2024 ICD-10-CM Diagnosis Code Z85.6

Personal history of leukemia

ICD-10-CM Code:
Z85.6
ICD-10 Code for:
Personal history of leukemia
Is Billable?
Yes - Valid for Submission
Code Navigator:

Code Classification

  • Factors influencing health status and contact with health services
    (Z00–Z99)
    • Persons with potential health hazards related to family and personal history and certain conditions influencing health status
      (Z77-Z99)
      • Personal history of malignant neoplasm
        (Z85)

Z85.6 is a billable diagnosis code used to specify a medical diagnosis of personal history of leukemia. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.

This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • History of acute leukemia
  • History of acute lymphoid leukemia
  • History of acute myeloid leukemia
  • History of chronic lymphocytic leukemia
  • History of leukemia
  • History of lymphoid leukemia
  • History of monocytic leukemia
  • History of myeloid leukemia

Clinical Classification

Clinical Information

  • Personal History of Leukemia

    an individual history of leukemia.

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

  • Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)

Z85.6 is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.

CMS POA Indicator Options and Definitions

POA IndicatorReason for CodeCMS will pay the CC/MCC DRG?
YDiagnosis was present at time of inpatient admission.YES
NDiagnosis was not present at time of inpatient admission.NO
UDocumentation insufficient to determine if the condition was present at the time of inpatient admission.NO
WClinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.YES
1Unreported/Not used - Exempt from POA reporting. NO

Convert Z85.6 to ICD-9-CM

  • ICD-9-CM Code: V10.60 - Hx of leukemia NOS
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education


Leukemia

What is leukemia?

Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. Each type of cell has a different job:

  • White blood cells help your body fight infection
  • Red blood cells deliver oxygen from your lungs to your tissues and organs
  • Platelets help form clots to stop bleeding

When you have leukemia, your bone marrow makes large numbers of abnormal cells. This problem most often happens with white blood cells. These abnormal cells build up in your bone marrow and blood. They crowd out the healthy blood cells and make it hard for your cells and blood to do their work.

What are the types of leukemia?

There are different types of leukemia. Which type of leukemia you have depends on the type of blood cell that becomes cancer and whether it grows quickly or slowly.

The type of blood cell could be:

  • Lymphocytes, a type of white blood cell
  • Myeloid cells, immature cells that become white blood cells, red blood cells, or platelets

The different types can grow quickly or slowly:

  • Acute leukemia is fast growing. It usually gets worse quickly if it's not treated.
  • Chronic leukemia is slow growing. It usually gets worse over a longer period of time.

The main types of leukemia are:

  • Acute lymphocytic leukemia (ALL), which is the most common type of cancer in children. It can also affect adults.
  • Acute myeloid leukemia (AML), which is more common in older adults but can also affect children
  • Chronic lymphocytic leukemia (CLL), which is one of the most common types of leukemia in adults. It often occurs during or after middle age.
  • Chronic myeloid leukemia (CML), which usually occurs in adults during or after middle age

What causes leukemia?

Leukemia happens when there are changes in the genetic material (DNA) in bone marrow cells. The cause of these genetic changes is unknown.

Who is at risk for leukemia?

For the specific types, there are different factors which can raise your risk of getting that type. Overall, your risk of leukemia goes up as you age. It is most common over age 60.

What are the symptoms of leukemia?

Some of the symptoms of leukemia may include:

  • Feeling tired
  • Fever or night sweats
  • Easy bruising or bleeding
  • Weight loss or loss of appetite
  • Petechiae, which are tiny red dots under the skin. They are caused by bleeding.

Other leukemia symptoms can be different from type to type. Chromic leukemia may not cause symptoms at first.

How is leukemia diagnosed?

Your health care provider may use many tools to diagnose leukemia:

  • A physical exam
  • A medical history
  • Blood tests, such as a complete blood count (CBC)
  • Bone marrow tests. There are two main types - bone marrow aspiration and bone marrow biopsy. Both tests involve removing a sample of bone marrow and bone. The samples are sent to a lab for testing.
  • Genetic tests to look for gene and chromosome changes

Once the provider makes a diagnosis, there may be additional tests to see whether the cancer has spread. These include imaging tests and a lumbar puncture, which is a procedure to collect and test cerebrospinal fluid (CSF).

What are the treatments for leukemia?

The treatments for leukemia depend on which type you have, how severe the leukemia is, your age, your overall health, and other factors. Some possible treatments might include:

  • Chemotherapy
  • Radiation therapy
  • Chemotherapy with stem cell transplant
  • Targeted therapy, which uses drugs or other substances that attack specific cancer cells with less harm to normal cells

NIH: National Cancer Institute


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.