ICD-10-CM Code B39.4

Histoplasmosis capsulati, unspecified

Version 2021 Billable Code

Valid for Submission

B39.4 is a billable code used to specify a medical diagnosis of histoplasmosis capsulati, unspecified. The code is valid for the fiscal year 2021 for the submission of HIPAA-covered transactions. The ICD-10-CM code B39.4 might also be used to specify conditions or terms like classical histoplasmosis intestinal ulceration, classical histoplasmosis mediastinal granuloma, classical histoplasmosis mucosal ulceration, classical histoplasmosis mucosal ulceration, classical histoplasmosis nasal ulceration, classical histoplasmosis oral ulceration, etc

Short Description:Histoplasmosis capsulati, unspecified
Long Description:Histoplasmosis capsulati, unspecified

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code B39.4:

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • American histoplasmosis

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code B39.4 are found in the index:


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Classical histoplasmosis intestinal ulceration
  • Classical histoplasmosis mediastinal granuloma
  • Classical histoplasmosis mucosal ulceration
  • Classical histoplasmosis mucosal ulceration
  • Classical histoplasmosis nasal ulceration
  • Classical histoplasmosis oral ulceration
  • Classical histoplasmosis penile ulceration
  • Cutaneous histoplasmosis
  • Fungal meningitis
  • Histoplasma capsulatum with endocarditis
  • Histoplasma capsulatum with pericarditis
  • Histoplasma capsulatum with retinitis
  • Histoplasma infection of central nervous system
  • Histoplasmosis liver
  • Histoplasmosis with pericarditis
  • Histoplasmosis with retinitis
  • Infection by Histoplasma capsulatum
  • Meningitis caused by Histoplasma capsulatum
  • Meningitis caused by Histoplasmosis
  • Mycotic endocarditis
  • Oral mucosal fungal disease
  • Ulcer of nose

Diagnostic Related Groups

The ICD-10 code B39.4 is grouped in the following groups for version MS-DRG V38.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2020 through 09/30/2021.


Convert B39.4 to ICD-9

  • 115.00 - Histoplasma capsulat NOS (Approximate Flag)

Code Classification

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

Information for Patients


Histoplasmosis is a disease caused by a fungus (or mold) called Histoplasma. The fungus is common in the eastern and central United States. It grows in soil and material contaminated with bat or bird droppings. You get infected by breathing the fungal spores. You cannot get the infection from someone else.

Histoplasmosis is often mild, with no symptoms. If you do get sick, it usually affects your lungs. Symptoms include feeling ill, fever, chest pains, and a dry cough. In severe cases, histoplasmosis spreads to other organs. This is called disseminated disease. It is more common in infants, young children, seniors, and people with immune system problems.

Your doctor might do a variety of tests to make the diagnosis, including a chest x-ray, CT scan of the lungs, or examining blood, urine, or tissues for signs of the fungus. Mild cases usually get better without treatment. Treatment of severe or chronic cases is with antifungal drugs.

Centers for Disease Control and Prevention

  • Histoplasma complement fixation (Medical Encyclopedia)
  • Histoplasma skin test (Medical Encyclopedia)
  • Histoplasmosis (Medical Encyclopedia)
  • Histoplasmosis - acute (primary) pulmonary (Medical Encyclopedia)

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