X2R Replacement - Cardiovascular System ICD-10-PCS
The X2R code range contains 10 ICD-10-PCS codes for Replacement procedures on the cardiovascular system. 9 of the codes are billable and valid for inpatient claim submission in fiscal year 2027.
Root Operation Definition
Replacement: Putting in or on biological or synthetic material that physically takes the place and/or function of all or a portion of a body part.
Codes in the X2R Range 10 codes · 9 billable
- X2R New Technology, Cardiovascular System, ReplacementNon-billable header
- X2R50WA Replacement of Right Upper Extremity Artery using Bioengineered Human Acellular Vessel, Open Approach, New Technology Group 10
- X2R60WA Replacement of Left Upper Extremity Artery using Bioengineered Human Acellular Vessel, Open Approach, New Technology Group 10
- X2R70WA Replacement of Right Lower Extremity Artery using Bioengineered Human Acellular Vessel, Open Approach, New Technology Group 10
- X2R80WA Replacement of Left Lower Extremity Artery using Bioengineered Human Acellular Vessel, Open Approach, New Technology Group 10
- X2RF3LC Replacement of Aortic Valve using Zooplastic Tissue, with Integrated Native Leaflet Clipping Locators, Percutaneous Approach, New Technology Group 12 New
- X2RG3FC Replacement of Mitral Valve with Balloon-expandable Bioprosthetic Valve with Dock, Percutaneous Approach, New Technology Group 12 New
- X2RH0GC Replacement of Pulmonary Valve using Size-Adjustable Synthetic Substitute, Open Approach, New Technology Group 12 New
- X2RJ3RA Replacement of Tricuspid Valve with Multi-plane Flex Technology Bioprosthetic Valve, Percutaneous Approach, New Technology Group 10
- X2RX0N7 Replacement of Thoracic Aorta, Arch using Branched Synthetic Substitute with Intraluminal Device, Open Approach, New Technology Group 7
About the X2R Code Range
These procedures place biological or synthetic material in or on an artery, heart valve, or aortic arch to take over all or part of it.
The fourth character identifies an upper or lower extremity artery and its side, a specific heart valve, or the aortic arch. The fifth distinguishes open access from access through a puncture or minor incision. The sixth identifies the replacement material or technology, including named replacement valves, synthetic substitutes, tissue with leaflet locators, and a bioengineered human vessel. The seventh identifies New Technology Group 7, 10, or 12.
FY 2027 changes: The FY 2027 ICD-10-PCS update, effective October 1, 2026, added X2RF3LC, X2RG3FC and X2RH0GC.
Questions About This Page
How many billable codes are in the X2R range?
Of the 10 codes in this range, 9 are billable and valid for inpatient claim submission from October 1, 2026 through September 30, 2027. Table header codes group them but cannot be reported on claims.
What does the X2R range classify?
The range classifies Replacement procedures, putting in or on biological or synthetic material that physically takes the place and/or function of all or a portion of a body part, performed on the cardiovascular system. Each code adds the body part, approach, device, and qualifier in characters four through seven, and links to its own reference page.
Related References
Source: CMS FY 2027 ICD-10-PCS order file and code tables, effective October 1, 2026 through September 30, 2027.
