3E0S33ZIntroduction of Anti-inflammatory into Epidural Space, Percutaneous Approach

Administration›Physiological Systems and Anatomical Regions›Introduction

Billable / Specific Code

ICD-10-PCS 3E0S33Z

CMS Source: FY 2026 ICD-10-PCS dataset. Effective Oct 1, 2025 – Sep 30, 2026.

3E0S33Z is a billable ICD-10-PCS procedure code for Introduction of Anti-inflammatory into Epidural Space, Percutaneous Approach. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

Code Identity

ICD-10-PCS Code

3E0S33Z

Billable Status

Yes — Valid for Submission

Code Describes

Introduction of Anti-inflammatory into Epidural Space, Percutaneous Approach

Parent Code

3E0

Short Description

Introduce of Anti-inflam into Epidural Space, Perc Approach

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

Position	Designation	Value	Meaning
1	Section	3	Administration
2	Body System	E	Physiological Systems and Anatomical Regions
3	Operation	0	Introduction
4	BodySystem/Region	S	Epidural Space
5	Approach	3	Percutaneous
6	Substance	3	Anti-inflammatory
7	Qualifier	Z	No Qualifier

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for 3E0S33Z under the General Equivalence Mappings.

39.2

Approximate match.

99.23

Approximate match; combination (more than one code may be needed).

Similar Procedure Codes

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Questions About 3E0S33Z

Is 3E0S33Z a billable code?

Yes. 3E0S33Z is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of Anti-inflammatory into Epidural Space, Percutaneous Approach on inpatient claims from October 1, 2025 through September 30, 2026.

What do the characters in 3E0S33Z mean?

3E0S33Z breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character S is the BodySystem/Region (Epidural Space); the 5th character 3 is the Approach (Percutaneous); the 6th character 3 is the Substance (Anti-inflammatory); the 7th character Z is the Qualifier (No Qualifier).

What is the ICD-9-PCS equivalent of 3E0S33Z?

Under the General Equivalence Mappings, Introduction of Anti-inflammatory into Epidural Space, Percutaneous Approach crosswalks to ICD-9-PCS 39.2, 39.2, and 99.23. The mapping is approximate, so confirm it fits the documentation.