5A1221ZPerformance of Cardiac Output, Continuous

Extracorporeal or Systemic Assistance and Performance›Physiological Systems›Performance

Billable / Specific Code

ICD-10-PCS 5A1221Z

CMS Source: FY 2027 ICD-10-PCS dataset. Effective Oct 1, 2026 – Sep 30, 2027.

5A1221Z is a billable ICD-10-PCS procedure code for Performance of Cardiac Output, Continuous. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027). The root operation Performance involves completely taking over a physiological function by extracorporeal means. In AHRQ's Clinical Classifications Software (CCSR), this procedure falls under Open heart cardiopulmonary bypass.

Code Identity

ICD-10-PCS Code

5A1221Z

Billable Status

Yes — Valid for Submission

Code Describes

Performance of Cardiac Output, Continuous

Short Description

Performance of Cardiac Output, Continuous

Same as the full description in the CMS dataset.

Parent Code

5A1

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

Position	Designation	Value	Meaning
1	Section	5	Extracorporeal or Systemic Assistance and Performance
2	Body System	A	Physiological Systems
3	Operation	1	Performance
4	BodySystem	2	Cardiac
5	Duration	2	Continuous
6	Function	1	Output
7	Qualifier	Z	No Qualifier

In the ICD-10-PCS Alphabetic Index

These FY 2027 ICD-10-PCS Alphabetic Index entries lead to this code:

Bypass, cardiopulmonary

Direct entry for this code

Performance, Cardiac, Continuous, Output

Leads to this code's table

To code performance of the output continuous cardiac, open the FY 2027 ICD-10-PCS Alphabetic Index at Performance, then the subterms Cardiac, Continuous, Output. The index leads to table 5A1, where the duration, function and qualifier values shown in the breakdown above complete the seven-character code 5A1221Z.

Browse the full ICD-10-PCS Alphabetic Index →

Clinical Classification (CCSR)

AHRQ groups this procedure code into these clinical categories.

ESA008

Open heart cardiopulmonary bypass

Clinical domain: Extracorporeal or Systemic Assistance and Performance

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for this code under the General Equivalence Mappings.

39.61

Extracorporeal circulation auxiliary to open heart surgery

Approximate match.

39.66

Percutaneous cardiopulmonary bypass

Approximate match.

Code History

Replaced in the FY 2027 code set by:

5A1221J — Performance of Cardiac Output, Continuous, Automated

Similar Procedure Codes

Questions About 5A1221Z

Is 5A1221Z a billable code?

Yes. This is a complete seven-character ICD-10-PCS code, specific enough to report Performance of Cardiac Output, Continuous on inpatient claims from October 1, 2026 through September 30, 2027.

What do the characters in 5A1221Z mean?

The code breaks down character by character: the 1st character 5 is the Section (Extracorporeal or Systemic Assistance and Performance); the 2nd character A is the Body System (Physiological Systems); the 3rd character 1 is the Operation (Performance); the 4th character 2 is the BodySystem (Cardiac); the 5th character 2 is the Duration (Continuous); the 6th character 1 is the Function (Output); the 7th character Z is the Qualifier (No Qualifier).

What is the ICD-9-PCS equivalent of 5A1221Z?

Under the General Equivalence Mappings, Performance of Cardiac Output, Continuous crosswalks to ICD-9-PCS 39.61 (Extracorporeal circulation auxiliary to open heart surgery) and 39.66 (Percutaneous cardiopulmonary bypass). The mapping is approximate, so confirm it fits the documentation.