MS-DRG · FY 2026 v43.0

MS-DRG 288 – Acute and Subacute Endocarditis with MCC

A Medical DRG in MDC 05 (Diseases & Disorders of the Circulatory System). Inpatient cases group to DRG 288 when the ICD-10-CM principal diagnosis is one of the 5 codes listed below and a secondary diagnosis on the major complication or comorbidity (MCC) list is present. Its FY 2026 relative weight is 2.7062 with a geometric mean length of stay of 7.5 days.

Medical DRG – assigned by principal diagnosis✓ Official CMS v43.0 dataset
2.7062
Relative Weight
7.5
Geometric Mean LOS (days)
9.7
Arithmetic Mean LOS (days)
5
Principal Diagnosis Codes

Severity family

DRG 288with MCCWeight 2.7062 · GMLOS 7.5 daysDRG 289with CCWeight 1.7069 · GMLOS 5.2 daysDRG 290without CC/MCCWeight 0.9297 · GMLOS 2.9 days
How a case is assigned to DRG 288

The grouper first assigns the case to MDC 05 from the principal diagnosis and finds no qualifying operating-room procedure (this is a Medical DRG; ICD-10-PCS codes do not drive assignment here), then applies the severity split from secondary diagnoses: with MCC → 288; with CC → 289; without CC/MCC → 290.

ICD-10-CM

Principal Diagnosis Codes 5 codes · 4 categories

A39 Meningococcal infection1 code
  • A39.51 Meningococcal endocarditis
A52 Late syphilis1 code
  • A52.03 Syphilitic endocarditis
B37 Candidiasis1 code
  • B37.6 Candidal endocarditis
I33 Acute and subacute endocarditis2 codes
  • I33.0 Acute and subacute infective endocarditis
  • I33.9 Acute and subacute endocarditis, unspecified
ICD-10-PCS

Procedure Codes

Procedure codes do not drive assignment for this DRG. DRG 288 is a Medical DRG, assigned from the principal diagnosis above.

Frequently Asked Questions

What is MS-DRG 288?

MS-DRG 288 (Acute and Subacute Endocarditis with MCC) is a medical DRG in MDC 05 (Diseases & Disorders of the Circulatory System). Its FY 2026 relative weight is 2.7062 with a geometric mean length of stay of 7.5 days.

What is the difference between DRG 288, 289, 290?

All 3 share the same base category; the severity of secondary diagnoses separates them: 288 (with MCC), 289 (with CC), 290 (without CC/MCC). A major complication or comorbidity (MCC) places the case in the highest-weighted DRG of the family; a CC in the middle; neither in the lowest.

How many diagnosis codes group to DRG 288?

5 ICD-10-CM principal diagnosis codes group to this DRG, spanning 4 three-character categories.

What is the relative weight of DRG 288?

The FY 2026 relative weight of this DRG is 2.7062, meaning reimbursement of roughly 2.71 times the average Medicare inpatient case. Multiply by a hospital's blended base rate for the approximate payment.

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Source: CMS ICD-10 MS-DRG v43.0 Definitions Manual and the FY 2026 IPPS Final Rule (Table 5), effective October 1, 2025 through September 30, 2026. We publish the DRG assignments as CMS defines them and add the navigation, search, and code links.