X053X4BDestruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11

  • Billable / Specific Code
ICD-10-PCS X053X4B
CMS Source: FY 2027 ICD-10-PCS dataset. Effective Oct 1, 2026 – Sep 30, 2027.FacebookXLinkedInPrint

X053X4B is a billable ICD-10-PCS procedure code for Destruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to 13 MS-DRGs. The root operation Destruction involves physical eradication of all or a portion of a body part by the direct use of energy, force, or a destructive agent. In AHRQ's Clinical Classifications Software (CCSR), this procedure falls under CNS excision procedures.

Code Identity

ICD-10-PCS Code
X053X4B
Billable Status
Yes — Valid for Submission
Code Describes
Destruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11
Short Description
Destruc Brain w Focused Ultrasound, Extern, New Tech 11
Parent Code
X05 New Technology, Nervous System, Destruction

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

PositionDesignationValueMeaning
1SectionXNew Technology
2Body System0Nervous System
3Operation5Destruction
4BodyPart3Brain
5ApproachXExternal
6Device/Substance/Technology4Focused Ultrasound Therapy
7QualifierBNew Technology Group 11

In the ICD-10-PCS Alphabetic Index

These FY 2027 ICD-10-PCS Alphabetic Index entries lead to this code:

Destruction, Brain, Focused Ultrasound Therapy
Direct entry for this code
Focused Ultrasound Therapy, Destruction, Brain
Direct entry for this code
New Technology, Destruction, Brain, Focused Ultrasound Therapy
Direct entry for this code
Anatomy or device term that leads here
Anatomy or device term that leads here
Anatomy or device term that leads here

To code focused ultrasound therapy of the brain destruction, open the FY 2027 ICD-10-PCS Alphabetic Index at Focused Ultrasound Therapy, then the subterms Destruction, Brain. The entry lists X053X4B directly as a complete, billable code.

Browse the full ICD-10-PCS Alphabetic Index →

Clinical Classification (CCSR)

AHRQ groups this procedure code into these clinical categories.

CNS007
CNS excision procedures
Clinical domain: Central Nervous System Procedures

Code History

Replaces previously assigned code(s):
  • 00503ZZ — Destruction of Brain, Percutaneous Approach

Similar Procedure Codes

Questions About X053X4B

Is X053X4B a billable code?

Yes. This is a complete seven-character ICD-10-PCS code, specific enough to report Destruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11 on inpatient claims from October 1, 2026 through September 30, 2027.

What is the ICD-10-PCS code for focused ultrasound therapy of the brain destruction?

The FY 2027 ICD-10-PCS Alphabetic Index entry Focused Ultrasound Therapy, Destruction, Brain is a direct entry for X053X4B, Destruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11, billable on inpatient claims from October 1, 2026 through September 30, 2027.

What do the characters in X053X4B mean?

The code breaks down character by character: the 1st character X is the Section (New Technology); the 2nd character 0 is the Body System (Nervous System); the 3rd character 5 is the Operation (Destruction); the 4th character 3 is the BodyPart (Brain); the 5th character X is the Approach (External); the 6th character 4 is the Device/Substance/Technology (Focused Ultrasound Therapy); the 7th character B is the Qualifier (New Technology Group 11).

What MS-DRG does X053X4B group to?

On an inpatient stay, Destruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11 maps to MS-DRGs 025, 026, 027, 820, 821, 822, 826, 827, 828, 907, 908, 909, 955, with relative weights from 1.1267 to 6.5257. The MS-DRG sets the fixed Medicare payment for the stay.