XXE Measurement - Physiological Systems ICD-10-PCS
The XXE code range contains 19 ICD-10-PCS codes for Measurement procedures on the physiological systems. 18 of the codes are billable and valid for inpatient claim submission in fiscal year 2027.
Root Operation Definition
Measurement: Determining the level of a physiological or physical function at a point in time.
Codes in the XXE Range 19 codes · 18 billable
- XXE New Technology, Physiological Systems, MeasurementNon-billable header
- XXE0X07 Measurement of Intracranial Vascular Activity, Computer-aided Assessment, New Technology Group 7
- XXE0X1A Measurement of Intracranial Cerebrospinal Fluid Flow, Computer-aided Triage and Notification, New Technology Group 10
- XXE0X48 Measurement of Brain Electrical Activity, Computer-aided Semiologic Analysis, New Technology Group 8
- XXE2X19 Measurement of Cardiac Output, Computer-aided Assessment, New Technology Group 9
- XXE2XHC Measurement of Cardiac Conduction Mechanism, Computer-aided Mapping for Planning, New Technology Group 12 New
- XXE3X27 Measurement of Pulmonary Artery Flow, Computer-aided Triage and Notification, New Technology Group 7
- XXE3X58 Measurement of Coronary Artery Flow, Quantitative Flow Ratio Analysis, New Technology Group 8
- XXE3X68 Measurement of Coronary Artery Flow, Computer-aided Valve Modeling and Notification, New Technology Group 8
- XXE5X2A Measurement of Infection, Phenotypic Fully Automated Rapid Susceptibility Technology with Controlled Inoculum, New Technology Group 10
- XXE5X38 Measurement of Infection, Whole Blood Reverse Transcription and Quantitative Real-time Polymerase Chain Reaction, New Technology Group 8
- XXE5X4A Measurement of Infection, Positive Blood Culture Small Molecule Sensor Array Technology, New Technology Group 10
- XXE5X5A Measurement of Immune Response, Whole Blood Cellular Assessment via Microfluidic Deformability, New Technology Group 10
- XXE5XBB Measurement of Infection and Immune Response, Gene Expression Testing System, New Technology Group 11
- XXE5XV7 Measurement of Infection, Serum/Plasma Nanoparticle Fluorescence SARS-CoV-2 Antibody Detection, New Technology Group 7
- XXE5XY9 Measurement of Infection, Other Positive Blood/Isolated Colonies Bimodal Phenotypic Susceptibility Technology, New Technology Group 9
- XXE97U7 Measurement of Infection, Nasopharyngeal Fluid SARS-CoV-2 Polymerase Chain Reaction, New Technology Group 7
- XXEZXAB Measurement of Macronutrient Content, Computer-aided Assessment for Nutrition Management, New Technology Group 11
- XXEZXCB Measurement of Infection, Computer-aided Triage and Notification, New Technology Group 11
About the XXE Code Range
These procedures measure a function or physical finding at a point in time, including brain electrical activity, artery flow, infection, and macronutrient content.
The fourth character identifies Central Nervous, Cardiac, Arterial, Circulatory, Nose, or None. The fifth separates External procedures from those using instrumentation through a natural or artificial opening. The sixth identifies the substance or technology, such as coronary artery flow analysis, infection testing, or computer-aided nutrition assessment. The seventh identifies the New Technology Group.
FY 2027 changes: The FY 2027 ICD-10-PCS update, effective October 1, 2026, added XXE2XHC and deleted XXE5XR7 and XXE5XT7.
Questions About This Page
How many billable codes are in the XXE range?
Of the 19 codes in this range, 18 are billable and valid for inpatient claim submission from October 1, 2026 through September 30, 2027. Table header codes group them but cannot be reported on claims.
What does the XXE range classify?
The range classifies Measurement procedures, determining the level of a physiological or physical function at a point in time, performed on the physiological systems. Each code adds the body part, approach, device, and qualifier in characters four through seven, and links to its own reference page.
Related References
Source: CMS FY 2027 ICD-10-PCS order file and code tables, effective October 1, 2026 through September 30, 2027.
