ICD-9 Code 995.22

Unspecified adverse effect of anesthesia

Not Valid for Submission

995.22 is a legacy non-billable code used to specify a medical diagnosis of unspecified adverse effect of anesthesia. This code was replaced on September 30, 2015 by its ICD-10 equivalent.

ICD-9: 995.22
Short Description:Adv eff anesthesia NOS
Long Description:Unspecified adverse effect of anesthesia

Convert 995.22 to ICD-10

The following crosswalk between ICD-9 to ICD-10 is based based on the General Equivalence Mappings (GEMS) information:

  • T41.0X5A - Adverse effect of inhaled anesthetics, initial encounter
  • T41.1X5A - Adverse effect of intravenous anesthetics, initial encounter
  • T41.205A - Adverse effect of unsp general anesthetics, init encntr
  • T41.295A - Adverse effect of other general anesthetics, init encntr
  • T41.3X5A - Adverse effect of local anesthetics, initial encounter
  • T41.45XA - Adverse effect of unspecified anesthetic, initial encounter
  • T88.59XA - Other complications of anesthesia, initial encounter

Code Classification

  • Injury and poisoning (800–999)
    • Other and unspecified effects of external causes (990-995)
      • 995 Certain adverse effects, not elsewhere classified

Information for Medical Professionals


  • Adverse reaction to cyclopropane
  • Adverse reaction to nitrous oxide
  • Adverse reaction to peripheral nerve- and plexus-blocking anesthetics
  • Adverse reaction to spinal anesthetic
  • Adverse reaction to surface and infiltration anesthetic
  • Adverse reaction to tetracaine
  • Anesthetics adverse reaction
  • Anesthetics and medical gases adverse reaction
  • Bupivacaine adverse reaction
  • Cinchocaine adverse reaction
  • Cocaine adverse reaction
  • Delayed recovery from anesthesia
  • Desflurane adverse reaction
  • Dimethyl-ether propane adverse reaction
  • Enflurane adverse reaction
  • Ether, anesthetic adverse reaction
  • Ether, anesthetic allergy
  • Etomidate adverse reaction
  • Etomidate allergy
  • Excessive spread of local anesthetic
  • Failed epidural anesthesia
  • Failed neuraxial nerve block
  • Failed spinal anesthesia
  • General anesthetic drug adverse reaction
  • Glucagon adverse reaction
  • Halothane adverse reaction
  • Halothane allergy
  • Inappropriate dilution of inhaled anesthetic agent
  • Incomplete reversal of neuromuscular block
  • Inhalational anesthetics adverse reaction
  • Intravenous anesthetics adverse reaction
  • Intravenous anesthetics allergy
  • Isoflurane adverse reaction
  • Isoflurane allergy
  • Ketamine allergy
  • Lignocaine adverse reaction
  • Local anesthetic block inadequate
  • Local anesthetic drug adverse reaction
  • Methohexitone adverse reaction
  • Neuromuscular block problem
  • Oxybuprocaine adverse reaction
  • Postanesthesia apnea
  • Prilocaine adverse reaction
  • Problem encountered during administration of local anesthetic
  • Procaine adverse reaction
  • Prolonged neuromuscular block
  • Propofol adverse reaction
  • Regional blockade - excessive cephalad spread of local anesthesia
  • Thiopentone adverse reaction
  • Total spinal nerve blockade following local anesthetic injection
  • Trichloroethylene adverse reaction

Index to Diseases and Injuries

References found for the code 995.22 in the Index of Diseases and Injuries:

Information for Patients


If you are having surgery, your doctor will give you medicine called an anesthetic. Anesthetics reduce or prevent pain. There are three main types:

  • Local - numbs one small area of the body. You stay awake and alert.
  • Regional - blocks pain in an area of the body, such an arm or leg. A common type is epidural anesthesia, which is often used during childbirth.
  • General - makes you unconscious. You do not feel any pain, and you do not remember the procedure afterwards.

You may also get a mild sedative to relax you. You stay awake but may not remember the procedure afterwards. Sedation can be used with or without anesthesia.

The type of anesthesia or sedation you get depends on many factors. They include the procedure you are having and your current health.

  • Conscious sedation for surgical procedures
  • Epidural block
  • General anesthesia
  • Spinal and epidural anesthesia

[Read More]

ICD-9 Footnotes

General Equivalence Map Definitions
The ICD-9 and ICD-10 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Approximate Flag - The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
  • No Map Flag - The no map flag indicates that a code in the source system is not linked to any code in the target system.
  • Combination Flag - The combination flag indicates that more than one code in the target system is required to satisfy the full equivalent meaning of a code in the source system.

Index of Diseases and Injuries Definitions

  • And - The word "and" should be interpreted to mean either "and" or "or" when it appears in a title.
  • Code also note - A "code also" note instructs that two codes may be required to fully describe a condition, but this note does not provide sequencing direction.
  • Code first - Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
  • Type 1 Excludes Notes - A type 1 Excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • Type 2 Excludes Notes - A type 2 Excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
  • Includes Notes - This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
  • Inclusion terms - List of terms is included under some codes. These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • NEC "Not elsewhere classifiable" - This abbreviation in the Alphabetic Index represents "other specified". When a specific code is not available for a condition, the Alphabetic Index directs the coder to the "other specified” code in the Tabular List.
  • NOS "Not otherwise specified" - This abbreviation is the equivalent of unspecified.
  • See - The "see" instruction following a main term in the Alphabetic Index indicates that another term should be referenced. It is necessary to go to the main term referenced with the "see" note to locate the correct code.
  • See Also - A "see also" instruction following a main term in the Alphabetic Index instructs that there is another main term that may also be referenced that may provide additional Alphabetic Index entries that may be useful. It is not necessary to follow the "see also" note when the original main term provides the necessary code.
  • 7th Characters - Certain ICD-10-CM categories have applicable 7th characters. The applicable 7th character is required for all codes within the category, or as the notes in the Tabular List instruct. The 7th character must always be the 7th character in the data field. If a code that requires a 7th character is not 6 characters, a placeholder X must be used to fill in the empty characters.
  • With - The word "with" should be interpreted to mean "associated with" or "due to" when it appears in a code title, the Alphabetic Index, or an instructional note in the Tabular List. The word "with" in the Alphabetic Index is sequenced immediately following the main term, not in alphabetical order.