2024 ICD-10-CM Diagnosis Code T50.2X1S

Poisoning by carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics, accidental (unintentional), sequela

ICD-10-CM Code:
T50.2X1S
ICD-10 Code for:
Poisn by crbnc-anhydr inhibtr, benzo/oth diuretc, acc, sqla
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
        (T50)

T50.2X1S is a billable diagnosis code used to specify a medical diagnosis of poisoning by carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics, accidental (unintentional), sequela. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.

T50.2X1S is a sequela code, includes a 7th character and should be used for complications that arise as a direct result of a condition like poisoning by carbonic-anhydrase inhibitors benzothiadiazides and other diuretics accidental (unintentional). According to ICD-10-CM Guidelines a "sequela" code should be used for chronic or residual conditions that are complications of an initial acute disease, illness or injury. The most common sequela is pain. Usually, two diagnosis codes are needed when reporting sequela. The first code describes the nature of the sequela while the second code describes the sequela or late effect.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Accidental acetazolamide overdose
  • Accidental acetazolamide poisoning
  • Accidental bendroflumethiazide overdose
  • Accidental bendroflumethiazide poisoning
  • Accidental chlorothiazide overdose
  • Accidental chlorothiazide poisoning
  • Accidental mersalyl overdose
  • Accidental osmotic diuretic overdose
  • Accidental potassium sparing diuretic overdose
  • Acetazolamide overdose
  • Bendroflumethiazide overdose
  • Bendroflumethiazide poisoning
  • Carbonic acid anhydrase inhibitor overdose
  • Chlormerodrin poisoning
  • Chlorothiazide overdose
  • Diuretic overdose
  • Mercaptomerin poisoning
  • Mercurial diuretic overdose
  • Mersalyl overdose
  • Mersalyl poisoning
  • Osmotic diuretic overdose
  • Poisoning by acetazolamide
  • Poisoning by carbonic acid anhydrase inhibitor
  • Poisoning by chlorothiazide
  • Poisoning caused by benzothiadiazine
  • Potassium sparing diuretic overdose
  • Thiazide diuretic overdose
  • Thiazide diuretic poisoning
  • Xanthine and/or xanthine derivative overdose

Clinical Classification

Clinical Information

  • Acetazolamide

    one of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. it is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. however, its usefulness is transient often because of rapid development of tolerance. its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (from smith and reynard, textbook of pharmacology, 1991, p337)
  • Amiloride

    a pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. this inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. negative potential reduces secretion of potassium and hydrogen ions. amiloride is used in conjunction with diuretics to spare potassium loss. (from gilman et al., goodman and gilman's the pharmacological basis of therapeutics, 9th ed, p705)
  • Bendroflumethiazide

    a thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. it has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (from martindale, the extra pharmacopoeia, 30th ed, p810)
  • Chlormerodrin

    a mercurial compound that has been used as a diuretic but is now superseded by more potent and less toxic drugs. the radiolabeled form has been used as a diagnostic and research tool.
  • Chlorothiazide

    a thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (from martindale, the extra pharmacopoeia, 30th ed, p812)
  • Chlorthalidone

    a benzenesulfonamide-phthalimidine that tautomerizes to a benzophenones form. it is considered a thiazide-like diuretic.
  • Clopamide

    a sulfamoylbenzamide piperidine. it is considered a thiazide-like diuretic.
  • Cyclopenthiazide

    thiazide diuretic also used as an antihypertensive agent.
  • Dichlorphenamide

    a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
  • Ethoxzolamide

    a carbonic anhydrase inhibitor used as diuretic and in glaucoma. it may cause hypokalemia.
  • Hydrochlorothiazide

    a thiazide diuretic often considered the prototypical member of this class. it reduces the reabsorption of electrolytes from the renal tubules. this results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. it is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
  • Hydroflumethiazide

    a thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (from martindale, the extra pharmacopoeia, 30th ed, p822)
  • Mefruside

    a benzene-sulfonamide-furan. it is used as a diuretic that affects the concentrating ability of the kidney, increases sodium chloride excretion, but may not spare potassium. it inhibits carbonic anhydrases and may increase the blood uric acid level.
  • Mersalyl

    a toxic thiol mercury salt formerly used as a diuretic. it inhibits various biochemical functions, especially in mitochondria, and is used to study those functions.
  • Methazolamide

    a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
  • Methyclothiazide

    a thiazide diuretic with properties similar to those of hydrochlorothiazide. (from martindale, the extra pharmacopoeia, 30th ed, p825)
  • Metolazone

    a quinazoline-sulfonamide derived diuretic that functions by inhibiting sodium chloride symporters.
  • Polythiazide

    a thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (from martindale, the extra pharmacopoeia, 30th ed, p826)
  • Triamterene

    a pteridinetriamine compound that inhibits sodium reabsorption through sodium channels in renal epithelial cells.
  • Trichlormethiazide

    a thiazide diuretic with properties similar to those of hydrochlorothiazide. (from martindale, the extra pharmacopoeia, 30th ed, p830)
  • Fosfomycin

    an antibiotic produced by streptomyces fradiae.
  • Tromethamine

    an organic amine proton acceptor. it is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (from merck, 11th ed; martindale, the extra pharmacopoeia, 30th ed, p1424)
  • Xipamide

    a sulfamoylbenzamide analog of clopamide. it is diuretic and saluretic with antihypertensive activity. it is bound to plasma proteins, thus has a delayed onset and prolonged action.

Coding Guidelines

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Present on Admission (POA)

T50.2X1S is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.

CMS POA Indicator Options and Definitions

POA IndicatorReason for CodeCMS will pay the CC/MCC DRG?
YDiagnosis was present at time of inpatient admission.YES
NDiagnosis was not present at time of inpatient admission.NO
UDocumentation insufficient to determine if the condition was present at the time of inpatient admission.NO
WClinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.YES
1Unreported/Not used - Exempt from POA reporting. NO

Convert T50.2X1S to ICD-9-CM

  • ICD-9-CM Code: 909.0 - Late eff drug poisoning
    Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment.
  • ICD-9-CM Code: E929.2 - Late eff acc poisoning
    Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment.

Table of Drugs and Chemicals

The parent code T50.2X1 of the current diagnosis code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AcetazolamideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
AltizideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
AmilorideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
AminometradineT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
AmisometradineT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
AnhydronT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
BendrofluazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
BendroflumethiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
BenzothiadiazidesT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
BenzthiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Benzylhydrochlorthia-zideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
ButizideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
CardraseT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
ChlorazanilT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
ChlormerodrinT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
ChlorothiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
ChlortalidoneT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
ChlorthalidoneT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
ClofenamideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
ClopamideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
ClorexoloneT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
CyclopenthiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
CyclothiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
DiamoxT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
DichlorphenamideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
DiclofenamideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Dihydroxypropyl theophyllineT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
DiphyllineT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
DiprophyllineT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
DisulfamideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
DiucardinT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
DiupresT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Diuretic NECT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Diuretic NEC
  »benzothiadiazine
T50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Diuretic NEC
  »carbonic acid anhydrase inhibitors
T50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Diuretic NEC
  »furfuryl NEC
T50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Diuretic NEC
  »loop (high-ceiling)
T50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Diuretic NEC
  »mercurial NEC
T50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Diuretic NEC
  »osmotic
T50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Diuretic NEC
  »purine NEC
T50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Diuretic NEC
  »saluretic NEC
T50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Diuretic NEC
  »sulfonamide
T50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Diuretic NEC
  »thiazide NEC
T50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Diuretic NEC
  »xanthine
T50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
DiurginT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
DiurilT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
EpitizideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
EthamideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
EthiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
EthoxzolamideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
FenquizoneT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
FlumethiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
HydrochlorothiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
HydroflumethiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
HydromoxT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
MefrusideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
MerallurideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
MerbaphenT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
MercaptomerinT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
MercumatilinT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
MercuramideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
MercurophyllineT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
MersalylT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
MethazolamideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
MethyclothiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
MeticraneT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
MetolazoneT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Osmotic diureticsT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
PenflutizideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
PolythiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Purine diureticsT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
QuinethazoneT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
RegrotonT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
ReneseT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Saluretic NECT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
SaluronT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
TeclothiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
TetrachlormethiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Thiazides (diuretics)T50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
ThiomercaptomerinT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
ThiomerinT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
TiamizideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
TriamtereneT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
TrichlormethiazideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
TripamideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
TrometamolT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
TromethamineT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
Xanthine diureticsT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
XipamideT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6
ZaroxolynT50.2X1T50.2X2T50.2X3T50.2X4T50.2X5T50.2X6

Patient Education


Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

  • Knowing your medicines. When you get a prescription, ask the name of the medicine and check to make sure that the pharmacy gave you the right medicine. Make sure that you understand how often you should take the medicine and how long you should take it.
  • Keeping a list of medicines.
    • Write down all of the medicines that you are taking, including the names of your medicines, how much you take, and when you take them. Make sure to include any over-the-counter medicines, vitamins, supplements, and herbs that you take.
    • List the medicines that you are allergic to or that have caused you problems in the past.
    • Take this list with you every time you see a health care provider.
  • Reading medicine labels and following the directions. Don't just rely on your memory - read the medication label every time. Be especially careful when giving medicines to children.
  • Asking questions. If you don't know the answers to these questions, ask your health care provider or pharmacist:
    • Why am I taking this medicine?
    • What are the common side effects?
    • What should I do if I have side effects?
    • When should I stop this medicine?
    • Can I take this medicine with the other medicines and supplements on my list?
    • Do I need to avoid certain foods or alcohol while taking this medicine?

Food and Drug Administration


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.