3E0Q0E0Introduction of Autologous Somatic Stem Cells into Cranial Cavity and Brain, Open Approach

Administration›Physiological Systems and Anatomical Regions›Introduction
  • Billable / Specific Code
ICD-10-PCS 3E0Q0E0
CMS Source: FY 2027 ICD-10-PCS dataset. Effective Oct 1, 2026 – Sep 30, 2027.FacebookXLinkedInPrint

3E0Q0E0 is a billable ICD-10-PCS procedure code for Introduction of Autologous Somatic Stem Cells into Cranial Cavity and Brain, Open Approach. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027). The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products. In AHRQ's Clinical Classifications Software (CCSR), this procedure falls under Administration and transfusion of bone marrow, stem cells, pancreatic islet cells, and t-cells.

Code Identity

ICD-10-PCS Code
3E0Q0E0
Billable Status
Yes — Valid for Submission
Code Describes
Introduction of Autologous Somatic Stem Cells into Cranial Cavity and Brain, Open Approach
Short Description
Introduce Autol Somat Stem Cell in Cran Cav/Brain, Open
Parent Code
3E0

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

PositionDesignationValueMeaning
1Section3Administration
2Body SystemEPhysiological Systems and Anatomical Regions
3Operation0Introduction
4BodySystem/RegionQCranial Cavity and Brain
5Approach0Open
6SubstanceEStem Cells, Somatic
7Qualifier0Autologous

In the ICD-10-PCS Alphabetic Index

These FY 2027 ICD-10-PCS Alphabetic Index entries lead to this code:

Introduction of substance in or on, Brain
Leads to this code's table
Introduction of substance in or on, Brain, Gas
Leads to this code's table
Introduction of substance in or on, Cranial Cavity
Leads to this code's table
Introduction of substance in or on, Brain, Hypnotics
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Introduction of substance in or on, Brain, Sedatives
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Introduction of substance in or on, Brain, Analgesics
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Introduction of substance in or on, Cranial Cavity, Gas
Leads to this code's table
Introduction of substance in or on, Brain, Anti-infective
Leads to this code's table
Introduction of substance in or on, Brain, Antineoplastic
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Introduction of substance in or on, Brain, Anesthetic Agent
Leads to this code's table
Introduction of substance in or on, Brain, Anti-inflammatory
Leads to this code's table
Introduction of substance in or on, Brain, Destructive Agent
Leads to this code's table
Introduction of substance in or on, Brain, Stem Cells, Somatic
Leads to this code's table
Introduction of substance in or on, Cranial Cavity, Hypnotics
Leads to this code's table
Introduction of substance in or on, Cranial Cavity, Sedatives
Leads to this code's table

Browse the full ICD-10-PCS Alphabetic Index →

Clinical Classification (CCSR)

AHRQ groups this procedure code into these clinical categories.

ADM011
Administration and transfusion of bone marrow, stem cells, pancreatic islet cells, and t-cells
Clinical domain: Administration of Therapeutic Substances

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for this code under the General Equivalence Mappings.

01.09
Other cranial puncture
Approximate match.

Similar Procedure Codes

Questions About 3E0Q0E0

Is 3E0Q0E0 a billable code?

Yes. This is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of Autologous Somatic Stem Cells into Cranial Cavity and Brain, Open Approach on inpatient claims from October 1, 2026 through September 30, 2027.

What do the characters in 3E0Q0E0 mean?

The code breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character Q is the BodySystem/Region (Cranial Cavity and Brain); the 5th character 0 is the Approach (Open); the 6th character E is the Substance (Stem Cells, Somatic); the 7th character 0 is the Qualifier (Autologous).

What is the ICD-9-PCS equivalent of 3E0Q0E0?

Under the General Equivalence Mappings, Introduction of Autologous Somatic Stem Cells into Cranial Cavity and Brain, Open Approach crosswalks to ICD-9-PCS 01.09 (Other cranial puncture). The mapping is approximate, so confirm it fits the documentation.