ICD-10-PCS Tabular Index · Section 0 · FY 2026 00R

00R Replacement - Central Nervous System and Cranial Nerves ICD-10-PCS

The 00R code range contains 97 ICD-10-PCS codes for Replacement procedures on the central nervous system and cranial nerves. 96 of the codes are billable and valid for inpatient claim submission in fiscal year 2026.

✓ Built from the official CMS FY 2026 datasetEffective Oct 1, 2025 – Sep 30, 2026
97
Procedure Codes
96
Billable Codes
00R
Characters 1–3
00
Parent Body System

Root Operation Definition

Replacement: Putting in or on biological or synthetic material that physically takes the place and/or function of all or a portion of a body part.

ICD-10-PCS

Codes in the 00R Range 97 codes · 96 billable

97 of 97 shown
  • 00R Central Nervous System and Cranial Nerves, ReplacementNon-billable header
  • 00R107Z Replacement of Cerebral Meninges with Autologous Tissue Substitute, Open Approach
  • 00R10JZ Replacement of Cerebral Meninges with Synthetic Substitute, Open Approach
  • 00R10KZ Replacement of Cerebral Meninges with Nonautologous Tissue Substitute, Open Approach
  • 00R147Z Replacement of Cerebral Meninges with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00R14JZ Replacement of Cerebral Meninges with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00R14KZ Replacement of Cerebral Meninges with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00R207Z Replacement of Dura Mater with Autologous Tissue Substitute, Open Approach
  • 00R20JZ Replacement of Dura Mater with Synthetic Substitute, Open Approach
  • 00R20KZ Replacement of Dura Mater with Nonautologous Tissue Substitute, Open Approach
  • 00R247Z Replacement of Dura Mater with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00R24JZ Replacement of Dura Mater with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00R24KZ Replacement of Dura Mater with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00R607Z Replacement of Cerebral Ventricle with Autologous Tissue Substitute, Open Approach
  • 00R60JZ Replacement of Cerebral Ventricle with Synthetic Substitute, Open Approach
  • 00R60KZ Replacement of Cerebral Ventricle with Nonautologous Tissue Substitute, Open Approach
  • 00R647Z Replacement of Cerebral Ventricle with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00R64JZ Replacement of Cerebral Ventricle with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00R64KZ Replacement of Cerebral Ventricle with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RF07Z Replacement of Olfactory Nerve with Autologous Tissue Substitute, Open Approach
  • 00RF0JZ Replacement of Olfactory Nerve with Synthetic Substitute, Open Approach
  • 00RF0KZ Replacement of Olfactory Nerve with Nonautologous Tissue Substitute, Open Approach
  • 00RF47Z Replacement of Olfactory Nerve with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RF4JZ Replacement of Olfactory Nerve with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00RF4KZ Replacement of Olfactory Nerve with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RG07Z Replacement of Optic Nerve with Autologous Tissue Substitute, Open Approach
  • 00RG0JZ Replacement of Optic Nerve with Synthetic Substitute, Open Approach
  • 00RG0KZ Replacement of Optic Nerve with Nonautologous Tissue Substitute, Open Approach
  • 00RG47Z Replacement of Optic Nerve with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RG4JZ Replacement of Optic Nerve with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00RG4KZ Replacement of Optic Nerve with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RH07Z Replacement of Oculomotor Nerve with Autologous Tissue Substitute, Open Approach
  • 00RH0JZ Replacement of Oculomotor Nerve with Synthetic Substitute, Open Approach
  • 00RH0KZ Replacement of Oculomotor Nerve with Nonautologous Tissue Substitute, Open Approach
  • 00RH47Z Replacement of Oculomotor Nerve with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RH4JZ Replacement of Oculomotor Nerve with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00RH4KZ Replacement of Oculomotor Nerve with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RJ07Z Replacement of Trochlear Nerve with Autologous Tissue Substitute, Open Approach
  • 00RJ0JZ Replacement of Trochlear Nerve with Synthetic Substitute, Open Approach
  • 00RJ0KZ Replacement of Trochlear Nerve with Nonautologous Tissue Substitute, Open Approach
  • 00RJ47Z Replacement of Trochlear Nerve with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RJ4JZ Replacement of Trochlear Nerve with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00RJ4KZ Replacement of Trochlear Nerve with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RK07Z Replacement of Trigeminal Nerve with Autologous Tissue Substitute, Open Approach
  • 00RK0JZ Replacement of Trigeminal Nerve with Synthetic Substitute, Open Approach
  • 00RK0KZ Replacement of Trigeminal Nerve with Nonautologous Tissue Substitute, Open Approach
  • 00RK47Z Replacement of Trigeminal Nerve with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RK4JZ Replacement of Trigeminal Nerve with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00RK4KZ Replacement of Trigeminal Nerve with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RL07Z Replacement of Abducens Nerve with Autologous Tissue Substitute, Open Approach
  • 00RL0JZ Replacement of Abducens Nerve with Synthetic Substitute, Open Approach
  • 00RL0KZ Replacement of Abducens Nerve with Nonautologous Tissue Substitute, Open Approach
  • 00RL47Z Replacement of Abducens Nerve with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RL4JZ Replacement of Abducens Nerve with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00RL4KZ Replacement of Abducens Nerve with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RM07Z Replacement of Facial Nerve with Autologous Tissue Substitute, Open Approach
  • 00RM0JZ Replacement of Facial Nerve with Synthetic Substitute, Open Approach
  • 00RM0KZ Replacement of Facial Nerve with Nonautologous Tissue Substitute, Open Approach
  • 00RM47Z Replacement of Facial Nerve with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RM4JZ Replacement of Facial Nerve with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00RM4KZ Replacement of Facial Nerve with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RN07Z Replacement of Acoustic Nerve with Autologous Tissue Substitute, Open Approach
  • 00RN0JZ Replacement of Acoustic Nerve with Synthetic Substitute, Open Approach
  • 00RN0KZ Replacement of Acoustic Nerve with Nonautologous Tissue Substitute, Open Approach
  • 00RN47Z Replacement of Acoustic Nerve with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RN4JZ Replacement of Acoustic Nerve with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00RN4KZ Replacement of Acoustic Nerve with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RP07Z Replacement of Glossopharyngeal Nerve with Autologous Tissue Substitute, Open Approach
  • 00RP0JZ Replacement of Glossopharyngeal Nerve with Synthetic Substitute, Open Approach
  • 00RP0KZ Replacement of Glossopharyngeal Nerve with Nonautologous Tissue Substitute, Open Approach
  • 00RP47Z Replacement of Glossopharyngeal Nerve with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RP4JZ Replacement of Glossopharyngeal Nerve with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00RP4KZ Replacement of Glossopharyngeal Nerve with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RQ07Z Replacement of Vagus Nerve with Autologous Tissue Substitute, Open Approach
  • 00RQ0JZ Replacement of Vagus Nerve with Synthetic Substitute, Open Approach
  • 00RQ0KZ Replacement of Vagus Nerve with Nonautologous Tissue Substitute, Open Approach
  • 00RQ47Z Replacement of Vagus Nerve with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RQ4JZ Replacement of Vagus Nerve with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00RQ4KZ Replacement of Vagus Nerve with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RR07Z Replacement of Accessory Nerve with Autologous Tissue Substitute, Open Approach
  • 00RR0JZ Replacement of Accessory Nerve with Synthetic Substitute, Open Approach
  • 00RR0KZ Replacement of Accessory Nerve with Nonautologous Tissue Substitute, Open Approach
  • 00RR47Z Replacement of Accessory Nerve with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RR4JZ Replacement of Accessory Nerve with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00RR4KZ Replacement of Accessory Nerve with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RS07Z Replacement of Hypoglossal Nerve with Autologous Tissue Substitute, Open Approach
  • 00RS0JZ Replacement of Hypoglossal Nerve with Synthetic Substitute, Open Approach
  • 00RS0KZ Replacement of Hypoglossal Nerve with Nonautologous Tissue Substitute, Open Approach
  • 00RS47Z Replacement of Hypoglossal Nerve with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RS4JZ Replacement of Hypoglossal Nerve with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00RS4KZ Replacement of Hypoglossal Nerve with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RT07Z Replacement of Spinal Meninges with Autologous Tissue Substitute, Open Approach
  • 00RT0JZ Replacement of Spinal Meninges with Synthetic Substitute, Open Approach
  • 00RT0KZ Replacement of Spinal Meninges with Nonautologous Tissue Substitute, Open Approach
  • 00RT47Z Replacement of Spinal Meninges with Autologous Tissue Substitute, Percutaneous Endoscopic Approach
  • 00RT4JZ Replacement of Spinal Meninges with Synthetic Substitute, Percutaneous Endoscopic Approach
  • 00RT4KZ Replacement of Spinal Meninges with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach

About the 00R Code Range

The ICD-10-PCS root operation Replacement (code 00R) involves taking out a body part and putting in another to restore function. In the Medical and Surgical section, this operation specifically applies to the Central Nervous System and Cranial Nerves.

Replacement procedures for this system include substituting structures like the Cerebral Meninges, Dura Mater, and various cranial nerves such as the Olfactory, Optic, Facial, and Acoustic Nerves. These replacements can use different substitutes including Autologous Tissue (patient's own tissue), Synthetic Substitutes, or Nonautologous Tissue (donor tissue). Approaches vary from more invasive Open Approaches to less invasive Percutaneous Endoscopic Approaches. For example, code 00R107Z describes open replacement of cerebral meninges using autologous tissue, while 00RK4JZ refers to endoscopic replacement of the trigeminal nerve with a synthetic substitute. These precise codes allow documentation of intricate neurosurgical restorative procedures.

Questions About This Page

How many billable codes are in the 00R range?

Of the 97 codes in this range, 96 are billable and valid for inpatient claim submission from October 1, 2025 through September 30, 2026. Table header codes group them but cannot be reported on claims.

What does the 00R range classify?

The range classifies Replacement procedures, putting in or on biological or synthetic material that physically takes the place and/or function of all or a portion of a body part, performed on the central nervous system and cranial nerves. Each code adds the body part, approach, device, and qualifier in characters four through seven, and links to its own reference page.

Related References

All ICD-10-PCS SectionsAll of Medical and Surgical (0)All of Body System 00ICD-10-PCS Code LookupICD-10-CM Codes ListMS-DRG ReferenceMedicare Code Edits

Source: CMS FY 2026 ICD-10-PCS order file and code tables, effective October 1, 2025 through September 30, 2026.