3E0Q00MIntroduction of Antineoplastic, Monoclonal Antibody, into Cranial Cavity and Brain, Open Approach

Administration›Physiological Systems and Anatomical Regions›Introduction
  • Billable / Specific Code
ICD-10-PCS 3E0Q00M
CMS Source: FY 2026 ICD-10-PCS dataset. Effective Oct 1, 2025 – Sep 30, 2026.FacebookXLinkedInPrint

3E0Q00M is a billable ICD-10-PCS procedure code for Introduction of Antineoplastic, Monoclonal Antibody, into Cranial Cavity and Brain, Open Approach. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

Code Identity

ICD-10-PCS Code
3E0Q00M
Billable Status
Yes — Valid for Submission
Code Describes
Introduction of Antineoplastic, Monoclonal Antibody, into Cranial Cavity and Brain, Open Approach
Parent Code
3E0
Short Description
Introduce Antneo, Moncln Ab, in Cran Cav/Brain, Open

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

PositionDesignationValueMeaning
1Section3Administration
2Body SystemEPhysiological Systems and Anatomical Regions
3Operation0Introduction
4BodySystem/RegionQCranial Cavity and Brain
5Approach0Open
6Substance0Antineoplastic
7QualifierMMonoclonal Antibody

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for 3E0Q00M under the General Equivalence Mappings.

99.28
Approximate match.

Code History

Replaces previously assigned code(s):
  • 3E0Q30M — Introduce Monoclonal Antibody in Cran Cav/Brain, Perc

Similar Procedure Codes

Questions About 3E0Q00M

Is 3E0Q00M a billable code?

Yes. 3E0Q00M is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of Antineoplastic, Monoclonal Antibody, into Cranial Cavity and Brain, Open Approach on inpatient claims from October 1, 2025 through September 30, 2026.

What do the characters in 3E0Q00M mean?

3E0Q00M breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character Q is the BodySystem/Region (Cranial Cavity and Brain); the 5th character 0 is the Approach (Open); the 6th character 0 is the Substance (Antineoplastic); the 7th character M is the Qualifier (Monoclonal Antibody).

What is the ICD-9-PCS equivalent of 3E0Q00M?

Under the General Equivalence Mappings, Introduction of Antineoplastic, Monoclonal Antibody, into Cranial Cavity and Brain, Open Approach crosswalks to ICD-9-PCS 99.28. The mapping is approximate, so confirm it fits the documentation.