3E0D74ZIntroduction of Serum, Toxoid and Vaccine into Mouth and Pharynx, Via Natural or Artificial Opening

Administration›Physiological Systems and Anatomical Regions›Introduction
  • Billable / Specific Code
ICD-10-PCS 3E0D74Z
CMS Source: FY 2026 ICD-10-PCS dataset. Effective Oct 1, 2025 – Sep 30, 2026.FacebookXLinkedInPrint

3E0D74Z is a billable ICD-10-PCS procedure code for Introduction of Serum, Toxoid and Vaccine into Mouth and Pharynx, Via Natural or Artificial Opening. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products. In AHRQ's Clinical Classifications Software (CCSR), this procedure falls under Vaccinations.

Code Identity

ICD-10-PCS Code
3E0D74Z
Billable Status
Yes — Valid for Submission
Code Describes
Introduction of Serum, Toxoid and Vaccine into Mouth and Pharynx, Via Natural or Artificial Opening
Short Description
Introduce of Serum/Tox/Vaccine into Mouth/Phar, Via Opening
Parent Code
3E0

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

PositionDesignationValueMeaning
1Section3Administration
2Body SystemEPhysiological Systems and Anatomical Regions
3Operation0Introduction
4BodySystem/RegionDMouth and Pharynx
5Approach7Via Natural or Artificial Opening
6Substance4Serum, Toxoid and Vaccine
7QualifierZNo Qualifier

In the ICD-10-PCS Alphabetic Index

These FY 2026 ICD-10-PCS Alphabetic Index entries lead to this code:

Introduction of substance in or on, Mouth
Leads to this code's table
Introduction of substance in or on, Pharynx
Leads to this code's table
Introduction of substance in or on, Mouth, Serum
Leads to this code's table
Introduction of substance in or on, Mouth, Toxoid
Leads to this code's table
Introduction of substance in or on, Mouth, Vaccine
Leads to this code's table
Introduction of substance in or on, Pharynx, Serum
Leads to this code's table
Introduction of substance in or on, Pharynx, Toxoid
Leads to this code's table
Introduction of substance in or on, Mouth, Hypnotics
Leads to this code's table
Introduction of substance in or on, Mouth, Sedatives
Leads to this code's table
Introduction of substance in or on, Pharynx, Vaccine
Leads to this code's table
Introduction of substance in or on, Mouth, Analgesics
Leads to this code's table
Introduction of substance in or on, Pharynx, Hypnotics
Leads to this code's table
Introduction of substance in or on, Pharynx, Sedatives
Leads to this code's table
Introduction of substance in or on, Pharynx, Analgesics
Leads to this code's table
Introduction of substance in or on, Mouth, Antiarrhythmic
Leads to this code's table

Browse the full ICD-10-PCS Alphabetic Index →

Clinical Classification (CCSR)

AHRQ groups this procedure code into these clinical categories.

ADM010
Vaccinations
Clinical domain: Administration of Therapeutic Substances

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for this code under the General Equivalence Mappings.

99.29
Injection or infusion of other therapeutic or prophylactic substance
Approximate match.

Similar Procedure Codes

Questions About 3E0D74Z

Is 3E0D74Z a billable code?

Yes. This is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of Serum, Toxoid and Vaccine into Mouth and Pharynx, Via Natural or Artificial Opening on inpatient claims from October 1, 2025 through September 30, 2026.

What do the characters in 3E0D74Z mean?

The code breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character D is the BodySystem/Region (Mouth and Pharynx); the 5th character 7 is the Approach (Via Natural or Artificial Opening); the 6th character 4 is the Substance (Serum, Toxoid and Vaccine); the 7th character Z is the Qualifier (No Qualifier).

What is the ICD-9-PCS equivalent of 3E0D74Z?

Under the General Equivalence Mappings, Introduction of Serum, Toxoid and Vaccine into Mouth and Pharynx, Via Natural or Artificial Opening crosswalks to ICD-9-PCS 99.29 (Injection or infusion of other therapeutic or prophylactic substance). The mapping is approximate, so confirm it fits the documentation.