0F500ZFDestruction of Liver using Irreversible Electroporation, Open Approach

  • Billable / Specific Code
ICD-10-PCS 0F500ZF
CMS Source: FY 2027 ICD-10-PCS dataset. Effective Oct 1, 2026 – Sep 30, 2027.FacebookXLinkedInPrint

0F500ZF is a billable ICD-10-PCS procedure code for Destruction of Liver using Irreversible Electroporation, Open Approach. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to 6 MS-DRGs. The root operation Destruction involves physical eradication of all or a portion of a body part by the direct use of energy, force, or a destructive agent. In AHRQ's Clinical Classifications Software (CCSR), this procedure falls under Hepatobiliary resection and ablation.

Code Identity

ICD-10-PCS Code
0F500ZF
Billable Status
Yes — Valid for Submission
Code Describes
Destruction of Liver using Irreversible Electroporation, Open Approach
Short Description
Destruction of Liver using IRE, Open Approach
Parent Code

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

PositionDesignationValueMeaning
1Section0Medical and Surgical
2Body SystemFHepatobiliary System and Pancreas
3Operation5Destruction
4BodyPart0Liver
5Approach0Open
6DeviceZNo Device
7QualifierFIrreversible Electroporation

In the ICD-10-PCS Alphabetic Index

These FY 2027 ICD-10-PCS Alphabetic Index entries lead to this code:

Anatomy or device term that leads here
Leads to this code's table
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To code destruction of the liver, open the FY 2027 ICD-10-PCS Alphabetic Index at Destruction, then the subterm Liver. The index leads to table 0F5, where the approach, device and qualifier values shown in the breakdown above complete the seven-character code 0F500ZF.

Browse the full ICD-10-PCS Alphabetic Index →

Clinical Classification (CCSR)

AHRQ groups this procedure code into these clinical categories.

HEP004
Hepatobiliary resection and ablation
Clinical domain: Hepatobiliary and Pancreas Procedures

Code History

Replaces previously assigned code(s):
  • 0F500ZZ — Destruction of Liver, Open Approach

Similar Procedure Codes

Questions About 0F500ZF

Is 0F500ZF a billable code?

Yes. This is a complete seven-character ICD-10-PCS code, specific enough to report Destruction of Liver using Irreversible Electroporation, Open Approach on inpatient claims from October 1, 2026 through September 30, 2027.

What do the characters in 0F500ZF mean?

The code breaks down character by character: the 1st character 0 is the Section (Medical and Surgical); the 2nd character F is the Body System (Hepatobiliary System and Pancreas); the 3rd character 5 is the Operation (Destruction); the 4th character 0 is the BodyPart (Liver); the 5th character 0 is the Approach (Open); the 6th character Z is the Device (No Device); the 7th character F is the Qualifier (Irreversible Electroporation).

What MS-DRG does 0F500ZF group to?

On an inpatient stay, Destruction of Liver using Irreversible Electroporation, Open Approach maps to MS-DRGs 356, 357, 358, 405, 406, 407, with relative weights from 1.4884 to 5.3816. The MS-DRG sets the fixed Medicare payment for the stay.