilateral Breast, Percutaneous Approach
0HRT Skin and Breast, Replacement10 codes
  • 0HRT075 Replacement of Right Breast using Latissimus Dorsi Myocutaneous Flap, Open Approach
  • 0HRT076 Replacement of Right Breast using Transverse Rectus Abdominis Myocutaneous Flap, Open Approach
  • 0HRT077 Replacement of Right Breast using Deep Inferior Epigastric Artery Perforator Flap, Open Approach
  • 0HRT078 Replacement of Right Breast using Superficial Inferior Epigastric Artery Flap, Open Approach
  • 0HRT079 Replacement of Right Breast using Gluteal Artery Perforator Flap, Open Approach
  • 0HRT07B Replacement of Right Breast using Lumbar Artery Perforator Flap, Open Approach
  • 0HRT07Z Replacement of Right Breast with Autologous Tissue Substitute, Open Approach
  • 0HRT0JZ Replacement of Right Breast with Synthetic Substitute, Open Approach
  • 0HRT0KZ Replacement of Right Breast with Nonautologous Tissue Substitute, Open Approach
  • 0HRT3JZ Replacement of Right Breast with Synthetic Substitute, Percutaneous Approach
0HRU Skin and Breast, Replacement10 codes
  • 0HRU075 Replacement of Left Breast using Latissimus Dorsi Myocutaneous Flap, Open Approach
  • 0HRU076 Replacement of Left Breast using Transverse Rectus Abdominis Myocutaneous Flap, Open Approach
  • 0HRU077 Replacement of Left Breast using Deep Inferior Epigastric Artery Perforator Flap, Open Approach
  • 0HRU078 Replacement of Left Breast using Superficial Inferior Epigastric Artery Flap, Open Approach
  • 0HRU079 Replacement of Left Breast using Gluteal Artery Perforator Flap, Open Approach
  • 0HRU07B Replacement of Left Breast using Lumbar Artery Perforator Flap, Open Approach
  • 0HRU07Z Replacement of Left Breast with Autologous Tissue Substitute, Open Approach
  • 0HRU0JZ Replacement of Left Breast with Synthetic Substitute, Open Approach
  • 0HRU0KZ Replacement of Left Breast with Nonautologous Tissue Substitute, Open Approach
  • 0HRU3JZ Replacement of Left Breast with Synthetic Substitute, Percutaneous Approach
0HRV Skin and Breast, Replacement9 codes
  • 0HRV075 Replacement of Bilateral Breast using Latissimus Dorsi Myocutaneous Flap, Open Approach
  • 0HRV076 Replacement of Bilateral Breast using Transverse Rectus Abdominis Myocutaneous Flap, Open Approach
  • 0HRV077 Replacement of Bilateral Breast using Deep Inferior Epigastric Artery Perforator Flap, Open Approach
  • 0HRV078 Replacement of Bilateral Breast using Superficial Inferior Epigastric Artery Flap, Open Approach
  • 0HRV079 Replacement of Bilateral Breast using Gluteal Artery Perforator Flap, Open Approach
  • 0HRV07B Replacement of Bilateral Breast using Lumbar Artery Perforator Flap, Open Approach
  • 0HRV07Z Replacement of Bilateral Breast with Autologous Tissue Substitute, Open Approach
  • 0HRV0JZ Replacement of Bilateral Breast with Synthetic Substitute, Open Approach
  • 0HRV3JZ Replacement of Bilateral Breast with Synthetic Substitute, Percutaneous Approach
0HTT Skin and Breast, Resection1 code
  • 0HTT0ZZ Resection of Right Breast, Open Approach
0HTU Skin and Breast, Resection1 code
  • 0HTU0ZZ Resection of Left Breast, Open Approach
0HTV Skin and Breast, Resection1 code
  • 0HTV0ZZ Resection of Bilateral Breast, Open Approach
0KXF Muscles, Transfer8 codes
  • 0KXF0Z5 Transfer Right Trunk Muscle, Latissimus Dorsi Myocutaneous Flap, Open Approach
  • 0KXF0Z7 Transfer Right Trunk Muscle, Deep Inferior Epigastric Artery Perforator Flap, Open Approach
  • 0KXF0Z8 Transfer Right Trunk Muscle, Superficial Inferior Epigastric Artery Flap, Open Approach
  • 0KXF0Z9 Transfer Right Trunk Muscle, Gluteal Artery Perforator Flap, Open Approach
  • 0KXF4Z5 Transfer Right Trunk Muscle, Latissimus Dorsi Myocutaneous Flap, Percutaneous Endoscopic Approach
  • 0KXF4Z7 Transfer Right Trunk Muscle, Deep Inferior Epigastric Artery Perforator Flap, Percutaneous Endoscopic Approach
  • 0KXF4Z8 Transfer Right Trunk Muscle, Superficial Inferior Epigastric Artery Flap, Percutaneous Endoscopic Approach
  • 0KXF4Z9 Transfer Right Trunk Muscle, Gluteal Artery Perforator Flap, Percutaneous Endoscopic Approach
0KXG Muscles, Transfer8 codes
  • 0KXG0Z5 Transfer Left Trunk Muscle, Latissimus Dorsi Myocutaneous Flap, Open Approach
  • 0KXG0Z7 Transfer Left Trunk Muscle, Deep Inferior Epigastric Artery Perforator Flap, Open Approach
  • 0KXG0Z8 Transfer Left Trunk Muscle, Superficial Inferior Epigastric Artery Flap, Open Approach
  • 0KXG0Z9 Transfer Left Trunk Muscle, Gluteal Artery Perforator Flap, Open Approach
  • 0KXG4Z5 Transfer Left Trunk Muscle, Latissimus Dorsi Myocutaneous Flap, Percutaneous Endoscopic Approach
  • 0KXG4Z7 Transfer Left Trunk Muscle, Deep Inferior Epigastric Artery Perforator Flap, Percutaneous Endoscopic Approach
  • 0KXG4Z8 Transfer Left Trunk Muscle, Superficial Inferior Epigastric Artery Flap, Percutaneous Endoscopic Approach
  • 0KXG4Z9 Transfer Left Trunk Muscle, Gluteal Artery Perforator Flap, Percutaneous Endoscopic Approach
0KXK Muscles, Transfer2 codes
  • 0KXK0Z6 Transfer Right Abdomen Muscle, Transverse Rectus Abdominis Myocutaneous Flap, Open Approach
  • 0KXK4Z6 Transfer Right Abdomen Muscle, Transverse Rectus Abdominis Myocutaneous Flap, Percutaneous Endoscopic Approach
0KXL Muscles, Transfer2 codes
  • 0KXL0Z6 Transfer Left Abdomen Muscle, Transverse Rectus Abdominis Myocutaneous Flap, Open Approach
  • 0KXL4Z6 Transfer Left Abdomen Muscle, Transverse Rectus Abdominis Myocutaneous Flap, Percutaneous Endoscopic Approach
ICD-10-CM

Qualifying Diagnosis Codes 74 codes · 4 categories

74 of 74 shown
C50 Malignant neoplasm of breast57 codes
  • C50.011 Malignant neoplasm of nipple and areola, right female breast
  • C50.012 Malignant neoplasm of nipple and areola, left female breast
  • C50.019 Malignant neoplasm of nipple and areola, unspecified female breast
  • C50.021 Malignant neoplasm of nipple and areola, right male breast
  • C50.022 Malignant neoplasm of nipple and areola, left male breast
  • C50.029 Malignant neoplasm of nipple and areola, unspecified male breast
  • C50.111 Malignant neoplasm of central portion of right female breast
  • C50.112 Malignant neoplasm of central portion of left female breast
  • C50.119 Malignant neoplasm of central portion of unspecified female breast
  • C50.121 Malignant neoplasm of central portion of right male breast
  • C50.122 Malignant neoplasm of central portion of left male breast
  • C50.129 Malignant neoplasm of central portion of unspecified male breast
  • C50.211 Malignant neoplasm of upper-inner quadrant of right female breast
  • C50.212 Malignant neoplasm of upper-inner quadrant of left female breast
  • C50.219 Malignant neoplasm of upper-inner quadrant of unspecified female breast
  • C50.221 Malignant neoplasm of upper-inner quadrant of right male breast
  • C50.222 Malignant neoplasm of upper-inner quadrant of left male breast
  • C50.229 Malignant neoplasm of upper-inner quadrant of unspecified male breast
  • C50.311 Malignant neoplasm of lower-inner quadrant of right female breast
  • C50.312 Malignant neoplasm of lower-inner quadrant of left female breast
  • C50.319 Malignant neoplasm of lower-inner quadrant of unspecified female breast
  • C50.321 Malignant neoplasm of lower-inner quadrant of right male breast
  • C50.322 Malignant neoplasm of lower-inner quadrant of left male breast
  • C50.329 Malignant neoplasm of lower-inner quadrant of unspecified male breast
  • C50.411 Malignant neoplasm of upper-outer quadrant of right female breast
  • C50.412 Malignant neoplasm of upper-outer quadrant of left female breast
  • C50.419 Malignant neoplasm of upper-outer quadrant of unspecified female breast
  • C50.421 Malignant neoplasm of upper-outer quadrant of right male breast
  • C50.422 Malignant neoplasm of upper-outer quadrant of left male breast
  • C50.429 Malignant neoplasm of upper-outer quadrant of unspecified male breast
  • C50.511 Malignant neoplasm of lower-outer quadrant of right female breast
  • C50.512 Malignant neoplasm of lower-outer quadrant of left female breast
  • C50.519 Malignant neoplasm of lower-outer quadrant of unspecified female breast
  • C50.521 Malignant neoplasm of lower-outer quadrant of right male breast
  • C50.522 Malignant neoplasm of lower-outer quadrant of left male breast
  • C50.529 Malignant neoplasm of lower-outer quadrant of unspecified male breast
  • C50.611 Malignant neoplasm of axillary tail of right female breast
  • C50.612 Malignant neoplasm of axillary tail of left female breast
  • C50.619 Malignant neoplasm of axillary tail of unspecified female breast
  • C50.621 Malignant neoplasm of axillary tail of right male breast
  • C50.622 Malignant neoplasm of axillary tail of left male breast
  • C50.629 Malignant neoplasm of axillary tail of unspecified male breast
  • C50.811 Malignant neoplasm of overlapping sites of right female breast
  • C50.812 Malignant neoplasm of overlapping sites of left female breast
  • C50.819 Malignant neoplasm of overlapping sites of unspecified female breast
  • C50.821 Malignant neoplasm of overlapping sites of right male breast
  • C50.822 Malignant neoplasm of overlapping sites of left male breast
  • C50.829 Malignant neoplasm of overlapping sites of unspecified male breast
  • C50.911 Malignant neoplasm of unspecified site of right female breast
  • C50.912 Malignant neoplasm of unspecified site of left female breast
  • C50.919 Malignant neoplasm of unspecified site of unspecified female breast
  • C50.921 Malignant neoplasm of unspecified site of right male breast
  • C50.922 Malignant neoplasm of unspecified site of left male breast
  • C50.929 Malignant neoplasm of unspecified site of unspecified male breast
  • C50.A0 Malignant inflammatory neoplasm of unspecified breast
  • C50.A1 Malignant inflammatory neoplasm of right breast
  • C50.A2 Malignant inflammatory neoplasm of left breast
C79 Secondary malignant neoplasm of other and unspecified sites2 codes
  • C79.2 Secondary malignant neoplasm of skin
  • C79.81 Secondary malignant neoplasm of breast
D05 Carcinoma in situ of breast12 codes
  • D05.00 Lobular carcinoma in situ of unspecified breast
  • D05.01 Lobular carcinoma in situ of right breast
  • D05.02 Lobular carcinoma in situ of left breast
  • D05.10 Intraductal carcinoma in situ of unspecified breast
  • D05.11 Intraductal carcinoma in situ of right breast
  • D05.12 Intraductal carcinoma in situ of left breast
  • D05.80 Other specified type of carcinoma in situ of unspecified breast
  • D05.81 Other specified type of carcinoma in situ of right breast
  • D05.82 Other specified type of carcinoma in situ of left breast
  • D05.90 Unspecified type of carcinoma in situ of unspecified breast
  • D05.91 Unspecified type of carcinoma in situ of right breast
  • D05.92 Unspecified type of carcinoma in situ of left breast
D48 Neoplasm of uncertain behavior of other and unspecified sites3 codes
  • D48.60 Neoplasm of uncertain behavior of unspecified breast
  • D48.61 Neoplasm of uncertain behavior of right breast
  • D48.62 Neoplasm of uncertain behavior of left breast
ICD-10-CM

Severity Exclusions 2 codes

When a case groups to DRG 583, these secondary diagnoses do not count as a CC or MCC for the severity split.

View excluded secondary diagnoses2
  • C79.2 Secondary malignant neoplasm of skin
  • C79.81 Secondary malignant neoplasm of breast

Frequently Asked Questions

What is MS-DRG 583?

MS-DRG 583 (Mastectomy for Malignancy without CC/MCC) is a surgical DRG in MDC 09 (Diseases & Disorders of the Skin, Subcutaneous Tissue & Breast). Its FY 2026 relative weight is 1.7244 with a geometric mean length of stay of 1.7 days.

What is the difference between DRG 582, 583?

All 2 share the same base category; the severity of secondary diagnoses separates them: 582 (with CC/MCC), 583 (without CC/MCC). A major complication or comorbidity (MCC) places the case in the highest-weighted DRG of the family; a CC in the middle; neither in the lowest.

How many procedure codes group to DRG 583?

61 ICD-10-PCS operating-room procedure codes group to this DRG.

What is the relative weight of DRG 583?

The FY 2026 relative weight of this DRG is 1.7244, meaning reimbursement of roughly 1.72 times the average Medicare inpatient case. Multiply by a hospital's blended base rate for the approximate payment.

← PreviousDRG 582 – Mastectomy for Malignancy with CC/MCC
Source: CMS ICD-10 MS-DRG v43.0 Definitions Manual and the FY 2026 IPPS Final Rule (Table 5), effective October 1, 2025 through September 30, 2026. We publish the DRG assignments as CMS defines them and add the navigation, search, and code links.