3E03003Introduction of Low-dose Interleukin-2 into Peripheral Vein, Open Approach

Administration›Physiological Systems and Anatomical Regions›Introduction
  • Billable / Specific Code
ICD-10-PCS 3E03003
CMS Source: FY 2026 ICD-10-PCS dataset. Effective Oct 1, 2025 – Sep 30, 2026.FacebookXLinkedInPrint

3E03003 is a billable ICD-10-PCS procedure code for Introduction of Low-dose Interleukin-2 into Peripheral Vein, Open Approach. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

Code Identity

ICD-10-PCS Code
3E03003
Billable Status
Yes — Valid for Submission
Code Describes
Introduction of Low-dose Interleukin-2 into Peripheral Vein, Open Approach
Parent Code
3E0
Short Description
Introduce of Low dose IL-2 into Periph Vein, Open Approach

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

PositionDesignationValueMeaning
1Section3Administration
2Body SystemEPhysiological Systems and Anatomical Regions
3Operation0Introduction
4BodySystem/Region3Peripheral Vein
5Approach0Open
6Substance0Antineoplastic
7Qualifier3Low-dose Interleukin-2

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for 3E03003 under the General Equivalence Mappings.

99.28
Approximate match.

Similar Procedure Codes

Questions About 3E03003

Is 3E03003 a billable code?

Yes. 3E03003 is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of Low-dose Interleukin-2 into Peripheral Vein, Open Approach on inpatient claims from October 1, 2025 through September 30, 2026.

What do the characters in 3E03003 mean?

3E03003 breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character 3 is the BodySystem/Region (Peripheral Vein); the 5th character 0 is the Approach (Open); the 6th character 0 is the Substance (Antineoplastic); the 7th character 3 is the Qualifier (Low-dose Interleukin-2).

What is the ICD-9-PCS equivalent of 3E03003?

Under the General Equivalence Mappings, Introduction of Low-dose Interleukin-2 into Peripheral Vein, Open Approach crosswalks to ICD-9-PCS 99.28. The mapping is approximate, so confirm it fits the documentation.