ICD-10 Code A81.2

Progressive multifocal leukoencephalopathy

Version 2019 Billable Code
ICD-10: A81.2
Short Description:Progressive multifocal leukoencephalopathy
Long Description:Progressive multifocal leukoencephalopathy

Valid for Submission

ICD-10 A81.2 is a billable code used to specify a medical diagnosis of progressive multifocal leukoencephalopathy. The code is valid for the year 2019 for the submission of HIPAA-covered transactions.

Code Classification

  • Certain infectious and parasitic diseases (A00–B99)
    • Viral and prion infections of the central nervous system (A80-A89)
      • Atypical virus infections of central nervous system (A81)

Information for Medical Professionals

Convert A81.2 to ICD-9

The following crosswalk between ICD-10 to ICD-9 is based based on the General Equivalence Mappings (GEMS) information:

  • 046.3 - Prog multifoc leukoencep (Approximate Flag)

Synonyms

The following clinical terms are approximate synonyms:

  • Central nervous system demyelinating disease associated with AIDS
  • Cerebral degeneration due to progressive multifocal leukoencephalopathy
  • Dementia due to infectious disease
  • Dementia with progressive multifocal leukoencephalopathy
  • Demyelinating disease of central nervous system co-occurrent with human immunodeficiency virus infection
  • Disease due to JC polyomavirus
  • Disease due to JC polyomavirus
  • Disease due to JC polyomavirus
  • Encephalopathy associated with AIDS
  • Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation
  • Progressive multifocal leukoencephalopathy
  • Progressive multifocal leukoencephalopathy
  • Progressive multifocal leukoencephalopathy
  • Progressive multifocal leukoencephalopathy associated with AIDS
  • Progressive multifocal leukoencephalopathy co-occurrent with human immunodeficiency virus infection
  • White matter disease
  • White matter disease
  • White matter disease
  • White matter disorder caused by infection

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code A81.2 are found in the index:


Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references for the code A81.2 are found in the tabular index:

  • Inclusion Terms:
    • Multifocal leukoencephalopathy NOS

Information for Patients


Degenerative Nerve Diseases

Also called: Neurodegenerative diseases

Degenerative nerve diseases affect many of your body's activities, such as balance, movement, talking, breathing, and heart function. Many of these diseases are genetic. Sometimes the cause is a medical condition such as alcoholism, a tumor, or a stroke. Other causes may include toxins, chemicals, and viruses. Sometimes the cause is not known.

Degenerative nerve diseases include

  • Alzheimer's disease
  • Amyotrophic lateral sclerosis
  • Friedreich's ataxia
  • Huntington's disease
  • Lewy body disease
  • Parkinson's disease
  • Spinal muscular atrophy

Degenerative nerve diseases can be serious or life-threatening. It depends on the type. Most of them have no cure. Treatments may help improve symptoms, relieve pain, and increase mobility.

  • Multiple system atrophy (Medical Encyclopedia)
  • Progressive multifocal leukoencephalopathy (Medical Encyclopedia)

[Learn More]

Encephalitis

Encephalitis is an inflammation of the brain. Usually the cause is a viral infection, but bacteria can also cause it. It can be mild or severe. Most cases are mild. You may have flu-like symptoms. With a mild case, you may just need rest, plenty of fluids, and a pain reliever.

Severe cases need immediate treatment. Symptoms of severe cases include

  • Severe headache
  • Sudden fever
  • Drowsiness
  • Vomiting
  • Confusion
  • Seizures

In babies, additional symptoms may include constant crying, poor feeding, body stiffness, and bulging in the soft spots of the skull.

Severe cases may require a stay in the hospital. Treatments include oral and intravenous (IV) medicines to reduce inflammation and treat infection. Patients with breathing difficulties may need artificial respiration. Some people may need physical, speech, and occupational therapy once the illness is under control.

NIH: National Institute of Neurological Disorders and Stroke

  • Cerebral spinal fluid (CSF) collection (Medical Encyclopedia)
  • CSF analysis (Medical Encyclopedia)
  • Encephalitis (Medical Encyclopedia)
  • Japanese Encephalitis Vaccine: What You Need to Know (Centers for Disease Control and Prevention)
  • Subacute sclerosing panencephalitis (Medical Encyclopedia)

[Learn More]

Viral Infections

Viruses are very tiny germs. They are made of genetic material inside of a protein coating. Viruses cause familiar infectious diseases such as the common cold, flu and warts. They also cause severe illnesses such as HIV/AIDS, smallpox, and Ebola.

Viruses are like hijackers. They invade living, normal cells and use those cells to multiply and produce other viruses like themselves. This can kill, damage, or change the cells and make you sick. Different viruses attack certain cells in your body such as your liver, respiratory system, or blood.

When you get a virus, you may not always get sick from it. Your immune system may be able to fight it off.

For most viral infections, treatments can only help with symptoms while you wait for your immune system to fight off the virus. Antibiotics do not work for viral infections. There are antiviral medicines to treat some viral infections. Vaccines can help prevent you from getting many viral diseases.

  • ECHO virus (Medical Encyclopedia)
  • Enterovirus D68 (Medical Encyclopedia)
  • Hand-foot-mouth disease (Medical Encyclopedia)
  • Herpangina (Medical Encyclopedia)
  • Molluscum contagiosum (Medical Encyclopedia)
  • Parainfluenza (Medical Encyclopedia)
  • Roseola (Medical Encyclopedia)
  • Zika virus disease (Medical Encyclopedia)

[Learn More]

ICD-10 Footnotes

General Equivalence Map Definitions
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Approximate Flag - The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
  • No Map Flag - The no map flag indicates that a code in the source system is not linked to any code in the target system.
  • Combination Flag - The combination flag indicates that more than one code in the target system is required to satisfy the full equivalent meaning of a code in the source system.

Index of Diseases and Injuries Definitions

  • And - The word "and" should be interpreted to mean either "and" or "or" when it appears in a title.
  • Code also note - A "code also" note instructs that two codes may be required to fully describe a condition, but this note does not provide sequencing direction.
  • Code first - Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
  • Type 1 Excludes Notes - A type 1 Excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • Type 2 Excludes Notes - A type 2 Excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
  • Includes Notes - This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
  • Inclusion terms - List of terms is included under some codes. These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • NEC "Not elsewhere classifiable" - This abbreviation in the Alphabetic Index represents "other specified". When a specific code is not available for a condition, the Alphabetic Index directs the coder to the "other specified” code in the Tabular List.
  • NOS "Not otherwise specified" - This abbreviation is the equivalent of unspecified.
  • See - The "see" instruction following a main term in the Alphabetic Index indicates that another term should be referenced. It is necessary to go to the main term referenced with the "see" note to locate the correct code.
  • See Also - A "see also" instruction following a main term in the Alphabetic Index instructs that there is another main term that may also be referenced that may provide additional Alphabetic Index entries that may be useful. It is not necessary to follow the "see also" note when the original main term provides the necessary code.
  • 7th Characters - Certain ICD-10-CM categories have applicable 7th characters. The applicable 7th character is required for all codes within the category, or as the notes in the Tabular List instruct. The 7th character must always be the 7th character in the data field. If a code that requires a 7th character is not 6 characters, a placeholder X must be used to fill in the empty characters.
  • With - The word "with" should be interpreted to mean "associated with" or "due to" when it appears in a code title, the Alphabetic Index, or an instructional note in the Tabular List. The word "with" in the Alphabetic Index is sequenced immediately following the main term, not in alphabetical order.