005 Destruction - Central Nervous System and Cranial Nerves ICD-10-PCS
The 005 code range contains 95 ICD-10-PCS codes for Destruction procedures on the central nervous system and cranial nerves. 94 of the codes are billable and valid for inpatient claim submission in fiscal year 2026.
Root Operation Definition
Destruction: Physical eradication of all or a portion of a body part by the direct use of energy, force or a destructive agent.
Codes in the 005 Range 95 codes · 94 billable
- 005 Central Nervous System and Cranial Nerves, DestructionNon-billable header
- 00500Z3 Destruction of Brain using Laser Interstitial Thermal Therapy, Open Approach
- 00500ZZ Destruction of Brain, Open Approach
- 00503Z3 Destruction of Brain using Laser Interstitial Thermal Therapy, Percutaneous Approach
- 00503Z4 Destruction of Brain using Stereoelectroencephalographic Radiofrequency Ablation, Percutaneous Approach New
- 00503ZZ Destruction of Brain, Percutaneous Approach
- 00504Z3 Destruction of Brain using Laser Interstitial Thermal Therapy, Percutaneous Endoscopic Approach
- 00504ZZ Destruction of Brain, Percutaneous Endoscopic Approach
- 00510ZZ Destruction of Cerebral Meninges, Open Approach
- 00513ZZ Destruction of Cerebral Meninges, Percutaneous Approach
- 00514ZZ Destruction of Cerebral Meninges, Percutaneous Endoscopic Approach
- 00520ZZ Destruction of Dura Mater, Open Approach
- 00523ZZ Destruction of Dura Mater, Percutaneous Approach
- 00524ZZ Destruction of Dura Mater, Percutaneous Endoscopic Approach
- 00560ZZ Destruction of Cerebral Ventricle, Open Approach
- 00563ZZ Destruction of Cerebral Ventricle, Percutaneous Approach
- 00564ZZ Destruction of Cerebral Ventricle, Percutaneous Endoscopic Approach
- 00570ZZ Destruction of Cerebral Hemisphere, Open Approach
- 00573ZZ Destruction of Cerebral Hemisphere, Percutaneous Approach
- 00574ZZ Destruction of Cerebral Hemisphere, Percutaneous Endoscopic Approach
- 00580ZZ Destruction of Basal Ganglia, Open Approach
- 00583ZZ Destruction of Basal Ganglia, Percutaneous Approach
- 00584ZZ Destruction of Basal Ganglia, Percutaneous Endoscopic Approach
- 00590ZZ Destruction of Thalamus, Open Approach
- 00593ZZ Destruction of Thalamus, Percutaneous Approach
- 00594ZZ Destruction of Thalamus, Percutaneous Endoscopic Approach
- 005A0ZZ Destruction of Hypothalamus, Open Approach
- 005A3ZZ Destruction of Hypothalamus, Percutaneous Approach
- 005A4ZZ Destruction of Hypothalamus, Percutaneous Endoscopic Approach
- 005B0ZZ Destruction of Pons, Open Approach
- 005B3ZZ Destruction of Pons, Percutaneous Approach
- 005B4ZZ Destruction of Pons, Percutaneous Endoscopic Approach
- 005C0ZZ Destruction of Cerebellum, Open Approach
- 005C3ZZ Destruction of Cerebellum, Percutaneous Approach
- 005C4ZZ Destruction of Cerebellum, Percutaneous Endoscopic Approach
- 005D0ZZ Destruction of Medulla Oblongata, Open Approach
- 005D3ZZ Destruction of Medulla Oblongata, Percutaneous Approach
- 005D4ZZ Destruction of Medulla Oblongata, Percutaneous Endoscopic Approach
- 005F0ZZ Destruction of Olfactory Nerve, Open Approach
- 005F3ZZ Destruction of Olfactory Nerve, Percutaneous Approach
- 005F4ZZ Destruction of Olfactory Nerve, Percutaneous Endoscopic Approach
- 005G0ZZ Destruction of Optic Nerve, Open Approach
- 005G3ZZ Destruction of Optic Nerve, Percutaneous Approach
- 005G4ZZ Destruction of Optic Nerve, Percutaneous Endoscopic Approach
- 005H0ZZ Destruction of Oculomotor Nerve, Open Approach
- 005H3ZZ Destruction of Oculomotor Nerve, Percutaneous Approach
- 005H4ZZ Destruction of Oculomotor Nerve, Percutaneous Endoscopic Approach
- 005J0ZZ Destruction of Trochlear Nerve, Open Approach
- 005J3ZZ Destruction of Trochlear Nerve, Percutaneous Approach
- 005J4ZZ Destruction of Trochlear Nerve, Percutaneous Endoscopic Approach
- 005K0ZZ Destruction of Trigeminal Nerve, Open Approach
- 005K3ZZ Destruction of Trigeminal Nerve, Percutaneous Approach
- 005K4ZZ Destruction of Trigeminal Nerve, Percutaneous Endoscopic Approach
- 005L0ZZ Destruction of Abducens Nerve, Open Approach
- 005L3ZZ Destruction of Abducens Nerve, Percutaneous Approach
- 005L4ZZ Destruction of Abducens Nerve, Percutaneous Endoscopic Approach
- 005M0ZZ Destruction of Facial Nerve, Open Approach
- 005M3ZZ Destruction of Facial Nerve, Percutaneous Approach
- 005M4ZZ Destruction of Facial Nerve, Percutaneous Endoscopic Approach
- 005N0ZZ Destruction of Acoustic Nerve, Open Approach
- 005N3ZZ Destruction of Acoustic Nerve, Percutaneous Approach
- 005N4ZZ Destruction of Acoustic Nerve, Percutaneous Endoscopic Approach
- 005P0ZZ Destruction of Glossopharyngeal Nerve, Open Approach
- 005P3ZZ Destruction of Glossopharyngeal Nerve, Percutaneous Approach
- 005P4ZZ Destruction of Glossopharyngeal Nerve, Percutaneous Endoscopic Approach
- 005Q0ZZ Destruction of Vagus Nerve, Open Approach
- 005Q3ZZ Destruction of Vagus Nerve, Percutaneous Approach
- 005Q4ZZ Destruction of Vagus Nerve, Percutaneous Endoscopic Approach
- 005R0ZZ Destruction of Accessory Nerve, Open Approach
- 005R3ZZ Destruction of Accessory Nerve, Percutaneous Approach
- 005R4ZZ Destruction of Accessory Nerve, Percutaneous Endoscopic Approach
- 005S0ZZ Destruction of Hypoglossal Nerve, Open Approach
- 005S3ZZ Destruction of Hypoglossal Nerve, Percutaneous Approach
- 005S4ZZ Destruction of Hypoglossal Nerve, Percutaneous Endoscopic Approach
- 005T0ZZ Destruction of Spinal Meninges, Open Approach
- 005T3ZZ Destruction of Spinal Meninges, Percutaneous Approach
- 005T4ZZ Destruction of Spinal Meninges, Percutaneous Endoscopic Approach
- 005W0Z3 Destruction of Cervical Spinal Cord using Laser Interstitial Thermal Therapy, Open Approach
- 005W0ZZ Destruction of Cervical Spinal Cord, Open Approach
- 005W3Z3 Destruction of Cervical Spinal Cord using Laser Interstitial Thermal Therapy, Percutaneous Approach
- 005W3ZZ Destruction of Cervical Spinal Cord, Percutaneous Approach
- 005W4Z3 Destruction of Cervical Spinal Cord using Laser Interstitial Thermal Therapy, Percutaneous Endoscopic Approach
- 005W4ZZ Destruction of Cervical Spinal Cord, Percutaneous Endoscopic Approach
- 005X0Z3 Destruction of Thoracic Spinal Cord using Laser Interstitial Thermal Therapy, Open Approach
- 005X0ZZ Destruction of Thoracic Spinal Cord, Open Approach
- 005X3Z3 Destruction of Thoracic Spinal Cord using Laser Interstitial Thermal Therapy, Percutaneous Approach
- 005X3ZZ Destruction of Thoracic Spinal Cord, Percutaneous Approach
- 005X4Z3 Destruction of Thoracic Spinal Cord using Laser Interstitial Thermal Therapy, Percutaneous Endoscopic Approach
- 005X4ZZ Destruction of Thoracic Spinal Cord, Percutaneous Endoscopic Approach
- 005Y0Z3 Destruction of Lumbar Spinal Cord using Laser Interstitial Thermal Therapy, Open Approach
- 005Y0ZZ Destruction of Lumbar Spinal Cord, Open Approach
- 005Y3Z3 Destruction of Lumbar Spinal Cord using Laser Interstitial Thermal Therapy, Percutaneous Approach
- 005Y3ZZ Destruction of Lumbar Spinal Cord, Percutaneous Approach
- 005Y4Z3 Destruction of Lumbar Spinal Cord using Laser Interstitial Thermal Therapy, Percutaneous Endoscopic Approach
- 005Y4ZZ Destruction of Lumbar Spinal Cord, Percutaneous Endoscopic Approach
About the 005 Code Range
The ICD-10-PCS root operation Destruction (code series 005) refers to the physical eradication of a body part or tissue. In the Medical and Surgical section, this operation targets the Central Nervous System and Cranial Nerves, aiming to destroy abnormal or problematic tissues.
This root operation includes various approaches such as Open, Percutaneous, and Percutaneous Endoscopic. For example, destruction of the Brain can be done using Laser Interstitial Thermal Therapy via an open approach (00500Z3) or a minimally invasive percutaneous approach (00503Z3). Other body parts documented include the Cerebral Meninges (00510ZZ), Dura Mater (00520ZZ), various cranial nerves like the Optic Nerve (005G0ZZ) and Facial Nerve (005M0ZZ), as well as spinal cord segments such as the Cervical Spinal Cord (005W0ZZ). This detailed classification allows precise coding of procedures that eliminate harmful nervous system tissue, reflecting both the target site and technique used.
Questions About This Page
How many billable codes are in the 005 range?
Of the 95 codes in this range, 94 are billable and valid for inpatient claim submission from October 1, 2025 through September 30, 2026. Table header codes group them but cannot be reported on claims.
What does the 005 range classify?
The range classifies Destruction procedures, physical eradication of all or a portion of a body part by the direct use of energy, force or a destructive agent, performed on the central nervous system and cranial nerves. Each code adds the body part, approach, device, and qualifier in characters four through seven, and links to its own reference page.
Related References
Source: CMS FY 2026 ICD-10-PCS order file and code tables, effective October 1, 2025 through September 30, 2026.
