ICD-10-PCS Tabular Index · Section X · FY 2026 X2R

X2R Replacement - Cardiovascular System ICD-10-PCS

The X2R code range contains 7 ICD-10-PCS codes for Replacement procedures on the cardiovascular system. 6 of the codes are billable and valid for inpatient claim submission in fiscal year 2026.

✓ Built from the official CMS FY 2026 datasetEffective Oct 1, 2025 – Sep 30, 2026
7
Procedure Codes
6
Billable Codes
X2R
Characters 1–3
X2
Parent Body System

Root Operation Definition

Replacement: Putting in or on biological or synthetic material that physically takes the place and/or function of all or a portion of a body part.

ICD-10-PCS

Codes in the X2R Range 7 codes · 6 billable

7 of 7 shown
  • X2R New Technology, Cardiovascular System, ReplacementNon-billable header
  • X2R50WA Replacement of Right Upper Extremity Artery using Bioengineered Human Acellular Vessel, Open Approach, New Technology Group 10 New
  • X2R60WA Replacement of Left Upper Extremity Artery using Bioengineered Human Acellular Vessel, Open Approach, New Technology Group 10 New
  • X2R70WA Replacement of Right Lower Extremity Artery using Bioengineered Human Acellular Vessel, Open Approach, New Technology Group 10 New
  • X2R80WA Replacement of Left Lower Extremity Artery using Bioengineered Human Acellular Vessel, Open Approach, New Technology Group 10 New
  • X2RJ3RA Replacement of Tricuspid Valve with Multi-plane Flex Technology Bioprosthetic Valve, Percutaneous Approach, New Technology Group 10 New
  • X2RX0N7 Replacement of Thoracic Aorta, Arch using Branched Synthetic Substitute with Intraluminal Device, Open Approach, New Technology Group 7

About the X2R Code Range

The ICD-10-PCS root operation Replacement (code X2R) in the New Technology section refers to the removal and substitution of a body part with a synthetic, bioengineered, or other new technology device. This operation is designed to restore the function of a body part using innovative materials or techniques.

Within this classification, the cardiovascular system is frequently targeted for replacement procedures. For example, codes such as X2R50WA and X2R60WA represent the replacement of the right and left upper extremity arteries using bioengineered human acellular vessels through an open approach. Similarly, X2R70WA and X2R80WA apply to the replacement of the right and left lower extremity arteries with the same type of vessel. Other examples include X2RJ3RA, indicating a percutaneous replacement of the tricuspid valve with a multi-plane flex bioprosthetic valve, highlighting minimally invasive techniques. Additionally, X2RX0N7 covers the open replacement of the thoracic aorta arch using a branched synthetic substitute with an intraluminal device. These specific replacement codes ensure precise documentation of new technology procedures in advanced cardiovascular care.

The ICD-10-PCS root operation Replacement (X2R) in the New Technology section involves removing a body part and substituting it with a new, often advanced, device or tissue. This procedure is commonly applied within the cardiovascular system to restore function by using innovative materials or techniques.

Examples of this operation include replacing various arteries such as the Right Upper Extremity Artery (X2R50WA) or Left Lower Extremity Artery (X2R80WA) using a Bioengineered Human Acellular Vessel through an Open Approach. Additionally, the Tricuspid Valve may be replaced with a Multi-plane Flex Technology Bioprosthetic Valve via a Percutaneous Approach (X2RJ3RA). Another example includes replacement of the Thoracic Aorta, Arch using a Branched Synthetic Substitute with Intraluminal Device (X2RX0N7). These codes highlight how new technology enhances replacement procedures by integrating advanced synthetic or bioengineered materials to restore vascular and cardiac function effectively.

Questions About This Page

How many billable codes are in the X2R range?

Of the 7 codes in this range, 6 are billable and valid for inpatient claim submission from October 1, 2025 through September 30, 2026. Table header codes group them but cannot be reported on claims.

What does the X2R range classify?

The range classifies Replacement procedures, putting in or on biological or synthetic material that physically takes the place and/or function of all or a portion of a body part, performed on the cardiovascular system. Each code adds the body part, approach, device, and qualifier in characters four through seven, and links to its own reference page.

Related References

Source: CMS FY 2026 ICD-10-PCS order file and code tables, effective October 1, 2025 through September 30, 2026.