3E08316Introduction of Recombinant Human-activated Protein C into Heart, Percutaneous

Administration›Physiological Systems and Anatomical Regions›Introduction

Billable / Specific Code

ICD-10-PCS 3E08316

CMS Source: FY 2026 ICD-10-PCS dataset. Effective Oct 1, 2025 – Sep 30, 2026.

3E08316 is a billable ICD-10-PCS procedure code for Introduction of Recombinant Human-activated Protein C into Heart, Percutaneous. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The root operation Introduction involves putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

Code Identity

ICD-10-PCS Code

3E08316

Billable Status

Yes — Valid for Submission

Code Describes

Introduction of Recombinant Human-activated Protein C into Heart, Percutaneous

Parent Code

3E0

Short Description

Introduction of Recomb Protein C into Heart, Perc

PCS Table Breakdown

Each ICD-10-PCS code is built from seven characters, each an axis of the procedure. Hover or tap the icons for the official CMS definitions.

Position	Designation	Value	Meaning
1	Section	3	Administration
2	Body System	E	Physiological Systems and Anatomical Regions
3	Operation	0	Introduction
4	BodySystem/Region	8	Heart
5	Approach	3	Percutaneous
6	Substance	1	Thrombolytic
7	Qualifier	6	Recombinant Human-activated Protein C

Convert to ICD-9-PCS

Closest ICD-9-PCS equivalents for 3E08316 under the General Equivalence Mappings.

Approximate match.

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Questions About 3E08316

Is 3E08316 a billable code?

Yes. 3E08316 is a complete seven-character ICD-10-PCS code, specific enough to report Introduction of Recombinant Human-activated Protein C into Heart, Percutaneous on inpatient claims from October 1, 2025 through September 30, 2026.

What do the characters in 3E08316 mean?

3E08316 breaks down character by character: the 1st character 3 is the Section (Administration); the 2nd character E is the Body System (Physiological Systems and Anatomical Regions); the 3rd character 0 is the Operation (Introduction); the 4th character 8 is the BodySystem/Region (Heart); the 5th character 3 is the Approach (Percutaneous); the 6th character 1 is the Substance (Thrombolytic); the 7th character 6 is the Qualifier (Recombinant Human-activated Protein C).

What is the ICD-9-PCS equivalent of 3E08316?

Under the General Equivalence Mappings, Introduction of Recombinant Human-activated Protein C into Heart, Percutaneous crosswalks to ICD-9-PCS 11. The mapping is approximate, so confirm it fits the documentation.