X053X4BDestruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11

ICD-10-PCS X053X4B
CMS Source: FY 2026 ICD-10-PCS dataset. Effective Oct 1, 2025 – Sep 30, 2026.FacebookXLinkedInPrint

X053X4B is a billable ICD-10-PCS procedure code for Destruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to 12 MS-DRGs. The root operation Destruction involves physical eradication of all or a portion of a body part by the direct use of energy, force, or a destructive agent.

Code Identity

ICD-10-PCS Code
X053X4B
Billable Status
Yes — Valid for Submission
Code Describes
Destruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11
Parent Code
X05 New Technology, Nervous System, Destruction
Short Description
Destruc Brain w Focused Ultrasound, Extern, New Tech 11

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

PositionDesignationValueMeaning
1SectionXNew Technology
2Body System0Nervous System
3Operation5Destruction
4BodyPart3Brain
5ApproachXExternal
6Device/Substance/Technology4Focused Ultrasound Therapy
7QualifierBNew Technology Group 11

Code History

FY 2026New code, effective October 1, 2025.
Replaces previously assigned code(s):
  • 00503ZZ — Destruction of Brain, Percutaneous Approach

Similar Procedure Codes

Questions About X053X4B

Is X053X4B a billable code?

Yes. X053X4B is a complete seven-character ICD-10-PCS code, specific enough to report Destruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11 on inpatient claims from October 1, 2025 through September 30, 2026.

What do the characters in X053X4B mean?

X053X4B breaks down character by character: the 1st character X is the Section (New Technology); the 2nd character 0 is the Body System (Nervous System); the 3rd character 5 is the Operation (Destruction); the 4th character 3 is the BodyPart (Brain); the 5th character X is the Approach (External); the 6th character 4 is the Device/Substance/Technology (Focused Ultrasound Therapy); the 7th character B is the Qualifier (New Technology Group 11).

What MS-DRG does X053X4B group to?

On an inpatient stay, Destruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11 maps to MS-DRGs 025, 026, 027, 820, 821, 822, 826, 827, 828, 907, 908, 909, with relative weights from 1.2040 to 5.8648. The MS-DRG sets the fixed Medicare payment for the stay.