6A5 Pheresis - Physiological Systems ICD-10-PCS
The 6A5 code range contains 13 ICD-10-PCS codes for Pheresis procedures on the physiological systems. 12 of the codes are billable and valid for inpatient claim submission in fiscal year 2026.
Root Operation Definition
Pheresis: Extracorporeal separation of blood products.
Codes in the 6A5 Range 13 codes · 12 billable
- 6A5 Extracorporeal or Systemic Therapies, Physiological Systems, PheresisNon-billable header
- 6A550Z0 Pheresis of Erythrocytes, Single
- 6A550Z1 Pheresis of Leukocytes, Single
- 6A550Z2 Pheresis of Platelets, Single
- 6A550Z3 Pheresis of Plasma, Single
- 6A550ZT Pheresis of Cord Blood Stem Cells, Single
- 6A550ZV Pheresis of Hematopoietic Stem Cells, Single
- 6A551Z0 Pheresis of Erythrocytes, Multiple
- 6A551Z1 Pheresis of Leukocytes, Multiple
- 6A551Z2 Pheresis of Platelets, Multiple
- 6A551Z3 Pheresis of Plasma, Multiple
- 6A551ZT Pheresis of Cord Blood Stem Cells, Multiple
- 6A551ZV Pheresis of Hematopoietic Stem Cells, Multiple
About the 6A5 Code Range
The ICD-10-PCS root operation Pheresis (code 6A5) refers to a procedure involving the extracorporeal removal or separation of specific physiological components from the blood or blood products. This is classified under Extracorporeal or Systemic Therapies.
In practice, pheresis entails extracting targeted elements such as erythrocytes, leukocytes, platelets, plasma, or specialized cells like cord blood stem cells and hematopoietic stem cells. The ICD-10-PCS codes further distinguish whether the procedure is performed once (single) or repeatedly (multiple) in the same episode. For example, code 6A550Z0 denotes the single pheresis of erythrocytes, while 6A551Z2 corresponds to multiple pheresis sessions of platelets. These codes help accurately capture the specific type and frequency of pheresis, essential for correct procedural documentation and billing in systemic therapy contexts.
Questions About This Page
How many billable codes are in the 6A5 range?
Of the 13 codes in this range, 12 are billable and valid for inpatient claim submission from October 1, 2025 through September 30, 2026. Table header codes group them but cannot be reported on claims.
What does the 6A5 range classify?
The range classifies Pheresis procedures, extracorporeal separation of blood products, performed on the physiological systems. Each code adds the body part, approach, device, and qualifier in characters four through seven, and links to its own reference page.
Related References
Source: CMS FY 2026 ICD-10-PCS order file and code tables, effective October 1, 2025 through September 30, 2026.
