ICD-9 Diagnosis Code 281.3

Megaloblastic anemia NEC

Diagnosis Code 281.3

ICD-9: 281.3
Short Description: Megaloblastic anemia NEC
Long Description: Other specified megaloblastic anemias not elsewhere classified
This is the 2014 version of the ICD-9-CM diagnosis code 281.3

Code Classification
  • Diseases of the blood and blood-forming organs (280–289)
    • Diseases of the blood and blood-forming organs (280-289)
      • 281 Other deficiency anemias

Information for Medical Professionals

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The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.
  • D53.1 - Other megaloblastic anemias, not elsewhere classified

  • Acute megaloblastic anemia due to dialysis
  • Acute megaloblastic anemia due to nitrous oxide
  • Acute megaloblastic anemia due to severe illness
  • Acute megaloblastic anemia secondary to total parenteral nutrition
  • Combined B12 and folate deficiency anemia
  • Familial megaloblastic anemia
  • Juvenile type megaloblastic anemia
  • Megaloblastic anemia due to alcoholism
  • Megaloblastic anemia due to blind loop syndrome
  • Megaloblastic anemia due to chronic hemolytic anemia
  • Megaloblastic anemia due to congenital deficiency of intrinsic factor
  • Megaloblastic anemia due to decreased intake of vitamin B>12<
  • Megaloblastic anemia due to disease of small intestine
  • Megaloblastic anemia due to drugs
  • Megaloblastic anemia due to error of cobalamin metabolism
  • Megaloblastic anemia due to error of folate metabolism
  • Megaloblastic anemia due to exfoliative dermatitis
  • Megaloblastic anemia due to gastrectomy
  • Megaloblastic anemia due to hemodialysis
  • Megaloblastic anemia due to inborn errors of metabolism
  • Megaloblastic anemia due to increased requirements
  • Megaloblastic anemia due to nontropical sprue
  • Megaloblastic anemia due to pancreatic insufficiency
  • Megaloblastic anemia due to tropical sprue
  • Megaloblastic anemia due to vitamin B>12< deficiency
  • Megaloblastic anemia due to Zollinger-Ellison syndrome
  • Refractory megaloblastic anemia
  • Thiamine-responsive megaloblastic anemia

Index of Diseases and Injuries
References found for the code 281.3 in the Index of Diseases and Injuries:

Information for Patients


Also called: Iron poor blood

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Anemia has three main causes: blood loss, lack of red blood cell production, and high rates of red blood cell destruction.

Conditions that may lead to anemia include

  • Heavy periods
  • Pregnancy
  • Ulcers
  • Colon polyps or colon cancer
  • Inherited disorders
  • A diet that does not have enough iron, folic acid or vitamin B12
  • Blood disorders such as sickle cell anemia and thalassemia, or cancer
  • Aplastic anemia, a condition that can be inherited or acquired
  • G6PD deficiency, a metabolic disorder

Anemia can make you feel tired, cold, dizzy, and irritable. You may be short of breath or have a headache.

Your doctor will diagnose anemia with a physical exam and blood tests. Treatment depends on the kind of anemia you have.

NIH: National Heart, Lung, and Blood Institute

  • Anemia
  • Anemia - B12 deficiency
  • Anemia caused by low iron -- infants and toddlers
  • Anemia of chronic disease
  • Anemia of Inflammation and Chronic Disease - NIH
  • Antiparietal cell antibody test
  • Congenital spherocytic anemia
  • Ferritin blood test
  • Folate-deficiency anemia
  • Hemoglobin electrophoresis
  • Hemolytic anemia
  • Hemolytic anemia caused by chemicals and toxins
  • Immune hemolytic anemia
  • Iron deficiency anemia
  • Managing Chemotherapy Side Effects: Anemia - NIH - Easy-to-Read (National Cancer Institute)
  • Pernicious anemia
  • Serum free hemoglobin test
  • Serum iron test
  • Total iron binding capacity
  • Vitamin B12 level

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