2024 ICD-10-CM Diagnosis Code T44.991A

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• Overdose of dopamine receptor agonist

Clinical Information

• Arylsulfotransferase

  a sulfotransferase that catalyzes the sulfation of a phenol in the presence of 3'-phosphoadenylylsulfate as sulfate donor to yield an aryl sulfate and adenosine 3',5'-bisphosphate. a number of aromatic compounds can act as acceptors; however, organic hydroxylamines are not substrates. sulfate conjugation by this enzyme is a major pathway for the biotransformation of phenolic and catechol drugs as well as neurotransmitters. ec 2.8.2.1.

• Dopamine

  one of the catecholamine neurotransmitters in the brain. it is derived from tyrosine and is the precursor to norepinephrine and epinephrine. dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. a family of receptors (receptors, dopamine) mediate its action.

• Dopamine Agents

  any drugs that are used for their effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.

• Dopamine Agonists

  drugs that bind to and activate dopamine receptors.

• Dopamine and cAMP-Regulated Phosphoprotein 32

  a phosphoprotein that was initially identified as a major target of dopamine activated adenylyl cyclase in the corpus striatum. it regulates the activities of protein phosphatase-1 and protein kinase a, and it is a key mediator of the biochemical, electrophysiological, transcriptional, and behavioral effects of dopamine.

• Dopamine Antagonists

  drugs that bind to but do not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists. many drugs used in the treatment of psychotic disorders (antipsychotic agents) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. dopamine antagonists have been used for several other clinical purposes including as antiemetics, in the treatment of tourette syndrome, and for hiccup. dopamine receptor blockade is associated with neuroleptic malignant syndrome.

• Dopamine beta-Hydroxylase

• Dopamine D2 Receptor Antagonists

  compounds and drugs that bind to and inhibit or block the activation of dopamine d2 receptors.

• Dopamine Plasma Membrane Transport Proteins

  sodium chloride-dependent neurotransmitter symporters located primarily on the plasma membrane of dopaminergic neurons. they remove dopamine from the extracellular space by high affinity reuptake into presynaptic terminals and are the target of dopamine uptake inhibitors.

• Dopamine Uptake Inhibitors

  drugs that block the transport of dopamine into axon terminals or into storage vesicles within terminals. most of the adrenergic uptake inhibitors also inhibit dopamine uptake.

• Dopaminergic Imaging

  functional brain imaging techniques that utilize various radionuclide tracers that bind to different targets in the synapses of dopaminergic neurons.

• Dopaminergic Neurons

  neurons whose primary neurotransmitter is dopamine.

• Receptors, Dopamine

  cell-surface proteins that bind dopamine with high affinity and trigger intracellular changes influencing the behavior of cells.

• Receptors, Dopamine D1

  a subfamily of g-protein-coupled receptors that bind the neurotransmitter dopamine and modulate its effects. d1-class receptor genes lack introns, and the receptors stimulate adenylyl cyclases.

• Receptors, Dopamine D2

  a subfamily of g-protein-coupled receptors that bind the neurotransmitter dopamine and modulate its effects. d2-class receptor genes contain introns, and the receptors inhibit adenylyl cyclases.

• Receptors, Dopamine D3

  a subtype of dopamine d2 receptors that are highly expressed in the limbic system of the brain.

• Receptors, Dopamine D4

  a subtype of dopamine d2 receptors that has high affinity for the antipsychotic clozapine.

• Receptors, Dopamine D5

  a subtype of dopamine d1 receptors that has higher affinity for dopamine and differentially couples to gtp-binding proteins.

• Ephedra

  a plant genus of the family ephedraceae, order ephedrales, class gnetopsida, division gnetophyta.

• Ephedra sinica

  a plant species of the family ephedraceae, order ephedrales, class gnetopsida, division gnetophyta. it is a source of ephedrine and other alkaloids.

• Ephedrine

  a phenethylamine found in ephedra sinica. pseudoephedrine is an isomer. it is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. it has been used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. it has become less extensively used with the advent of more selective agonists.

• Pseudoephedrine

  a phenethylamine that is an isomer of ephedrine which has less central nervous system effects and usage is mainly for respiratory tract decongestion.

• Mephentermine

  a sympathomimetic agent with specificity for alpha-1 adrenergic receptors. it is used to maintain blood pressure in hypotensive states such as following spinal anesthesia.

• Phenylpropanolamine

  a sympathomimetic that acts mainly by causing release of norepinephrine but also has direct agonist activity at some adrenergic receptors. it is most commonly used as a nasal vasoconstrictor and an appetite depressant.

Coding Guidelines

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system (T44). Use the following options for the aplicable episode of care:

• A - initial encounter
• D - subsequent encounter
• S - sequela

T44.991A is grouped with Diagnostic Related Groups - MS-DRG Mapping

Diagnostic Related Groups (DRGs) are a classification system used to group together diagnosis codes for the purpose of reimbursement and healthcare management. DRGs are used to standardize the way hospitals and other providers are paid for inpatient services. In this system patients are grouped together based on their principal diagnosis in areas referred to as Major Diagnostic Categories (MDC). Once a patient is assigned a particular diagnostic category, providers receive a predetermined payment rate for the services rendered. This reimbursement rate is often fixed and is meant to cover the cost of care for that patient. Reimbursement is also affected by the relative weight of a diagnostic related group based on the severity of a patient's illness and the associated cost of care during hospitalization.

Diagnostic related groups encourage healthcare providers to focus on quality and efficiency in patient care while managing costs effectively. The diagnosis code is present in the following groups for version MS-DRG V41.0 applicable from 10/01/2023 through 09/30/2024.

The relative weight of a diagnostic related group determines the reimbursement rate based on the severity of a patient's illness and the associated cost of care during hospitalization.

Convert T44.991A to ICD-9-CM

• ICD-9-CM Code: 971.9 - Pois-autonomic agent NOS
  Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment.
• ICD-9-CM Code: E855.8 - Acc poison-cns drug NEC
  Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment.

Table of Drugs and Chemicals

The parent code T44.991 of the current diagnosis code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Patient Education

Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

• Knowing your medicines. When you get a prescription, ask the name of the medicine and check to make sure that the pharmacy gave you the right medicine. Make sure that you understand how often you should take the medicine and how long you should take it.
• Keeping a list of medicines.
• Write down all of the medicines that you are taking, including the names of your medicines, how much you take, and when you take them. Make sure to include any over-the-counter medicines, vitamins, supplements, and herbs that you take.
• List the medicines that you are allergic to or that have caused you problems in the past.
• Take this list with you every time you see a health care provider.
• Reading medicine labels and following the directions. Don't just rely on your memory - read the medication label every time. Be especially careful when giving medicines to children.
• Asking questions. If you don't know the answers to these questions, ask your health care provider or pharmacist:
• Why am I taking this medicine?
• What are the common side effects?
• What should I do if I have side effects?
• When should I stop this medicine?
• Can I take this medicine with the other medicines and supplements on my list?
• Do I need to avoid certain foods or alcohol while taking this medicine?

Food and Drug Administration

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.