2024 ICD-10-CM Diagnosis Code T47.5X5D

Adverse effect of digestants, subsequent encounter

ICD-10-CM Code:
T47.5X5D
ICD-10 Code for:
Adverse effect of digestants, subsequent encounter
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system
        (T47)

T47.5X5D is a billable diagnosis code used to specify a medical diagnosis of adverse effect of digestants, subsequent encounter. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.

This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.

T47.5X5D is a subsequent encounter code, includes a 7th character and should be used after the patient has completed active treatment for a condition like adverse effect of digestants. According to ICD-10-CM Guidelines a "subsequent encounter" occurs when the patient is receiving routine care for the condition during the healing or recovery phase of treatment. Subsequent diagnosis codes are appropriate during the recovery phase, no matter how many times the patient has seen the provider for this condition. If the provider needs to adjust the patient's care plan due to a setback or other complication, the encounter becomes active again.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to bile acid and/or bile acid derivative
  • Adverse reaction to bile acid and/or bile acid derivative
  • Adverse reaction to chenodeoxycholic acid and/or ursodeoxycholic acid
  • Adverse reaction to chenodeoxycholic acid and/or ursodeoxycholic acid
  • Adverse reaction to digestant
  • Adverse reaction to lipotropic drugs
  • Adverse reaction to oil
  • Adverse reaction to pancreatin
  • Adverse reaction to papain
  • Adverse reaction to pepsin
  • Chenodeoxycholic acid adverse reaction
  • Dehydrocholic acid adverse reaction
  • Peppermint oil adverse reaction

Clinical Classification

Clinical Information

  • Betaine

    a naturally occurring compound that has been of interest for its role in osmoregulation. as a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (from martindale, the extra pharmacopoeia, 30th ed, p1341)
  • Betaine-Aldehyde Dehydrogenase

    an nad+ dependent enzyme that catalyzes the oxidation of betain aldehyde to betaine.
  • Betaine-Homocysteine S-Methyltransferase

    a zinc metalloenzyme that catalyzes the transfer of a methyl group from betaine to homocysteine to produce dimethylglycine and methionine, respectively. this enzyme is a member of a family of zinc-dependent methyltransferases that use thiols or selenols as methyl acceptors.
  • Chenodeoxycholic Acid

    a bile acid, usually conjugated with either glycine or taurine. it acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. it is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.
  • Cholic Acid

    a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. it facilitates fat absorption and cholesterol excretion.
  • Cholic Acids

    the 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholanic acid family of bile acids in man, usually conjugated with glycine or taurine. they act as detergents to solubilize fats for intestinal absorption, are reabsorbed by the small intestine, and are used as cholagogues and choleretics.
  • Citric Acid

    a key intermediate in metabolism. it is an acid compound found in citrus fruits. the salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
  • Citric Acid Cycle

    a series of oxidative reactions in the breakdown of acetyl units derived from glucose; fatty acids; or amino acids by means of tricarboxylic acid intermediates. the end products are carbon dioxide, water, and energy in the form of phosphate bonds.
  • Dehydrocholic Acid

    a semisynthetic bile acid made from cholic acid. it is used as a cholagogue, hydrocholeretic, diuretic, and as a diagnostic aid.
  • Asarum

    a plant genus of the family aristolochiaceae which was used medicinally by north american indians. the common name of 'snakeroot' is also used for many other plants, including sanicula; or aristolochia; or polygala.
  • Ginger

    deciduous plant rich in volatile oil (oils, volatile). it is used as a flavoring agent and has many other uses both internally and topically.
  • Glutamate Decarboxylase

    a pyridoxal-phosphate protein that catalyzes the alpha-decarboxylation of l-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. the enzyme is found in bacteria and in invertebrate and vertebrate nervous systems. it is the rate-limiting enzyme in determining gamma-aminobutyric acid levels in normal nervous tissues. the brain enzyme also acts on l-cysteate, l-cysteine sulfinate, and l-aspartate. ec 4.1.1.15.
  • Glutamates

    derivatives of glutamic acid. included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the 2-aminopentanedioic acid structure.
  • Glutamic Acid

    a non-essential amino acid naturally occurring in the l-form. glutamic acid is the most common excitatory neurotransmitter in the central nervous system.
  • Plasminogen

    precursor of plasmin (fibrinolysin). it is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. it is used in wound debriding and has been investigated as a thrombolytic agent.
  • RNA, Transfer, Glu

    a transfer rna which is specific for carrying glutamic acid to sites on the ribosomes in preparation for protein synthesis.
  • Pancreatin

    a mammalian pancreatic extract composed of enzymes with protease, amylase and lipase activities. it is used as a digestant in pancreatic malfunction.
  • Pancrelipase

    a preparation of hog pancreatic enzymes standardized for lipase content.
  • Coronavirus Papain-Like Proteases

    papain-like proteases that occur in species of coronaviridae. some species have more than one papain-like protease gene.
  • Papain

    a proteolytic enzyme obtained from carica papaya. it is also the name used for a purified mixture of papain and chymopapain that is used as a topical enzymatic debriding agent. ec 3.4.22.2.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system (T47). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

  • Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)

T47.5X5D is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.

CMS POA Indicator Options and Definitions

POA IndicatorReason for CodeCMS will pay the CC/MCC DRG?
YDiagnosis was present at time of inpatient admission.YES
NDiagnosis was not present at time of inpatient admission.NO
UDocumentation insufficient to determine if the condition was present at the time of inpatient admission.NO
WClinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.YES
1Unreported/Not used - Exempt from POA reporting. NO

Convert T47.5X5D to ICD-9-CM

  • ICD-9-CM Code: V58.89 - Other specfied aftercare
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Table of Drugs and Chemicals

The parent code T47.5X5 of the current diagnosis code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AmylaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Anise oilT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
AntiflatulentT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
b-galactosidaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
BetaineT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Bile saltsT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
CarminativeT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Chenodeoxycholic acidT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
ChenodiolT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
CholagoguesT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
CholereticT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Cholic acidT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Citric acidT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Cytochrome CT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
DecholinT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Dehydrocholic acidT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
DiastaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Digestant NECT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
DillT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
ElastaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
FlorantyroneT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
b-GalactosidaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Gastric enzymesT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
GentianT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Gentian
  »violet
T47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
GingerT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Ginger
  »Jamaica
T47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Glutamic acidT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
LipancreatinT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Ox bile extractT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
PancreatinT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
PancrelipaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
PapainT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Papain
  »digestant
T47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Peppermint (oil)T47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
PepsinT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Pepsin
  »digestant
T47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
PhenylpropanolT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
ProteaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
TilactaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.