3E03305Introduction of Other Antineoplastic into Peripheral Vein, Percutaneous Approach

  • Billable / Specific Code
ICD-10-PCS 3E03305
CMS Source: FY 2027 ICD-10-PCS dataset. Effective Oct 1, 2026 – Sep 30, 2027.FacebookXLinkedInPrint

3E03305 is a billable ICD-10-PCS procedure code for Introduction of Other Antineoplastic into Peripheral Vein, Percutaneous Approach. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027). The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products. In AHRQ's Clinical Classifications Software (CCSR), this procedure falls under Chemotherapy.

Code Identity

ICD-10-PCS Code
3E03305
Billable Status
Yes — Valid for Submission
Code Describes
Introduction of Other Antineoplastic into Peripheral Vein, Percutaneous Approach
Short Description
Introduce Oth Antineoplastic in Periph Vein, Perc
Parent Code

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

PositionDesignationValueMeaning
1Section3Administration
2Body SystemEPhysiological Systems and Anatomical Regions
3Operation0Introduction
4BodySystem/Region3Peripheral Vein
5Approach3Percutaneous
6Substance0Antineoplastic
7Qualifier5Other Antineoplastic

In the ICD-10-PCS Alphabetic Index

These FY 2027 ICD-10-PCS Alphabetic Index entries lead to this code:

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Browse the full ICD-10-PCS Alphabetic Index →

Clinical Classification (CCSR)

AHRQ groups this procedure code into these clinical categories.

ADM012
Chemotherapy
Clinical domain: Administration of Therapeutic Substances

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for this code under the General Equivalence Mappings.

39.97
Other perfusion
Approximate match.
99.25
Injection or infusion of cancer chemotherapeutic substance
Approximate match.

Code History

Replaces previously assigned code(s):
  • XW03351 — Introduce Blinatumomab in Periph Vein, Perc, New Tech 1
  • XW03387 — Introduce Lurbinectedin in Periph Vein, Perc, New Tech 7
  • XW033D6 — Introduce Atezolizumab in Periph Vein, Perc, New Tech 6
Replaced in the FY 2027 code set by:
  • XW03358 — Introduce Mosunetuzumab in Periph Vein, Perc, New Tech 8
  • XW03368 — Introduce Afamitresgene in Periph Vein, Perc, New Tech 8
  • XW03378 — Introduce Tabelecleucel in Periph Vein, Perc, New Tech 8
  • XW03387 — Introduce Lurbinectedin in Periph Vein, Perc, New Tech 7
  • XW0339A — Introduce Odronextamab in Periph Vein, Perc, New Tech 10
  • XW033B3 — Introduce cytarab/daunorub in Periph Vein, Perc, New Tech 3
  • XW033C3 — Introduce Auto CAR T cell in Periph Vein, Perc, New Tech 3
  • XW033CA — Introduce Zanidatamab in Periph Vein, Perc, New Tech 10
  • XW033D6 — Introduce Atezolizumab in Periph Vein, Perc, New Tech 6
  • XW033NA — Introduce Tarlatamab-dlle in Periph Vein, Perc, New Tech 10
  • XW033P9 — Introduce Glofitamab in Periph Vein, Perc, New Tech 9
  • XW033Q5 — Introduce Tagraxofusp-erzs in Periph Vein, Perc, New Tech 5
  • XW033S5 — Introduce Iobenguane I-131 in Periph Vein, Perc, New Tech 5
  • XW23346 — Transfuse Brexcab Autoleuc in Periph Vein, Perc, New Tech 6
  • XW23376 — Transfuse Lisocab Maraleuc in Periph Vein, Perc, New Tech 6

Similar Procedure Codes

Questions About 3E03305

Is 3E03305 a billable code?

Yes. This is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of Other Antineoplastic into Peripheral Vein, Percutaneous Approach on inpatient claims from October 1, 2026 through September 30, 2027.

What do the characters in 3E03305 mean?

The code breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character 3 is the BodySystem/Region (Peripheral Vein); the 5th character 3 is the Approach (Percutaneous); the 6th character 0 is the Substance (Antineoplastic); the 7th character 5 is the Qualifier (Other Antineoplastic).

What is the ICD-9-PCS equivalent of 3E03305?

Under the General Equivalence Mappings, Introduction of Other Antineoplastic into Peripheral Vein, Percutaneous Approach crosswalks to ICD-9-PCS 39.97 (Other perfusion) and 99.25 (Injection or infusion of cancer chemotherapeutic substance). The mapping is approximate, so confirm it fits the documentation.