MS-DRG · FY 2026 v43.0

MS-DRG 61 – Ischemic Stroke, Precerebral Occlusion or Transient Ischemia with Thrombolytic Agent with MCC

A Medical DRG in MDC 01 (Diseases & Disorders of the Nervous System). Inpatient cases group to DRG 61 when the ICD-10-CM principal diagnosis is one of the 130 codes listed below and a secondary diagnosis on the major complication or comorbidity (MCC) list is present. Its FY 2026 relative weight is 2.7571 with a geometric mean length of stay of 4.7 days.

Medical DRG – assigned by principal diagnosis✓ Official CMS v43.0 dataset
2.7571
Relative Weight
4.7
Geometric Mean LOS (days)
6.2
Arithmetic Mean LOS (days)
130
Principal Diagnosis Codes
10
Procedure Codes

Severity family

DRG 61with MCCWeight 2.7571 · GMLOS 4.7 daysDRG 62with CCWeight 1.7572 · GMLOS 3.0 daysDRG 63without CC/MCCWeight 1.4038 · GMLOS 2.2 days
How a case is assigned to DRG 61

The grouper first assigns the case to MDC 01 from the principal diagnosis and finds no qualifying operating-room procedure (this is a Medical DRG; ICD-10-PCS codes do not drive assignment here), then applies the severity split from secondary diagnoses: with MCC → 61; with CC → 62; without CC/MCC → 63.

ICD-10-CM

Principal Diagnosis Codes 130 codes · 6 categories

130 of 130 shown
G45 Transient cerebral ischemic attacks and related syndromes5 codes
  • G45.0 Vertebro-basilar artery syndrome
  • G45.1 Carotid artery syndrome (hemispheric)
  • G45.2 Multiple and bilateral precerebral artery syndromes
  • G45.8 Other transient cerebral ischemic attacks and related syndromes
  • G45.9 Transient cerebral ischemic attack, unspecified
G46 Vascular syndromes of brain in cerebrovascular diseases3 codes
  • G46.0 Middle cerebral artery syndrome
  • G46.1 Anterior cerebral artery syndrome
  • G46.2 Posterior cerebral artery syndrome
I63 Cerebral infarction91 codes
  • I63.00 Cerebral infarction due to thrombosis of unspecified precerebral artery
  • I63.011 Cerebral infarction due to thrombosis of right vertebral artery
  • I63.012 Cerebral infarction due to thrombosis of left vertebral artery
  • I63.013 Cerebral infarction due to thrombosis of bilateral vertebral arteries
  • I63.019 Cerebral infarction due to thrombosis of unspecified vertebral artery
  • I63.02 Cerebral infarction due to thrombosis of basilar artery
  • I63.031 Cerebral infarction due to thrombosis of right carotid artery
  • I63.032 Cerebral infarction due to thrombosis of left carotid artery
  • I63.033 Cerebral infarction due to thrombosis of bilateral carotid arteries
  • I63.039 Cerebral infarction due to thrombosis of unspecified carotid artery
  • I63.09 Cerebral infarction due to thrombosis of other precerebral artery
  • I63.10 Cerebral infarction due to embolism of unspecified precerebral artery
  • I63.111 Cerebral infarction due to embolism of right vertebral artery
  • I63.112 Cerebral infarction due to embolism of left vertebral artery
  • I63.113 Cerebral infarction due to embolism of bilateral vertebral arteries
  • I63.119 Cerebral infarction due to embolism of unspecified vertebral artery
  • I63.12 Cerebral infarction due to embolism of basilar artery
  • I63.131 Cerebral infarction due to embolism of right carotid artery
  • I63.132 Cerebral infarction due to embolism of left carotid artery
  • I63.133 Cerebral infarction due to embolism of bilateral carotid arteries
  • I63.139 Cerebral infarction due to embolism of unspecified carotid artery
  • I63.19 Cerebral infarction due to embolism of other precerebral artery
  • I63.20 Cerebral infarction due to unspecified occlusion or stenosis of unspecified precerebral arteries
  • I63.211 Cerebral infarction due to unspecified occlusion or stenosis of right vertebral artery
  • I63.212 Cerebral infarction due to unspecified occlusion or stenosis of left vertebral artery
  • I63.213 Cerebral infarction due to unspecified occlusion or stenosis of bilateral vertebral arteries
  • I63.219 Cerebral infarction due to unspecified occlusion or stenosis of unspecified vertebral artery
  • I63.22 Cerebral infarction due to unspecified occlusion or stenosis of basilar artery
  • I63.231 Cerebral infarction due to unspecified occlusion or stenosis of right carotid arteries
  • I63.232 Cerebral infarction due to unspecified occlusion or stenosis of left carotid arteries
  • I63.233 Cerebral infarction due to unspecified occlusion or stenosis of bilateral carotid arteries
  • I63.239 Cerebral infarction due to unspecified occlusion or stenosis of unspecified carotid artery
  • I63.29 Cerebral infarction due to unspecified occlusion or stenosis of other precerebral arteries
  • I63.30 Cerebral infarction due to thrombosis of unspecified cerebral artery
  • I63.311 Cerebral infarction due to thrombosis of right middle cerebral artery
  • I63.312 Cerebral infarction due to thrombosis of left middle cerebral artery
  • I63.313 Cerebral infarction due to thrombosis of bilateral middle cerebral arteries
  • I63.319 Cerebral infarction due to thrombosis of unspecified middle cerebral artery
  • I63.321 Cerebral infarction due to thrombosis of right anterior cerebral artery
  • I63.322 Cerebral infarction due to thrombosis of left anterior cerebral artery
  • I63.323 Cerebral infarction due to thrombosis of bilateral anterior cerebral arteries
  • I63.329 Cerebral infarction due to thrombosis of unspecified anterior cerebral artery
  • I63.331 Cerebral infarction due to thrombosis of right posterior cerebral artery
  • I63.332 Cerebral infarction due to thrombosis of left posterior cerebral artery
  • I63.333 Cerebral infarction due to thrombosis of bilateral posterior cerebral arteries
  • I63.339 Cerebral infarction due to thrombosis of unspecified posterior cerebral artery
  • I63.341 Cerebral infarction due to thrombosis of right cerebellar artery
  • I63.342 Cerebral infarction due to thrombosis of left cerebellar artery
  • I63.343 Cerebral infarction due to thrombosis of bilateral cerebellar arteries
  • I63.349 Cerebral infarction due to thrombosis of unspecified cerebellar artery
  • I63.39 Cerebral infarction due to thrombosis of other cerebral artery
  • I63.40 Cerebral infarction due to embolism of unspecified cerebral artery
  • I63.411 Cerebral infarction due to embolism of right middle cerebral artery
  • I63.412 Cerebral infarction due to embolism of left middle cerebral artery
  • I63.413 Cerebral infarction due to embolism of bilateral middle cerebral arteries
  • I63.419 Cerebral infarction due to embolism of unspecified middle cerebral artery
  • I63.421 Cerebral infarction due to embolism of right anterior cerebral artery
  • I63.422 Cerebral infarction due to embolism of left anterior cerebral artery
  • I63.423 Cerebral infarction due to embolism of bilateral anterior cerebral arteries
  • I63.429 Cerebral infarction due to embolism of unspecified anterior cerebral artery
  • I63.431 Cerebral infarction due to embolism of right posterior cerebral artery
  • I63.432 Cerebral infarction due to embolism of left posterior cerebral artery
  • I63.433 Cerebral infarction due to embolism of bilateral posterior cerebral arteries
  • I63.439 Cerebral infarction due to embolism of unspecified posterior cerebral artery
  • I63.441 Cerebral infarction due to embolism of right cerebellar artery
  • I63.442 Cerebral infarction due to embolism of left cerebellar artery
  • I63.443 Cerebral infarction due to embolism of bilateral cerebellar arteries
  • I63.449 Cerebral infarction due to embolism of unspecified cerebellar artery
  • I63.49 Cerebral infarction due to embolism of other cerebral artery
  • I63.50 Cerebral infarction due to unspecified occlusion or stenosis of unspecified cerebral artery
  • I63.511 Cerebral infarction due to unspecified occlusion or stenosis of right middle cerebral artery
  • I63.512 Cerebral infarction due to unspecified occlusion or stenosis of left middle cerebral artery
  • I63.513 Cerebral infarction due to unspecified occlusion or stenosis of bilateral middle cerebral arteries
  • I63.519 Cerebral infarction due to unspecified occlusion or stenosis of unspecified middle cerebral artery
  • I63.521 Cerebral infarction due to unspecified occlusion or stenosis of right anterior cerebral artery
  • I63.522 Cerebral infarction due to unspecified occlusion or stenosis of left anterior cerebral artery
  • I63.523 Cerebral infarction due to unspecified occlusion or stenosis of bilateral anterior cerebral arteries
  • I63.529 Cerebral infarction due to unspecified occlusion or stenosis of unspecified anterior cerebral artery
  • I63.531 Cerebral infarction due to unspecified occlusion or stenosis of right posterior cerebral artery
  • I63.532 Cerebral infarction due to unspecified occlusion or stenosis of left posterior cerebral artery
  • I63.533 Cerebral infarction due to unspecified occlusion or stenosis of bilateral posterior cerebral arteries
  • I63.539 Cerebral infarction due to unspecified occlusion or stenosis of unspecified posterior cerebral artery
  • I63.541 Cerebral infarction due to unspecified occlusion or stenosis of right cerebellar artery
  • I63.542 Cerebral infarction due to unspecified occlusion or stenosis of left cerebellar artery
  • I63.543 Cerebral infarction due to unspecified occlusion or stenosis of bilateral cerebellar arteries
  • I63.549 Cerebral infarction due to unspecified occlusion or stenosis of unspecified cerebellar artery
  • I63.59 Cerebral infarction due to unspecified occlusion or stenosis of other cerebral artery
  • I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
  • I63.81 Other cerebral infarction due to occlusion or stenosis of small artery
  • I63.89 Other cerebral infarction
  • I63.9 Cerebral infarction, unspecified
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction11 codes
  • I65.01 Occlusion and stenosis of right vertebral artery
  • I65.02 Occlusion and stenosis of left vertebral artery
  • I65.03 Occlusion and stenosis of bilateral vertebral arteries
  • I65.09 Occlusion and stenosis of unspecified vertebral artery
  • I65.1 Occlusion and stenosis of basilar artery
  • I65.21 Occlusion and stenosis of right carotid artery
  • I65.22 Occlusion and stenosis of left carotid artery
  • I65.23 Occlusion and stenosis of bilateral carotid arteries
  • I65.29 Occlusion and stenosis of unspecified carotid artery
  • I65.8 Occlusion and stenosis of other precerebral arteries
  • I65.9 Occlusion and stenosis of unspecified precerebral artery
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction15 codes
  • I66.01 Occlusion and stenosis of right middle cerebral artery
  • I66.02 Occlusion and stenosis of left middle cerebral artery
  • I66.03 Occlusion and stenosis of bilateral middle cerebral arteries
  • I66.09 Occlusion and stenosis of unspecified middle cerebral artery
  • I66.11 Occlusion and stenosis of right anterior cerebral artery
  • I66.12 Occlusion and stenosis of left anterior cerebral artery
  • I66.13 Occlusion and stenosis of bilateral anterior cerebral arteries
  • I66.19 Occlusion and stenosis of unspecified anterior cerebral artery
  • I66.21 Occlusion and stenosis of right posterior cerebral artery
  • I66.22 Occlusion and stenosis of left posterior cerebral artery
  • I66.23 Occlusion and stenosis of bilateral posterior cerebral arteries
  • I66.29 Occlusion and stenosis of unspecified posterior cerebral artery
  • I66.3 Occlusion and stenosis of cerebellar arteries
  • I66.8 Occlusion and stenosis of other cerebral arteries
  • I66.9 Occlusion and stenosis of unspecified cerebral artery
I67 Other cerebrovascular diseases5 codes
  • I67.81 Acute cerebrovascular insufficiency
  • I67.82 Cerebral ischemia
  • I67.841 Reversible cerebrovascular vasoconstriction syndrome
  • I67.848 Other cerebrovascular vasospasm and vasoconstriction
  • I67.89 Other cerebrovascular disease
ICD-10-PCS

Procedure Codes 10 codes · 5 categories

3E03 Administration, Physiological Systems and Anatomical Regions, Introduction2 codes
  • 3E03017 Introduction of Other Thrombolytic into Peripheral Vein, Open Approach
  • 3E03317 Introduction of Other Thrombolytic into Peripheral Vein, Percutaneous Approach
3E04 Administration, Physiological Systems and Anatomical Regions, Introduction2 codes
  • 3E04017 Introduction of Other Thrombolytic into Central Vein, Open Approach
  • 3E04317 Introduction of Other Thrombolytic into Central Vein, Percutaneous Approach
3E05 Administration, Physiological Systems and Anatomical Regions, Introduction2 codes
  • 3E05017 Introduction of Other Thrombolytic into Peripheral Artery, Open Approach
  • 3E05317 Introduction of Other Thrombolytic into Peripheral Artery, Percutaneous Approach
3E06 Administration, Physiological Systems and Anatomical Regions, Introduction2 codes
  • 3E06017 Introduction of Other Thrombolytic into Central Artery, Open Approach
  • 3E06317 Introduction of Other Thrombolytic into Central Artery, Percutaneous Approach
3E08 Administration, Physiological Systems and Anatomical Regions, Introduction2 codes
  • 3E08017 Introduction of Other Thrombolytic into Heart, Open Approach
  • 3E08317 Introduction of Other Thrombolytic into Heart, Percutaneous Approach

Frequently Asked Questions

What is MS-DRG 61?

MS-DRG 61 (Ischemic Stroke, Precerebral Occlusion or Transient Ischemia with Thrombolytic Agent with MCC) is a medical DRG in MDC 01 (Diseases & Disorders of the Nervous System). Its FY 2026 relative weight is 2.7571 with a geometric mean length of stay of 4.7 days.

What is the difference between DRG 61, 62, 63?

All 3 share the same base category; the severity of secondary diagnoses separates them: 61 (with MCC), 62 (with CC), 63 (without CC/MCC). A major complication or comorbidity (MCC) places the case in the highest-weighted DRG of the family; a CC in the middle; neither in the lowest.

How many diagnosis codes group to DRG 61?

130 ICD-10-CM principal diagnosis codes group to this DRG, spanning 6 three-character categories.

What is the relative weight of DRG 61?

The FY 2026 relative weight of this DRG is 2.7571, meaning reimbursement of roughly 2.76 times the average Medicare inpatient case. Multiply by a hospital's blended base rate for the approximate payment.

← PreviousDRG 60 – Multiple Sclerosis and Cerebellar Ataxia without CC/MCC
Source: CMS ICD-10 MS-DRG v43.0 Definitions Manual and the FY 2026 IPPS Final Rule (Table 5), effective October 1, 2025 through September 30, 2026. We publish the DRG assignments as CMS defines them and add the navigation, search, and code links.