ICD-9 Code 655.21

Hereditary disease in family possibly affecting fetus, affecting management of mother, delivered, with or without mention of antepartum condition

Not Valid for Submission

655.21 is a legacy non-billable code used to specify a medical diagnosis of hereditary disease in family possibly affecting fetus, affecting management of mother, delivered, with or without mention of antepartum condition. This code was replaced on September 30, 2015 by its ICD-10 equivalent.

ICD-9: 655.21
Short Description:Famil heredit dis-deliv
Long Description:Hereditary disease in family possibly affecting fetus, affecting management of mother, delivered, with or without mention of antepartum condition

Convert 655.21 to ICD-10

The following crosswalk between ICD-9 to ICD-10 is based based on the General Equivalence Mappings (GEMS) information:

  • O35.2XX0 - Maternal care for hereditary disease in fetus, unsp

Code Classification

  • Complications of pregnancy, childbirth, and the puerperium (630–679)
    • Normal delivery, and other indications for care in pregnancy, labor, and delivery (650-659)
      • 655 Known or suspected fetal abnormality affecting management of mother

Information for Medical Professionals

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-9 Code Edits are applicable to this code:

Information for Patients


Childbirth Problems

While childbirth usually goes well, complications can happen. They can cause a risk to the mother, baby, or both. Possible complications include

  • Preterm (premature) labor, when labor starts before 37 completed weeks of pregnancy
  • Problems with the umbilical cord
  • Problems with the position of the baby, such as breech, in which the baby is going to come out feet first
  • Birth injuries

For some of these problems, the baby may need to be delivered surgically by a Cesarean section.

  • Assisted delivery with forceps
  • Brachial plexus injury in newborns
  • Breech birth
  • Caput succedaneum
  • Fractured clavicle in the newborn
  • Meconium aspiration syndrome
  • Placenta previa
  • Premature rupture of membranes
  • Sheehan syndrome
  • Vacuum-assisted delivery
  • When you pass your due date

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Fetal Health and Development

A normal pregnancy lasts nine months. Each three-month period of pregnancy is called a trimester. During each trimester, the fetus grows and develops. There are specific prenatal tests to monitor both the mother's health and fetal health during each trimester.

With modern technology, health professionals can

  • Detect birth defects
  • Identify problems that may affect childbirth
  • Correct some kinds of fetal problems before the baby is born
  • Developmental disorders of the female reproductive tract
  • Fetal development
  • Intrauterine growth restriction

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Genetic Disorders

Genes are the building blocks of heredity. They are passed from parent to child. They hold DNA, the instructions for making proteins. Proteins do most of the work in cells. They move molecules from one place to another, build structures, break down toxins, and do many other maintenance jobs.

Sometimes there is a mutation, a change in a gene or genes. The mutation changes the gene's instructions for making a protein, so the protein does not work properly or is missing entirely. This can cause a medical condition called a genetic disorder.

You can inherit a gene mutation from one or both parents. A mutation can also happen during your lifetime.

There are three types of genetic disorders:

  • Single-gene disorders, where a mutation affects one gene. Sickle cell anemia is an example.
  • Chromosomal disorders, where chromosomes (or parts of chromosomes) are missing or changed. Chromosomes are the structures that hold our genes. Down syndrome is a chromosomal disorder.
  • Complex disorders, where there are mutations in two or more genes. Often your lifestyle and environment also play a role. Colon cancer is an example.

Genetic tests on blood and other tissue can identify genetic disorders.

NIH: National Library of Medicine

  • Genetics

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ICD-9 Footnotes

General Equivalence Map Definitions
The ICD-9 and ICD-10 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Approximate Flag - The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
  • No Map Flag - The no map flag indicates that a code in the source system is not linked to any code in the target system.
  • Combination Flag - The combination flag indicates that more than one code in the target system is required to satisfy the full equivalent meaning of a code in the source system.