MS-DRG · FY 2026 v43.0

MS-DRG 848 – Chemotherapy without Acute Leukemia as Secondary Diagnosis without CC/MCC

A Medical DRG in MDC 17 (Myeloproliferative Diseases & Disorders, Poorly Differentiated Neoplasms). Inpatient cases group to DRG 848 when the ICD-10-CM principal diagnosis is one of the 3 codes listed below and no secondary diagnosis on the CC or MCC lists is present. Its FY 2026 relative weight is 0.8494 with a geometric mean length of stay of 2.6 days.

Medical DRG – assigned by principal diagnosis✓ Official CMS v43.0 dataset
0.8494
Relative Weight
2.6
Geometric Mean LOS (days)
3.3
Arithmetic Mean LOS (days)
3
Principal Diagnosis Codes

Severity family

DRG 846with MCCWeight 2.5925 · GMLOS 5.8 daysDRG 847with CCWeight 1.3082 · GMLOS 3.8 daysDRG 848without CC/MCCWeight 0.8494 · GMLOS 2.6 days
How a case is assigned to DRG 848

The grouper first assigns the case to MDC 17 from the principal diagnosis and finds no qualifying operating-room procedure (this is a Medical DRG; ICD-10-PCS codes do not drive assignment here), then applies the severity split from secondary diagnoses: with MCC → 846; with CC → 847; without CC/MCC → 848.

ICD-10-CM

Principal Diagnosis Codes 3 codes · 2 categories

Z08 Encounter for follow-up examination after completed treatment for malignant neoplasm1 code
  • Z08 Encounter for follow-up examination after completed treatment for malignant neoplasm
Z51 Encounter for other aftercare and medical care2 codes
  • Z51.11 Encounter for antineoplastic chemotherapy
  • Z51.12 Encounter for antineoplastic immunotherapy
ICD-10-PCS

Procedure Codes

Procedure codes do not drive assignment for this DRG. DRG 848 is a Medical DRG, assigned from the principal diagnosis above.

Frequently Asked Questions

What is MS-DRG 848?

MS-DRG 848 (Chemotherapy without Acute Leukemia as Secondary Diagnosis without CC/MCC) is a medical DRG in MDC 17 (Myeloproliferative Diseases & Disorders, Poorly Differentiated Neoplasms). Its FY 2026 relative weight is 0.8494 with a geometric mean length of stay of 2.6 days.

What is the difference between DRG 846, 847, 848?

All 3 share the same base category; the severity of secondary diagnoses separates them: 846 (with MCC), 847 (with CC), 848 (without CC/MCC). A major complication or comorbidity (MCC) places the case in the highest-weighted DRG of the family; a CC in the middle; neither in the lowest.

How many diagnosis codes group to DRG 848?

3 ICD-10-CM principal diagnosis codes group to this DRG, spanning 2 three-character categories.

What is the relative weight of DRG 848?

The FY 2026 relative weight of this DRG is 0.8494, meaning reimbursement of roughly 0.85 times the average Medicare inpatient case. Multiply by a hospital's blended base rate for the approximate payment.

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Source: CMS ICD-10 MS-DRG v43.0 Definitions Manual and the FY 2026 IPPS Final Rule (Table 5), effective October 1, 2025 through September 30, 2026. We publish the DRG assignments as CMS defines them and add the navigation, search, and code links.