3E0134ZIntroduction of Serum, Toxoid and Vaccine into Subcutaneous Tissue, Percutaneous Approach

Administration›Physiological Systems and Anatomical Regions›Introduction

Billable / Specific Code

ICD-10-PCS 3E0134Z

CMS Source: FY 2026 ICD-10-PCS dataset. Effective Oct 1, 2025 – Sep 30, 2026.

3E0134Z is a billable ICD-10-PCS procedure code for Introduction of Serum, Toxoid and Vaccine into Subcutaneous Tissue, Percutaneous Approach. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

Code Identity

ICD-10-PCS Code

3E0134Z

Billable Status

Yes — Valid for Submission

Code Describes

Introduction of Serum, Toxoid and Vaccine into Subcutaneous Tissue, Percutaneous Approach

Parent Code

3E0

Short Description

Introduction of Serum/Tox/Vaccine into Subcu, Perc Approach

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

Position	Designation	Value	Meaning
1	Section	3	Administration
2	Body System	E	Physiological Systems and Anatomical Regions
3	Operation	0	Introduction
4	BodySystem/Region	1	Subcutaneous Tissue
5	Approach	3	Percutaneous
6	Substance	4	Serum, Toxoid and Vaccine
7	Qualifier	Z	No Qualifier

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for 3E0134Z under the General Equivalence Mappings.

99.59

Approximate match.

Code History

Replaced in the FY 2026 code set by:

3E01340 — Introduction of Influenza Vaccine into Subcu, Perc Approach
XW013S6 — Introduce COVID19 Vacc Ds1 in Subcu, Perc, New Tech 6
XW013T6 — Introduce COVID19 Vacc Ds2 in Subcu, Perc, New Tech 6
XW013U6 — Introduce COVID19 Vacc in Subcu, Perc, New Tech 6

Similar Procedure Codes

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Questions About 3E0134Z

Is 3E0134Z a billable code?

Yes. 3E0134Z is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of Serum, Toxoid and Vaccine into Subcutaneous Tissue, Percutaneous Approach on inpatient claims from October 1, 2025 through September 30, 2026.

What do the characters in 3E0134Z mean?

3E0134Z breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character 1 is the BodySystem/Region (Subcutaneous Tissue); the 5th character 3 is the Approach (Percutaneous); the 6th character 4 is the Substance (Serum, Toxoid and Vaccine); the 7th character Z is the Qualifier (No Qualifier).

What is the ICD-9-PCS equivalent of 3E0134Z?

Under the General Equivalence Mappings, Introduction of Serum, Toxoid and Vaccine into Subcutaneous Tissue, Percutaneous Approach crosswalks to ICD-9-PCS 99.59. The mapping is approximate, so confirm it fits the documentation.