MS-DRG · FY 2026 v43.0

MS-DRG 378 – Gastrointestinal Hemorrhage with CC

A Medical DRG in MDC 06 (Diseases & Disorders of the Digestive System). Inpatient cases group to DRG 378 when the ICD-10-CM principal diagnosis is one of the 44 codes listed below and a secondary diagnosis on the complication or comorbidity (CC) list is present. Its FY 2026 relative weight is 0.9807 with a geometric mean length of stay of 2.9 days.

Medical DRG – assigned by principal diagnosis✓ Official CMS v43.0 dataset
0.9807
Relative Weight
2.9
Geometric Mean LOS (days)
3.5
Arithmetic Mean LOS (days)
44
Principal Diagnosis Codes

Severity family

DRG 377with MCCWeight 1.8280 · GMLOS 4.5 daysDRG 378with CCWeight 0.9807 · GMLOS 2.9 daysDRG 379without CC/MCCWeight 0.6304 · GMLOS 2.0 days
How a case is assigned to DRG 378

The grouper first assigns the case to MDC 06 from the principal diagnosis and finds no qualifying operating-room procedure (this is a Medical DRG; ICD-10-PCS codes do not drive assignment here), then applies the severity split from secondary diagnoses: with MCC → 377; with CC → 378; without CC/MCC → 379.

ICD-10-CM

Principal Diagnosis Codes 44 codes · 10 categories

44 of 44 shown
K25 Gastric ulcer4 codes
  • K25.0 Acute gastric ulcer with hemorrhage
  • K25.2 Acute gastric ulcer with both hemorrhage and perforation
  • K25.4 Chronic or unspecified gastric ulcer with hemorrhage
  • K25.6 Chronic or unspecified gastric ulcer with both hemorrhage and perforation
K26 Duodenal ulcer4 codes
  • K26.0 Acute duodenal ulcer with hemorrhage
  • K26.2 Acute duodenal ulcer with both hemorrhage and perforation
  • K26.4 Chronic or unspecified duodenal ulcer with hemorrhage
  • K26.6 Chronic or unspecified duodenal ulcer with both hemorrhage and perforation
K27 Peptic ulcer, site unspecified4 codes
  • K27.0 Acute peptic ulcer, site unspecified, with hemorrhage
  • K27.2 Acute peptic ulcer, site unspecified, with both hemorrhage and perforation
  • K27.4 Chronic or unspecified peptic ulcer, site unspecified, with hemorrhage
  • K27.6 Chronic or unspecified peptic ulcer, site unspecified, with both hemorrhage and perforation
K28 Gastrojejunal ulcer4 codes
  • K28.0 Acute gastrojejunal ulcer with hemorrhage
  • K28.2 Acute gastrojejunal ulcer with both hemorrhage and perforation
  • K28.4 Chronic or unspecified gastrojejunal ulcer with hemorrhage
  • K28.6 Chronic or unspecified gastrojejunal ulcer with both hemorrhage and perforation
K29 Gastritis and duodenitis9 codes
  • K29.01 Acute gastritis with bleeding
  • K29.21 Alcoholic gastritis with bleeding
  • K29.31 Chronic superficial gastritis with bleeding
  • K29.41 Chronic atrophic gastritis with bleeding
  • K29.51 Unspecified chronic gastritis with bleeding
  • K29.61 Other gastritis with bleeding
  • K29.71 Gastritis, unspecified, with bleeding
  • K29.81 Duodenitis with bleeding
  • K29.91 Gastroduodenitis, unspecified, with bleeding
K31 Other diseases of stomach and duodenum2 codes
  • K31.811 Angiodysplasia of stomach and duodenum with bleeding
  • K31.82 Dieulafoy lesion (hemorrhagic) of stomach and duodenum
K55 Vascular disorders of intestine1 code
  • K55.21 Angiodysplasia of colon with hemorrhage
K57 Diverticular disease of intestine12 codes
  • K57.01 Diverticulitis of small intestine with perforation and abscess with bleeding
  • K57.11 Diverticulosis of small intestine without perforation or abscess with bleeding
  • K57.13 Diverticulitis of small intestine without perforation or abscess with bleeding
  • K57.21 Diverticulitis of large intestine with perforation and abscess with bleeding
  • K57.31 Diverticulosis of large intestine without perforation or abscess with bleeding
  • K57.33 Diverticulitis of large intestine without perforation or abscess with bleeding
  • K57.41 Diverticulitis of both small and large intestine with perforation and abscess with bleeding
  • K57.51 Diverticulosis of both small and large intestine without perforation or abscess with bleeding
  • K57.53 Diverticulitis of both small and large intestine without perforation or abscess with bleeding
  • K57.81 Diverticulitis of intestine, part unspecified, with perforation and abscess with bleeding
  • K57.91 Diverticulosis of intestine, part unspecified, without perforation or abscess with bleeding
  • K57.93 Diverticulitis of intestine, part unspecified, without perforation or abscess with bleeding
K62 Other diseases of anus and rectum1 code
  • K62.5 Hemorrhage of anus and rectum
K92 Other diseases of digestive system3 codes
  • K92.0 Hematemesis
  • K92.1 Melena
  • K92.2 Gastrointestinal hemorrhage, unspecified
ICD-10-PCS

Procedure Codes

Procedure codes do not drive assignment for this DRG. DRG 378 is a Medical DRG, assigned from the principal diagnosis above.

Frequently Asked Questions

What is MS-DRG 378?

MS-DRG 378 (Gastrointestinal Hemorrhage with CC) is a medical DRG in MDC 06 (Diseases & Disorders of the Digestive System). Its FY 2026 relative weight is 0.9807 with a geometric mean length of stay of 2.9 days.

What is the difference between DRG 377, 378, 379?

All 3 share the same base category; the severity of secondary diagnoses separates them: 377 (with MCC), 378 (with CC), 379 (without CC/MCC). A major complication or comorbidity (MCC) places the case in the highest-weighted DRG of the family; a CC in the middle; neither in the lowest.

How many diagnosis codes group to DRG 378?

44 ICD-10-CM principal diagnosis codes group to this DRG, spanning 10 three-character categories.

What is the relative weight of DRG 378?

The FY 2026 relative weight of this DRG is 0.9807, meaning reimbursement of roughly 0.98 times the average Medicare inpatient case. Multiply by a hospital's blended base rate for the approximate payment.

← PreviousDRG 377 – Gastrointestinal Hemorrhage with MCC
Source: CMS ICD-10 MS-DRG v43.0 Definitions Manual and the FY 2026 IPPS Final Rule (Table 5), effective October 1, 2025 through September 30, 2026. We publish the DRG assignments as CMS defines them and add the navigation, search, and code links.