XHR Replacement - Skin, Subcutaneous Tissue, Fascia and Breast ICD-10-PCS
The XHR code range contains 10 ICD-10-PCS codes for Replacement procedures on the skin, subcutaneous tissue, fascia and breast. 9 of the codes are billable and valid for inpatient claim submission in fiscal year 2026.
Root Operation Definition
Replacement: Putting in or on biological or synthetic material that physically takes the place and/or function of all or a portion of a body part.
Codes in the XHR Range 10 codes · 9 billable
- XHR New Technology, Skin, Subcutaneous Tissue, Fascia and Breast, ReplacementNon-billable header
- XHR0XGA Replacement of Head and Neck Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10 New
- XHR1XGA Replacement of Chest Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10 New
- XHR2XGA Replacement of Abdomen Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10 New
- XHR3XGA Replacement of Back Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10 New
- XHR4XGA Replacement of Right Upper Extremity Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10 New
- XHR5XGA Replacement of Left Upper Extremity Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10 New
- XHR6XGA Replacement of Right Lower Extremity Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10 New
- XHR7XGA Replacement of Left Lower Extremity Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10 New
- XHRPXF7 Replacement of Skin with Bioengineered Allogeneic Construct, External Approach, New Technology Group 7
About the XHR Code Range
The ICD-10-PCS root operation Replacement (code XHR) within the New Technology section refers to substituting a body part with a material that restores its function. This operation specifically applies to replacing skin, subcutaneous tissue, fascia, and breast using advanced bioengineered or genetically engineered cell therapies.
The provided codes illustrate different instances of replacement procedures using cutting-edge treatments like Prademagene Zamikeracel, a genetically engineered autologous cell therapy, applied via an external approach to various anatomical regions such as the head and neck (XHR0XGA), chest (XHR1XGA), and all four extremities. Additionally, the use of a bioengineered allogeneic construct for skin replacement is recorded by code XHRPXF7. These codes enable precise documentation of innovative skin and tissue replacement procedures, reflecting the growing role of regenerative therapies in modern medical practice.
Questions About This Page
How many billable codes are in the XHR range?
Of the 10 codes in this range, 9 are billable and valid for inpatient claim submission from October 1, 2025 through September 30, 2026. Table header codes group them but cannot be reported on claims.
What does the XHR range classify?
The range classifies Replacement procedures, putting in or on biological or synthetic material that physically takes the place and/or function of all or a portion of a body part, performed on the skin, subcutaneous tissue, fascia and breast. Each code adds the body part, approach, device, and qualifier in characters four through seven, and links to its own reference page.
Related References
Source: CMS FY 2026 ICD-10-PCS order file and code tables, effective October 1, 2025 through September 30, 2026.
