2024 ICD-10-CM Diagnosis Code T45.2X1
Poisoning by vitamins, accidental (unintentional)
- ICD-10-CM Code:
- T45.2X1
- ICD-10 Code for:
- Poisoning by vitamins, accidental (unintentional)
- Is Billable?
- Not Valid for Submission
- Code Navigator:
T45.2X1 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of poisoning by vitamins, accidental (unintentional). The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.
Specific Coding Applicable to Poisoning by vitamins, accidental (unintentional)
Non-specific codes like T45.2X1 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for poisoning by vitamins, accidental (unintentional):
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Accidental vitamin A overdose
- Accidental vitamin A poisoning
- Accidental vitamin D and/or vitamin D derivative overdose
- Accidental vitamin D poisoning
- Ascorbic acid toxicity
- Cholecalciferol toxicity
- Poisoning by vitamin
- Poisoning by vitamin A
- Poisoning by vitamin D
- Pyridoxine toxicity
- Vitamin A overdose
- Vitamin B and/or vitamin B derivative overdose
- Vitamin B group poisoning
- Vitamin D and/or vitamin D derivative overdose
- Vitamin overdose
Clinical Information
Adenine
a purine base and a fundamental unit of adenine nucleotides.Adenine Nucleotide Translocator 1
a subtype of mitochondrial adp, atp translocase found primarily in heart muscle (myocardium) and skeletal muscle (muscle, skeletal).Adenine Nucleotide Translocator 2
a subtype of mitochondrial adp, atp translocase found primarily in fibroblasts.Adenine Nucleotide Translocator 3
a subtype of mitochondrial adp, atp translocase found primarily in the liver.Adenine Nucleotides
Adenine Phosphoribosyltransferase
an enzyme catalyzing the formation of amp from adenine and phosphoribosylpyrophosphate. it can act as a salvage enzyme for recycling of adenine into nucleic acids. ec 2.4.2.7.Deoxyadenosines
adenosine molecules which can be substituted in any position, but are lacking one hydroxyl group in the ribose part of the molecule.Mitochondrial ADP, ATP Translocases
a class of nucleotide translocases found abundantly in mitochondria that function as integral components of the inner mitochondrial membrane. they facilitate the exchange of adp and atp between the cytosol and the mitochondria, thereby linking the subcellular compartments of atp production to those of atp utilization.NAD
a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. it is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (nad+) and reduced (nadh). (dorland, 27th ed)Poly A
a group of adenine ribonucleotides in which the phosphate residues of each adenine ribonucleotide act as bridges in forming diester linkages between the ribose moieties.Vidarabine
a nucleoside antibiotic isolated from streptomyces antibioticus. it has some antineoplastic properties and has broad spectrum activity against dna viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the vaccinia virus and varicella zoster virus.Vidarabine Phosphate
an adenosine monophosphate analog in which ribose is replaced by an arabinose moiety. it is the monophosphate ester of vidarabine with antiviral and possibly antineoplastic properties.Ascorbic Acid
a six carbon compound related to glucose. it is found naturally in citrus fruits and many vegetables. ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. its biologically active form, vitamin c, functions as a reducing agent and coenzyme in several metabolic pathways. vitamin c is considered an antioxidant.Ascorbic Acid Deficiency
a condition due to a dietary deficiency of ascorbic acid (vitamin c), characterized by malaise, lethargy, and weakness. as the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. ascorbic acid deficiency frequently develops into scurvy in young children fed unsupplemented cow's milk exclusively during their first year. it develops also commonly in chronic alcoholism. (cecil textbook of medicine, 19th ed, p1177)Biotin
a water-soluble, enzyme co-factor present in minute amounts in every living cell. it occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.Biotinidase
an enzyme which catalyzes the release of biotin from biocytin. in human, defects in the enzyme are the cause of the organic acidemia multiple carboxylase deficiency or biotinidase deficiency.Biotinidase Deficiency
the late onset form of multiple carboxylase deficiency (deficiency of the activities of biotin-dependent enzymes propionyl-coa carboxylase, methylcrotonyl-coa carboxylase, and pyruvate carboxylase) due to a defect or deficiency in biotinidase which is essential for recycling biotin.Biotinylation
incorporation of biotinyl groups into molecules.Myoclonic Epilepsies, Progressive
a heterogeneous group of primarily familial epilepsy disorders characterized by myoclonic seizures, tonic-clonic seizures, ataxia, progressive intellectual deterioration, and neuronal degeneration. these include lafora disease; merrf syndrome; neuronal ceroid-lipofuscinosis; sialidosis (see mucolipidoses), and unverricht-lundborg syndrome.Calcifediol
the major circulating metabolite of vitamin d3. it is produced in the liver and is the best indicator of the body's vitamin d stores. it is effective in the treatment of rickets and osteomalacia, both in azotemic and non-azotemic patients. calcifediol also has mineralizing properties.Calcitriol
the physiologically active form of vitamin d. it is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (calcifediol). its production is stimulated by low blood calcium levels and parathyroid hormone. calcitriol increases intestinal absorption of calcium and phosphorus, and in concert with parathyroid hormone increases bone resorption.Receptors, Calcitriol
proteins, usually found in the cytoplasm, that specifically bind calcitriol, migrate to the nucleus, and regulate transcription of specific segments of dna with the participation of d receptor interacting proteins (called drip). vitamin d is converted in the liver and kidney to calcitriol and ultimately acts through these receptors.Vitamin D3 24-Hydroxylase
a cytochrome p-450 enzyme that has specificity for cholecalciferol (vitamin d3). it hydroxylates the molecule at carbon position 24.Cholecalciferol
derivative of 7-dehydroxycholesterol formed by ultraviolet rays breaking of the c9-c10 bond. it differs from ergocalciferol in having a single bond between c22 and c23 and lacking a methyl group at c24.Dihydrotachysterol
a vitamin d that can be regarded as a reduction product of vitamin d2.Esculin
a derivative of coumarin with molecular formula c15h16o9.Niacinamide
an important compound functioning as a component of the coenzyme nad. its primary significance is in the prevention and/or cure of blacktongue and pellagra. most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.Pantothenic Acid
a butyryl-beta-alanine that can also be viewed as pantoic acid complexed with beta alanine. it is incorporated into coenzyme a and protects cells against peroxidative damage by increasing the level of glutathione.Pyridoxal Phosphate
this is the active form of vitamin b 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. during transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).Pyridoxal Kinase
an enzyme that catalyzes reversibly the phosphorylation of pyridoxal in the presence of atp with the formation of pyridoxal 5-phosphate and adp. pyridoxine, pyridoxamine and various derivatives can also act as acceptors. ec 2.7.1.35.Pyridoxaminephosphate Oxidase
an enzyme catalyzing the deamination of pyridoxaminephosphate to pyridoxal phosphate. it is a flavoprotein that also oxidizes pyridoxine-5-phosphate and pyridoxine. ec 1.4.3.5.Pyridoxic Acid
the catabolic product of most of vitamin b 6; (pyridoxine; pyridoxal; and pyridoxamine) which is excreted in the urine.Pyridoxine
the 4-methanol form of vitamin b 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. although pyridoxine and vitamin b 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (ee snell; ann ny acad sci, vol 585 pg 1, 1990).Pyrithioxin
a neurotropic agent which reduces permeability of blood-brain barrier to phosphate. it has no vitamin b6 activity.Vitamin B 6 Deficiency
a nutritional condition produced by a deficiency of vitamin b 6 in the diet, characterized by dermatitis, glossitis, cheilosis, and stomatitis. marked deficiency causes irritability, weakness, depression, dizziness, peripheral neuropathy, and seizures. in infants and children typical manifestations are diarrhea, anemia, and seizures. deficiency can be caused by certain medications, such as isoniazid.Flavin Mononucleotide
a coenzyme for a number of oxidative enzymes including nadh dehydrogenase. it is the principal form in which riboflavin is found in cells and tissues.Riboflavin
nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. the richest natural source is yeast. it occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide.Riboflavin Deficiency
a dietary deficiency of riboflavin causing a syndrome chiefly marked by cheilitis, angular stomatitis, glossitis associated with a purplish red or magenta-colored tongue that may show fissures, corneal vascularization, dyssebacia, and anemia. (dorland, 27th ed)Riboflavin Synthase
an enzyme that catalyzes the formation of riboflavin from two molecules of 6,7-dimethyl-8-ribityllumazine, utilizing a four-carbon fragment from one molecule which is transferred to the second molecule. ec 2.5.1.9.Fursultiamin
compound used for therapy of thiamine deficiency. it has also been suggested for several non-deficiency disorders but has not yet proven useful.Maple Syrup Urine Disease
an autosomal recessive inherited disorder with multiple forms of phenotypic expression, caused by a defect in the oxidative decarboxylation of branched-chain amino acids (amino acids, branched-chain). these metabolites accumulate in body fluids and render a "maple syrup" odor. the disease is divided into classic, intermediate, intermittent, and thiamine responsive subtypes. the classic form presents in the first week of life with ketoacidosis, hypoglycemia, emesis, neonatal seizures, and hypertonia. the intermediate and intermittent forms present in childhood or later with acute episodes of ataxia and vomiting. (from adams et al., principles of neurology, 6th ed, p936)Thiamin Pyrophosphokinase
an enzyme that catalyzes the formation of thiamine pyrophosphate from atp and thiamine. ec 2.7.6.2.Thiamine
3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride.Thiamine Deficiency
a nutritional condition produced by a deficiency of thiamine in the diet, characterized by anorexia, irritability, and weight loss. later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. in addition to being caused by a poor diet, thiamine deficiency in the united states most commonly occurs as a result of alcoholism, since ethanol interferes with thiamine absorption. in countries relying on polished rice as a dietary staple, beriberi prevalence is very high. (from cecil textbook of medicine, 19th ed, p1171)Thiamine Monophosphate
thiamine dihydrogen phosphate ester. the monophosphate ester of thiamine. synonyms: monophosphothiamine; vitamin b1 monophosphate.Thiamine Pyrophosphatase
an enzyme that hydrolyzes thiamine pyrophosphate to thiamine monophosphate plus inorganic phosphate. ec 3.6.1.-.Thiamine Pyrophosphate
the coenzyme form of vitamin b1 present in many animal tissues. it is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.Thiamine Triphosphate
3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)thiazolium hydroxide, inner salt, p,p',p''-trioxide. the triphosphate ester of thiamine. in leigh's disease, this compound is present in decreased amounts in the brain due to a metabolic block in its formation.Thiamin-Triphosphatase
an enzyme present in nerve tissue. it catalyzes reversibly the formation of thiamine diphosphate and orthophosphate from thiamine triphosphate. ec 3.6.1.28.
Coding Guidelines
When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified (T45). Use the following options for the aplicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Tabular List of Diseases and Injuries
The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.
Inclusion Terms
Inclusion TermsThese terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- Poisoning by vitamins NOS
Table of Drugs and Chemicals
The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.
According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.
Patient Education
Medication Errors
Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:
- Knowing your medicines. When you get a prescription, ask the name of the medicine and check to make sure that the pharmacy gave you the right medicine. Make sure that you understand how often you should take the medicine and how long you should take it.
- Keeping a list of medicines.
- Write down all of the medicines that you are taking, including the names of your medicines, how much you take, and when you take them. Make sure to include any over-the-counter medicines, vitamins, supplements, and herbs that you take.
- List the medicines that you are allergic to or that have caused you problems in the past.
- Take this list with you every time you see a health care provider.
- Reading medicine labels and following the directions. Don't just rely on your memory - read the medication label every time. Be especially careful when giving medicines to children.
- Asking questions. If you don't know the answers to these questions, ask your health care provider or pharmacist:
- Why am I taking this medicine?
- What are the common side effects?
- What should I do if I have side effects?
- When should I stop this medicine?
- Can I take this medicine with the other medicines and supplements on my list?
- Do I need to avoid certain foods or alcohol while taking this medicine?
Food and Drug Administration
[Learn More in MedlinePlus]
Vitamins
Vitamins are substances that your body needs to grow and develop normally. There are 13 vitamins your body needs. They are:
- Vitamin A
- B vitamins (thiamine, riboflavin, niacin, pantothenic acid, biotin, vitamin B-6, vitamin B-12 and folate)
- Vitamin C
- Vitamin D
- Vitamin E
- Vitamin K
You can usually get all your vitamins from the foods you eat. Your body can also make vitamins D and K. People who eat a vegetarian diet may need to take a vitamin B12 supplement.
Each vitamin has specific jobs. If you have low levels of certain vitamins, you may get health problems. For example, if you don't get enough vitamin C, you could become anemic. Some vitamins may help prevent medical problems. Vitamin A prevents night blindness.
The best way to get enough vitamins is to eat a balanced diet with a variety of foods. In some cases, you may need to take vitamin supplements. It's a good idea to ask your health care provider first. High doses of some vitamins can cause problems.
[Learn More in MedlinePlus]
Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.