ICD-10 Diagnosis Code Z51.1

Encounter for antineoplastic chemotherapy and immunotherapy

Diagnosis Code Z51.1

ICD-10: Z51.1
Short Description: Encounter for antineoplastic chemotherapy and immunotherapy
Long Description: Encounter for antineoplastic chemotherapy and immunotherapy
This is the 2018 version of the ICD-10-CM diagnosis code Z51.1

Not Valid for Submission
The code Z51.1 is a "header" and not valid for submission for HIPAA-covered transactions.

Code Classification
  • Factors influencing health status and contact with health services (Z00–Z99)
    • Encounters for other specific health care (Z40-Z53)
      • Encounter for other aftercare and medical care (Z51)

Information for Medical Professionals

Information for Patients


Cancer Chemotherapy

Normally, your cells grow and die in a controlled way. Cancer cells keep growing without control. Chemotherapy is drug therapy for cancer. It works by killing the cancer cells, stopping them from spreading, or slowing their growth. However, it can also harm healthy cells, which causes side effects.

You may have a lot of side effects, some, or none at all. It depends on the type and amount of chemotherapy you get and how your body reacts. Some common side effects are fatigue, nausea, vomiting, pain, and hair loss. There are ways to prevent or control some side effects. Talk with your health care provider about how to manage them. Healthy cells usually recover after chemotherapy is over, so most side effects gradually go away.

Your treatment plan will depend on the cancer type, the chemotherapy drugs used, the treatment goal, and how your body responds. Chemotherapy may be given alone or with other treatments. You may get treatment every day, every week, or every month. You may have breaks between treatments so that your body has a chance to build new healthy cells. You might take the drugs by mouth, in a shot, as a cream, or intravenously (by IV).

NIH: National Cancer Institute

  • After chemotherapy - discharge (Medical Encyclopedia)
  • Central venous catheter - dressing change (Medical Encyclopedia)
  • Central venous catheter - flushing (Medical Encyclopedia)
  • Central venous catheters - ports (Medical Encyclopedia)
  • Chemotherapy and Your Mouth - NIH (National Institute of Dental and Craniofacial Research)
  • Low white blood cell count and cancer (Medical Encyclopedia)
  • Managing Chemotherapy Side Effects: Anemia - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Appetite Changes - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Bleeding Problems - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Constipation - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Diarrhea - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Fatigue (Feeling Weak and Very Tired) - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Hair Loss (Alopecia) - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Infection - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Memory Changes - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Mouth and Throat Changes - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Nausea and Vomiting - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Nerve Changes - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Pain - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Sexual and Fertility Changes in Men - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Sexual and Fertility Changes in Women - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Skin and Nail Changes - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Swelling (Fluid Retention) - NIH - Easy-to-Read (National Cancer Institute)
  • Managing Chemotherapy Side Effects: Urination Changes - NIH - Easy-to-Read (National Cancer Institute)
  • Oral mucositis (Medical Encyclopedia)
  • Types of chemotherapy (Medical Encyclopedia)
  • Understanding Chemotherapy - NIH - Easy-to-Read (National Cancer Institute)


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Cancer Immunotherapy

Immunotherapy is a cancer treatment that helps your immune system fight cancer. It is a type of biological therapy. Biological therapy uses substances that are made from living organisms, or versions of these substances that are made in a lab.

Doctors don't yet use immunotherapy as often as other cancer treatments, such as surgery, chemotherapy, and radiation therapy. But they do use immunotherapy for some types of cancer, and researchers are doing clinical trials to see whether it also works for other types.

When you have cancer, some of your cells begin to multiply without stopping. They spread into the surrounding tissues. One reason that the cancer cells can keep growing and spreading is that they are able to hide from your immune system. Some immunotherapies can "mark" your cancer cells. This makes it easier for your immune system to find and destroy the cells. It is a type of targeted therapy, a treatment that specifically targets cancer cells. Other types of immunotherapies work by boosting your immune system to work better against cancer.

You could get immunotherapy intravenously (by IV), in pills or capsules, or in a cream for your skin. For bladder cancer, they might place it directly into your bladder. You may have treatment every day, week, or month. Some immunotherapies are given in cycles. It depends on your type of cancer, how advanced it is, the type of immunotherapy you get, and how well it is working.

You may have side effects. The most common side effects are skin reactions at the needle site, if you get it by IV. Other side effects may include flu-like symptoms, or rarely, severe reactions.

NIH: National Cancer Institute

  • Immunotherapy for cancer (Medical Encyclopedia)


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