00500Z3Destruction of Brain using Laser Interstitial Thermal Therapy, Open Approach
- Billable / Specific Code
00500Z3 is a billable ICD-10-PCS procedure code for Destruction of Brain using Laser Interstitial Thermal Therapy, Open Approach. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to 13 MS-DRGs. The root operation Destruction involves physical eradication of all or a portion of a body part by the direct use of energy, force, or a destructive agent. In AHRQ's Clinical Classifications Software (CCSR), this procedure falls under CNS excision procedures.
Code Identity
PCS Table Breakdown
Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.
| Position | Designation | Value | Meaning |
|---|---|---|---|
| 1 | Section | 0 | Medical and Surgical |
| 2 | Body System | 0 | Central Nervous System and Cranial Nerves |
| 3 | Operation | 5 | Destruction |
| 4 | BodyPart | 0 | Brain |
| 5 | Approach | 0 | Open |
| 6 | Device | Z | No Device |
| 7 | Qualifier | 3 | Laser Interstitial Thermal Therapy |
In the ICD-10-PCS Alphabetic Index
These FY 2027 ICD-10-PCS Alphabetic Index entries lead to this code:
To code destruction of the brain, open the FY 2027 ICD-10-PCS Alphabetic Index at Destruction, then the subterm Brain. The index leads to table 005, where the approach, device and qualifier values shown in the breakdown above complete the seven-character code 00500Z3.
Clinical Classification (CCSR)
AHRQ groups this procedure code into these clinical categories.
Code History
Similar Procedure Codes
Questions About 00500Z3
Is 00500Z3 a billable code?
Yes. This is a complete seven-character ICD-10-PCS code, specific enough to report Destruction of Brain using Laser Interstitial Thermal Therapy, Open Approach on inpatient claims from October 1, 2026 through September 30, 2027.
What do the characters in 00500Z3 mean?
The code breaks down character by character: the 1st character 0 is the Section (Medical and Surgical); the 2nd character 0 is the Body System (Central Nervous System and Cranial Nerves); the 3rd character 5 is the Operation (Destruction); the 4th character 0 is the BodyPart (Brain); the 5th character 0 is the Approach (Open); the 6th character Z is the Device (No Device); the 7th character 3 is the Qualifier (Laser Interstitial Thermal Therapy).
What MS-DRG does 00500Z3 group to?
On an inpatient stay, Destruction of Brain using Laser Interstitial Thermal Therapy, Open Approach maps to MS-DRGs 025, 026, 027, 820, 821, 822, 826, 827, 828, 907, 908, 909, 955, with relative weights from 1.1267 to 6.5257. The MS-DRG sets the fixed Medicare payment for the stay.
