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  6. X053X4B
  • Version 2026
  • Billable Code
  • New Code

2026 ICD-10-PCS Procedure Code X053X4B

Destruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11

ICD-10-PCS Code:
X053X4B
ICD-10-PCS Code for:
Destruc Brain w Focused Ultrasound, Extern, New Tech 11
Is Billable?
Yes - Valid for Submission
Code Navigator:

X053X4B is a billable procedure code used to specify the performance of destruction of brain using focused ultrasound therapy, external approach, new technology group 11. The code is valid for the year 2026 for the submission of HIPAA-covered transactions. The procedure code involves physical eradication of all or a portion of a body part by the direct use of energy, force, or a destructive agent. Procedure code explanation: none of the body part is physically taken out fulguration of rectal polyp, cautery of skin lesion

X053X4B PCS Table

In an PCS table each code is represented by up seven alphanumeric characters, with each character in the table respresenting different aspects of the procedure. In the table provided below, each row represents an individual character and includes information about the character's position, designation, label, and procedure notes. For this PCS table the procedure code is in the new technology section and is part of the nervous system body system, classified under destruction operation. The applicable bodypart for this procedure code is brain.

Position Designation Character Label Procedures Notes
1 Section X New Technology
2 Body System 0 Nervous System
3 Operation 5 Destruction

Involves:
Physical eradication of all or a portion of a body part by the direct use of energy, force, or a destructive agent

Explanation:
None of the body part is physically taken out

Includes:
  • Fulguration of rectal polyp, cautery of skin lesion
4 BodyPart 3 Brain  
5 Approach X External

Involves:
Procedures performed directly on the skin or mucous membrane and procedures performed indirectly by the application of external force through the skin or mucous membrane
6 Device/Substance/Technology 4 Focused Ultrasound Therapy
7 Qualifier B New Technology Group 11

New 2026 ICD-10-PCS Code

X053X4B is new to ICD-10-PCS code set for the FY 2026, effective October 1, 2025.

Replacement Code

X053X4B replaces the following previously assigned ICD-10-PCS code(s):

  • 00503ZZ - Destruction of Brain, Percutaneous Approach
  • 00503ZZ - Destruction of Brain, Percutaneous Approach
  • 00503ZZ - Destruction of Brain, Percutaneous Approach
  • 00503ZZ - Destruction of Brain, Percutaneous Approach
  • 00503ZZ - Destruction of Brain, Percutaneous Approach
  • 00503ZZ - Destruction of Brain, Percutaneous Approach
  • 00503ZZ - Destruction of Brain, Percutaneous Approach

Other ICD-10-PCS Codes Used for Destruction Brain

  • X05 New Technology, Nervous System, Destruction

  • X051329 Destruction of Renal Sympathetic Nerve(s) using Ultrasound Ablation, Percutaneous Approach, New Technology Group 9

  • X05133A Destruction of Renal Sympathetic Nerve(s) using Radiofrequency Ablation, Percutaneous Approach, New Technology Group 10

  • X05233B Destruction of Thoracic Sympathetic Nerve, Cardiac Plexus using Radiofrequency Ablation, Percutaneous Approach, New Technology Group 11

What is ICD-10-PCS?

The ICD-10 Procedure Coding System (ICD-10-PCS) is a catalog of procedural codes used by medical professionals for hospital inpatient healthcare settings. The Centers for Medicare and Medicaid Services (CMS) maintain the catalog in the U.S. releasing yearly updates. The 2026 ICD-10-PCS codes are to be used for discharges occurring from October 1, 2025 through September 30, 2026.

Each ICD-10-PCS code has a structure of seven alphanumeric characters and contains no decimals. The first character defines the major "section". Depending on the "section" the second through seventh characters mean different things.